Frequency of Vitamin D deficiency in pregnant diabetics at Baskent University Hospital, Istanbul

Hulya Parildar, Asli Dogruk Unal, Guldeniz Aksan Desteli, Ozlem Cigerli, Nilgun Guvener Demirag, Hulya Parildar, Asli Dogruk Unal, Guldeniz Aksan Desteli, Ozlem Cigerli, Nilgun Guvener Demirag

Abstract

Objective: To find out the frequency of vitamin D deficiency and its relation with glucose parameters and the incidence of gestational diabetes (GDM).

Methodology: Gestational diabetes was diagnosed with 75 gram oral glucose tolerance test. Forty-four pregnant women diagnosed with GDM and 78 non-GDM pregnant women were enrolled as case and control group, respectively in this descriptive study. Vitamin D status was classified as deficiency at ≤20 ng/ml for serum 25(OH)D concentrations.

Results: The mean ages were 33.4±5.2 (18-44) years and 29.7±4.1 (21-39) years, mean BMI was 30.6±5.9 kg/m² (19.5-46.1) and 25.9±4.4 kg/m2 (16.5-38) in case and control groups, respectively. The frequency of GDM was found 9.38%. The mean serum vitamin D levels in GDM group were significantly lower than in non-GDM subjects (p=0.07). A total of 56.8% of GDM patients were compared with 35.8% of control group which had Vitamin D deficiency and the difference was significant (p= 0.02). There was no significant association between vitamin D levels and fasting glucose, insulin and HbA1c. Vitamin D levels were inversely correlated with clothing style, parathyroid hormone levels, dental problems and muscle cramps.

Conclusions: The association of maternal Vitamin D status with the markers of glucose metabolism in pregnancy needs prospective studies.

Keywords: Gestational diabetes; Nutrition in pregnancy; Vitamin D.

Figures

Fig.1
Fig.1
The correlation between serum Vitamin D and PTH levels
Fig.2
Fig.2
Serum Vitamin D levels in veiled and nonveiled pregnant
Fig.3
Fig.3
Vitamin D levels and the frequency of muscle cramps (x²=3.57, p=0.05).
Fig.4
Fig.4
Vitamin D levels and the frequency of dental problems (x²=4.67, p=0.03).

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Source: PubMed

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