Subjective evaluation of the frequency of coffee intake and relationship to osteoporosis in Chinese men

Abstract

Background: The main purpose of this study was to evaluate the associations between frequency of coffee intake and osteoporosis (OP) in a general Chinese male sample.

Methods: We conducted a large-scale, community-based, cross-sectional study to investigate the associations by using a self-report questionnaire to estimate the frequency of coffee intake. A total of 992 men were available for data analysis in this study. Multiple regression models controlling for confounding factors to include frequency of coffee intake variable were performed to investigate the relationships for OP.

Results: Positive correlations between frequency of coffee intake and T-score were reported (β = 0.211, P = 0.024). Multiple regression analysis indicated that the frequency of coffee intake was significantly associated with OP (P < 0.05 for model 1 and model 2). The men with moderate frequency of coffee intake had a lower prevalence of OP.

Conclusions: The findings indicated that consumption of coffee was independently and significantly associated with OP. The prevalence of OP was less frequent in Chinese men with moderate coffee intake.

Trial registration: ClinicalTrials.gov, NCT02451397.

Keywords: Association; Chinese men; Coffee intake; Frequency; Osteoporosis.

Figures

Fig. 1

Comparison of T-score among groups according to frequency of coffee intake. a The results of comparison of T-score among groups according to model 1 (frequency of coffee intake were categorized by group 1: seldom, group 2: once or twice per week and group 3: greater than or equal to once per 2 days). The mean T-score was −1.26, −1.05, and −1.05 in the three groups, respectively. There were no significantly differences among the three groups (P = 0.079). b The results of comparison of T-score among groups according to model 2 (frequency of coffee intake were categorized by group 1: seldom, group 2: moderate). The mean T-score was −1.26 and −1.05 in the two groups, respectively. There were significantly differences between the two groups (P = 0.024)

Fig. 2

Comparison of prevalence of osteoporosis among groups according to frequency of coffee intake. a The results of comparison of prevalence of osteoporosis among groups according to model 1 (frequency of coffee intake were categorized by group 1: seldom, group 2: once or twice per week and group 3: greater than or equal to once per 2 days). The prevalence of osteoporosis was 9.82, 3.57, and 2.0 % in the three groups, respectively. There were significant differences among the three groups (P = 0.023 and P value for trend = 0.020). b The results of comparison of prevalence of osteoporosis among groups according to model 2 (frequency of coffee intake were categorized by group 1: seldom, group 2: moderate). The prevalence of osteoporosis was 9.82 and 2.84 % in the two groups, respectively. There were significant differences between the two groups (P = 0.029 and P value for trend = 0.007)