Ultrasonographic measurement of the median nerve in patients with rheumatoid arthritis without symptoms or signs of carpal tunnel syndrome

Hilde Berner Hammer, Espen A Haavardsholm, Tore Kristian Kvien, Hilde Berner Hammer, Espen A Haavardsholm, Tore Kristian Kvien

Abstract

Objectives: Ultrasonography (US) has shown increased cross-sectional area of the median nerve in carpal tunnel syndrome (CTS). Knowledge of the normal distribution of the areas is a prerequisite to evaluate pathology. Presently, the distribution of cross-sectional areas of the median nerve was explored in patients with rheumatoid arthritis (RA).

Methods: The median nerves of patients with RA having no symptoms or signs of CTS were examined with bilateral US at the entrance of the carpal tunnel.

Results: A total of 154 patients with RA were included. The median nerve was divided in 11.7% of the hands. The mean (SD) cross-sectional areas of the undivided median nerves were not significantly different on either sides (8.3 (1.5) mm(2) on the right side and 8.3 (1.4) mm(2) on the left side). The areas of the examined 308 median nerves ranged from 5.0 to 12.8 mm(2), with the 97.5 centile being 11.1 mm(2). Areas >10.0 mm(2) were found in 10% of the patients.

Conclusions: The mean cross-sectional areas of the median nerve in patients with RA were similar to those reported in healthy controls. However, 10% of the patients had values that overlap with areas commonly reported in patients with mild idiopathic CTS.

Conflict of interest statement

Competing interests: None declared.

Figures

https://www.ncbi.nlm.nih.gov/pmc/articles/instance/1954652/bin/ar55988.f1.jpg
https://www.ncbi.nlm.nih.gov/pmc/articles/instance/1954652/bin/ar55988.f2.jpg

References

    1. Ziswiler H ‐ R, Reichenbach S, Vögelin E, Bachmann L M, Villiger P M, Jüni P. Diagnostic value of sonography in patients with suspected carpal tunnel syndrome: a prospective study. Arthritis Rheum 200552304–311.
    1. Wong S M, Griffith J F, Hui A C, Lo S K, Fu M, Wong K S. Carpal tunnel syndrome: diagnostic usefulness of sonography. Radiology 200423293–99.
    1. Yesildag A, Kutluhan S, Sengul N, Koyuncuoglu H R, Oyar O, Guler al The role of ultrasonographic measurements of the median nerve in the diagnosis of carpal tunnel syndrome. Clin Radiol 200459910–915.
    1. Nakamichi K ‐ I, Tachibana S. Ultrasonographic measurement of median nerve cross sectional area in idiopathic carpal tunnel syndrome: diagnostic accuracy. Muscle Nerve 200226798–803.
    1. Wong S M, Griffith J F, Hui A C F, Tang A, Wong K S. Discriminatory sonographic criteria for the diagnosis of carpal tunnel syndrome. Arthritis Rheum 2002461914–1921.
    1. Swen W A A, Jacobs J W G, Bussemaker F E A M, de Waard J ‐ W D, Bijlsma J W J. Carpal tunnel sonography by the rheumatologist versus nerve conduction study by the neurologist. J Rheumatol 20012862–69.
    1. Nakamichi K ‐ I, Tachibana S. Enlarged median nerve in idiopathic carpal tunnel syndrome. Muscle Nerve 2000231713–1718.
    1. Lee D, van Holsbeeck M T, Janevski P K, Ganos D L, Ditmars D M, Darian V B. Diagnosis of carpal tunnel syndrome. Ultrasound versus electromyography. Radiol Clin North Am 199937859–872.
    1. Buchberger W, Schön G, Strasser K, Jungwirth W. High‐resolution ultrasonography of the carpal tunnel. J Ultrasound Med 199110531–537.
    1. Duncan I, Sullivan P, Lomas F. Sonography in the diagnosis of carpal tunnel syndrome. Am J Roentgenol 1999173681–684.
    1. El Miedany Y M, Aty S A, Ashour S. Ultrasonography versus nerve conduction study in patients with carpal tunnel syndrome: substantive or complementary test? Rheumatology 200443887–895.
    1. Hammer H B, Hovden I A H, Haavardsholm E A, Kvien T K. Ultrasonography shows increased cross‐sectional area of the median nerve in patients with arthritis and carpal tunnel syndrome. Rheumatology 200645584–588.
    1. Arnett F C, Edworthy S M, Bloch D A, McShane D J, Fries J F, Cooper N al The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 198831315–324.
    1. Werner R A, Jacobson J A, Jamadar D A. Influence of body mass index on median nerve function, carpal canal pressure, and cross‐sectional area of the median nerve. Muscle Nerve 200430481–485.

Source: PubMed

3
Abonnieren