Evaluation of the meibomian glands using the tear interferometer wearing orthokeratology lenses

Jiyoung Lee, Gyudeok Hwang, Minji Ha, Hyun-Seung Kim, Kyungdo Han, Kyung-Sun Na, Jiyoung Lee, Gyudeok Hwang, Minji Ha, Hyun-Seung Kim, Kyungdo Han, Kyung-Sun Na

Abstract

Background: To investigate the impact of orthokeratology wear on meibomian glands in Korean pediatric population using the tear interferometer.

Methods: Fifty-three orthokeratology wearers and 79 non-lens wearers were evaluated using the LipiView® II ocular surface interferometer which shows incomplete blink rate, average lipid layer thickness, and meiboscores.

Results: No significant differences in the incomplete blink rate and meiboscores for upper eyelids, but the lipid layer thickness and meiboscores for lower eyelids were significantly higher in the Ortho-K group than in the control group (p = 0.024 and 0.007, respectively). Correlation analysis showed no significant correlation between the duration of orthokeratology wear and the parameters measured by LipiView® (p > 0.05 for all). Among subgroups based on average duration of lens wear, the longer duration (≥ 24 months) subgroup showed higher meiboscores of lower eyelids (p = 0.011), but no other significant differences.

Conclusions: Ortho-K wearers showed no significant differences in the incomplete blink rate and meiboscores of upper eyelids, but they were associated with increased LLT and higher meiboscores of lower eyelids. Thorough examination and close monitoring of orthokeratology wearers is necessary. Prospective and observational studies are needed to further elucidate the relationship between Orthokeratology and meibomian glands.

Keywords: Blinking; Dry eye; Lipid layer thickness; Meibomian gland; Orthokeratology; Pediatric; Tear film.

Conflict of interest statement

There are no conflicts of interest to declare.

© 2022. The Author(s).

Figures

Fig. 1
Fig. 1
Representative cases involving children examined by the LipiView® II Ocular Surface Interferometer without (candidate group) and with orthokeratology lens wear (Ortho-K group). a Images for a 14-year old girl from the control group. The average lipid layer thicknesses in the right and left eyes of the girl were 92 and 97 nm, respectively. In addition, she did not show any signs of MGs loss in the upper and lower eyelids. b Images for a 10-year old boy from the Ortho-K group. He showed average lipid layer thicknesses of 59 and 55 nm in the right and left eyes, respectively, with corresponding incomplete blinking rates of 100% and 25%. A 25% MGs loss was noted in the distal portion of the upper and lower eyelids (white outlined contour)

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Source: PubMed

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