NeuroInterp: a method for facilitating neuroimaging research on cerebral malaria

Abstract

Radiologic data are increasingly important in clinical care guidelines for neurologic disorders and in the conduct of clinical trials assessing novel therapies. The infrastructure and expertise for neuroradiologic evaluations remain scarce in resource-limited settings, but where available, MRI and CT capacity can offer new insights into common, globally devastating diseases. In vivo data for frequently fatal tropical conditions such as cerebral malaria have been largely limited to autopsy studies, which only provide information on nonsurvivors at a single point in time. New imaging facilities in sub-Saharan African offer opportunities for expanded research on tropical neurologic disorders.1 However, data management challenges hamper the research utility of radiologic evaluations.

Figures

Figure 1. Workflow for NeuroInterp

MSU = Michigan State University; PACS = picture archiving and communication system.

Figure 2. NeuroInterp work screen for reading and adjudication