Pragmatic randomised controlled trial of preferred intensity exercise in women living with depression

Patrick Callaghan, Elizabeth Khalil, Ioannis Morres, Tim Carter, Patrick Callaghan, Elizabeth Khalil, Ioannis Morres, Tim Carter

Abstract

Background: Exercise may be effective in treating depression, but trials testing its effect in depressed women are rare.

Aim: To compare the effect of exercise of preferred intensity with exercise of prescribed intensity in thirty-eight women living with depression.

Methods: A Pragmatic RCT of 12 sessions of exercise at preferred intensity compared with 12 sessions at prescribed intensity. Beck Depression Inventory (BDI), Rosenberg Self Esteem Scale (RSES), General Health Questionnaire 12 (GHQ-12), heart rate (HR), Rating of Perceived Exertion Scale (RPE), Quality of Life in Depression Scale (QLDS), Multi-Dimensional Scale of Perceived Social Support (MDSPSS), SF12 Health Survey and exercise participation rates were compared between groups.

Results: Intervention participants had statistically better BDI (t = 2.638, df = 36, p = 0.006, 95% mean (SD) 26.5 (10.7), CI-20.4 to -2.7, d = 0.86), GHQ-12 (t = 3.284, df = 36, p = 0.001, mean (SD) 8.3 (3.7) 95% CI -6.5 to -1.5, d = 1.08), RSES (t = 2.045, df = 36, p = 0.024, mean (SD) 11.3 (5.8), 95% CI 0.3 -6.4, d = 0.25), QLDS (t = 1.902, df = 36, p = 0.0325, mean (SD) 15.5 (7.9), 95% CI -12.2 -0.4, d = 0.27) RPE scores (t = 1.755, df = 36, p = 0.0475, mean (SD) 9.2 (3.2), 95% CI -.5 - 5.2, d = 0.77) and attended more exercise sessions (t = 1.781, df = 36, p = 0.0415, number of sessions 8 (65%), 95% CI-0.3 -4.8, d = 0.58). SF-12, MSPSS and HR did not differ significantly between groups.

Conclusions: Exercise of preferred intensity improves psychological, physiological and social outcomes, and exercise participation rates in women living with depression.

Trial registration: ClinicalTrials.gov: NCT00546221.

Figures

Figure 1
Figure 1
Flow of participants through the study.

References

    1. Robson D, Gray R. Serious Mental Illness and Physical Health Problems: A discussion paper. International Journal of Nursing Studies. 2007;44:457–466. doi: 10.1016/j.ijnurstu.2006.07.013.
    1. Richardson CR, Faulkner G, McDevitt J, Skrinar GS, Htuchinson DS, Piette JD. Integrating Physical Activity Into Mental Health Services for Persons With Serious Mental Illness. Psychiatric Services. 2005;56:324–331. doi: 10.1176/appi.ps.56.3.324.
    1. Craft LL, Landers DM. The effect of exercise on clinical depression and depression resulting from mental illness: a meta analysis. Journal of Sport and Exercise Psychology. 1998;20:339–357.
    1. Barbui C, Butler R, Cipriani A, Geddes J, Hatcher S. Depression in adults (drugs and other physical treatments. BMJ Clinical Evidence. 2007;06(1003):1–27.
    1. Callaghan P. Exercise: a neglected intervention in mental health care? Journal of Psychiatric and Mental Health Nursing. 2004;11:476–483. doi: 10.1111/j.1365-2850.2004.00751.x.
    1. Mead GE, Morley W, Campbell P, Greig CA, McMurdo M, Lawlor DA. Exercise for Depression (Review) Cochrane Database of Systematic Reviews. 2009. Art. No. CD004366.
    1. National Institute of Health and Clinical Excellence. Clinical Guideline 28. London, NICE; 2005. Depression in Children and Young People.
    1. Richardson CR, Faulkner G, McDevitt J, Skrinar GS, Htuchinson DS, Piette JD. Integrating Physical Activity Into Mental Health Services for Persons With Serious Mental Illness. Psychiatric Services. 2005;56:324–331. doi: 10.1176/appi.ps.56.3.324.
    1. McGeorge S. Couch Kids: The continuing epidemic. London, British Heart Foundation; 2004.
    1. Department of Health. Health Survey for England 2002: The Health of Children and Young People. London, Department of Health; 2002.
    1. Morgan WP. Prescription of Physical activity: a paradigm shift. Quest. 2001;53:366–382.
    1. Callaghan P, Norman P. A prospective evaluation of the Theory of Planned Behaviour (TPB) and the Transtheoretcial Model of Change (TTM) on exercise in young people. Psychology and Health. 2004;19(Suppl):29–30.
    1. Callaghan P, Eves FF, Norman P, Cheung YL, Chang AM. Applying the transtheoretical model of change to exercise in young Chinese people. British Journal of Health Psychology. 2002;7:267–282. doi: 10.1348/135910702760213670.
    1. Callaghan P, Norman P. Motivations and predictors of exercise in Chinese high school children. International Journal of Behavioral Medicine. 2000;7(suppl 1):23–24.
    1. Borg G. Borg's perceived exertion and pain scales. Stockholm: Human Kinetics; 1998.
    1. Callaghan P, Khalil E, Morres I. A prospective evaluation of the Transtheoretical Model of Change applied to exercise in young people. International Journal of Nursing Studies. 2010;47:3–12. doi: 10.1016/j.ijnurstu.2009.06.013.
    1. Oakley A, Strange V, Bonell C, Allen E, Stephenson J. Process evaluation in randomised controlled trials of complex interventions. British Medical Journal. 2006;332:413–16. doi: 10.1136/bmj.332.7538.413.
    1. Beck AT, Brown G K. Beck Depression Inventory®--II (BDI®-II), Harcourt Assessment, Inc. 1996.
    1. Goldberg DP, Williams P. A User's Guide to the General Health Questionnaire. Windsor: NFER-Nelson; 1988.
    1. Ware JE, Sherbourne CD. The MOS 36 item Short-Form Health Survey (SF-36). Conceptual Framework and item selection. Medical Care. pp. 473–83.
    1. Rosenberg M. Society and the Adolescent Self-Image. Princeton, NJ: Princeton University Press; 1965.
    1. Tuynman-Qua H, de Jonghe F, McKenna S. Quality of Life in Depression Scale (QLDS). Development, reliability, responsiveness and application. European Psychiatry. 1997;12(4):199–202. doi: 10.1016/S0924-9338(97)89105-5.
    1. Dahlem NW, Zimet GD, Wlaker IR. The Multidimensional Scale of perceived social support: A confirmation study. Journal of Clinical Psychology. 1991;47:756–761. doi: 10.1002/1097-4679(199111)47:6<756::AID-JCLP2270470605>;2-L.
    1. Callaghan P, Khalil E, Morres I. Report to the Burdett Trust for Nursing. Pragmatic Randomised Controlled Trial of a preferred intensity exercise programme to improve well being outcomes of women living with depression. 2010.
    1. Owen S, Khalil E. Meeting the physical health needs of adults with serious and enduring mental illness in community settings. The University of Nottingham; 2006.
    1. Sorensen JB, Skovgrad T, Puggrad L. Exercise on prescription in general practice: a systematic review. Scandiavian Journal of Primary Health Care. 2006;24:69–74. doi: 10.1080/02813430600700027.
    1. Crone D, Johnston lH, Gidlow C, Henley C, James DVB. Uptake and Participation in Physical Activity Referral Schemes in the UK: An Investigation of Patients Referred with Mental Health Problems. Issues in Mental Health Nursing. 2008;29(10):1088–1097. doi: 10.1080/01612840802319837.

Source: PubMed

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