Utilizing Soccer for Delivery of HIV and Substance Use Prevention for Young South African Men: 6-Month Outcomes of a Cluster Randomized Controlled Trial

Stephan Rabie, Mark Tomlinson, Ellen Almirol, Jackie Stewart, Zwelibanzi Skiti, Robert E Weiss, Lodewyk Vogel, Mary Jane Rotheram-Borus, Stephan Rabie, Mark Tomlinson, Ellen Almirol, Jackie Stewart, Zwelibanzi Skiti, Robert E Weiss, Lodewyk Vogel, Mary Jane Rotheram-Borus

Abstract

Young men in South Africa face the intersecting epidemics of HIV, substance use and endemic poverty. We tested the effectiveness of a behavioral intervention using soccer training to reduce the cluster of risks associated with HIV and substance use. This cluster randomized controlled trial was conducted with men aged 18-29 years old in 27 neighborhoods in the townships of Cape Town, South Africa. Neighborhoods were randomized to receive for 6 months either: (1) Soccer League (SL; n = 18 neighborhoods, n = 778 men) who attended soccer three times weekly (72 sessions; 94% uptake, 45.5% weekly attendance rate), combined with an HIV/substance use, cognitive-behavioral intervention; or (2) a Control Condition (CC; n = 9; 415 men) who received educational materials and referrals at 3 month intervals. The primary outcome was the number of significant changes in a cluster of outcomes including HIV-related risks, substance abuse, employment/income, mental health, violence, and community engagement. There was only one significant difference on the rapid diagnostic tests for mandrax at 6 months, an insufficient number of changes to indicate a successful intervention. A group-based behavioral intervention was ineffective in addressing multiple risk behaviors among at-risk young men, similar to the findings of several recent soccer-related interventions. Early adulthood may be too late to alter well-established patterns of risk behaviors.Clinical Trial Registration This trial was prospectively registered on 24 November 2014 with ClinicalTrials.gov NCT02358226.

Keywords: At-risk men; Cluster randomized controlled trial; HIV prevention; Intervention; Soccer; Substance use.

Conflict of interest statement

The authors declare that they have no competing interests.

© 2022. The Author(s).

Figures

Fig. 1
Fig. 1
Participant flow chart, by the soccer league intervention (SL; n = 778) and standard control condition (CC; n = 415)

References

    1. UNAIDS. Global HIV and AIDS statistics 2019 fact sheet. Global HIV AIDS Statistics World AIDS Day [Internet]. 2019; Available from: .
    1. UNAIDS . A snapshot of men and HIV in South Africa. Geneva: UNAIDS; 2017. pp. 1–8.
    1. WHO. Global HIV/AIDS response: epidemic update and health sector progress towards universal access: progress report 2011. 2011. (World Health Organisation). Report No.: 978 92 4 150298 6.
    1. Floyd LJ, Hedden S, Lawson A, Salama C, Moleko AG, Latimer W. The association between poly-substance use, coping, and sex trade among black South African substance users. Subst Use Misuse. 2010;45(12):1971–1987. doi: 10.3109/10826081003767635.
    1. Kalichman SC, Simbayi LC, Kagee A, Toefy Y, Jooste S, Cain D, et al. Associations of poverty, substance use, and HIV transmission risk behaviors in three South African communities. Soc Sci Med. 2006;62(7):1641–1649. doi: 10.1016/j.socscimed.2005.08.021.
    1. Trenz RC, Scherer M, Duncan A, Harrell PT, Moleko AG, Latimer WW. Latent class analysis of polysubstance use, sexual risk behaviors, and infectious disease among South African drug users. Drug Alcohol Depend. 2013;132(3):441–448. doi: 10.1016/j.drugalcdep.2013.03.004.
    1. National Department of Health, ICF. South Africa Demographic and Health Survey 2016 [Internet]. Pretoria: National Department of Health—NDoH—ICF; 2019. Available from: .
    1. World Health Organization . Global status report on alcohol and health 2018. Geneva: World Health Organization; 2019.
    1. Rotheram-Borus MJ, Tomlinson M, Durkin A, Baird K, DeCelles J, Swendeman D. Feasibility of using soccer and job training to prevent drug abuse and HIV. AIDS Behav. 2016;20(9):1841–1850. doi: 10.1007/s10461-015-1262-0.
    1. Swendeman D, Bantjes J, Mindry D, Stewart J, Tomlinson M, Rotheram-Borus MJ, et al. The experiences of young men, their families, and their coaches following a soccer and vocational training intervention to prevent HIV and drug abuse in South Africa. AIDS Educ Prev. 2019;31(3):224–236. doi: 10.1521/aeap.2019.31.3.224.
    1. Bhana D, Pattman R. Researching South African youth, gender and sexuality within the context of HIV/AIDS. Development. 2009;52(1):68–74. doi: 10.1057/dev.2008.75.
    1. Kalichman SC, Simbayi LC. Multiple-recent sexual partnerships and alcohol use among sexually transmitted infection clinic patients, Cape Town South Africa. Sex Transm Dis. 2011;38(1):18–18. doi: 10.1097/OLQ.0b013e3181e77cdd.
    1. Seedat M, Van Niekerk A, Jewkes R, Suffla S, Ratele K. Violence and injuries in South Africa: prioritising an agenda for prevention. Lancet. 2009;374(9694):1011–1022. doi: 10.1016/S0140-6736(09)60948-X.
    1. Intentional homicides, male (per 100,000 male)—South Africa | Data [Internet]. [cited 2022 May 3]. Available from: .
    1. Groenewald P, Bradshaw D, Daniels J, Matzopoulos R, Bourne D, Blease D, et al. Cause of death and premature mortality in Cape Town, 2001–2006. Cape Town: South African Medical Research Council; 2008.
    1. Parry CDH, Plüddemann A, Steyn K, Bradshaw D, Norman R, Laubscher R. Alcohol use in South Africa: findings from the first Demographic and Health Survey (1998) J Stud Alcohol. 2005;66(1):91–97. doi: 10.15288/jsa.2005.66.91.
    1. Reddy S, James S, Sewpaul R, Koopman F, Funani N, Sifunda S, et al. The South African Youth Risk Behaviour Survey 2008—Umthente Uhlaba Usamila. 2010. (South African Medical Research Council). Report No.: 9781920014704.
    1. Harris B, Goudge J, Ataguba JE, McIntyre D, Nxumalo N, Jikwana S, et al. Inequities in access to health care in South Africa. J Public Health Policy. 2011;32(1):S102–S123. doi: 10.1057/jphp.2011.35.
    1. Pienaar K. Rethinking the poverty-disease Nexus: the case of HIV/AIDS in South Africa. J Med Humanit. 2017;38(3):249–266. doi: 10.1007/s10912-015-9369-x.
    1. Karim AQ, Baxter C, Birx D. Prevention of HIV in adolescent girls and young women: key to an AIDS-free generation. JAIDS. 2017;75:S17–S26.
    1. Schaefer S, Gregson S, Fearon E, Hensen B, Hallett T, Hargreaves B. HIV prevention cascades: a unifying framework to replicate the successes of treatment cascades. Lancet HIV. 2019;6(1):e60–e66. doi: 10.1016/S2352-3018(18)30327-8.
    1. Mills EJ, Beyrer C, Birungi J, Dybul MR. Engaging men in prevention and care for HIV/AIDS in Africa. PLoS Med. 2012;9:e1001167. doi: 10.1371/journal.pmed.1001167.
    1. Grossman CI, Purcell DW, Rotheram-Borus MJ, Veniegas R. Opportunities for HIV combination prevention to reduce racial and ethnic health disparities. Am Psychol. 2013;68(4):237. doi: 10.1037/a0032711.
    1. Novak JR, Peak T, Gast J, Arnell M. Associations between masculine norms and health-care utilization in highly religious, heterosexual men. Am J Mens Health. 2019 doi: 10.1177/1557988319856739.
    1. Rotheram-Borus MJ, Tomlinson M, Mayekiso A, Bantjes J, Harris DM, Stewart J, et al. Gender-specific HIV and substance abuse prevention strategies for South African men: study protocol for a randomized controlled trial. Trials. 2018;19(1):1–13. doi: 10.1186/s13063-018-2804-3.
    1. Taylor SE. Tend and befriend: biobehavioral bases of affiliation under stress. Curr Dir Psychol Sci. 2006;15(6):273–277. doi: 10.1111/j.1467-8721.2006.00451.x.
    1. Sewpaul V. On national identity, nationalism and Soccer 2010: should social work be concerned? Int Soc Work. 2009;52(2):143–153. doi: 10.1177/0020872808099726.
    1. Lee J, Macdonald D, Wright J. Young men’s physical activity choices: the impact of capital, masculinities, and location. J Sport Soc Issues. 2009;33(1):59–77. doi: 10.1177/0193723508328904.
    1. Rotheram-Borus MJ, Swendeman D, Becker KD. Adapting evidence-based interventions using a common theory, practices, and principles. J Clin Child Adolesc Psychol. 2014;43(2):229–243. doi: 10.1080/15374416.2013.836453.
    1. Seekings J. Economy, society and municipal services in Khayelitsha. Report for the Commission of Inquiry into Allegations of Police Inefficiency in Khayelitsha and a breakdown in relations between the community and the police in Khayelitsha. Cape Town: University of Cape Town; 2013.
    1. Western Cape Government . Socio-Economic Profile (SEP): city of Cape Town. Cape Town: Western Cape Government; 2016.
    1. O’Reilly KR, Higgins DL. AIDS community demonstration projects for HIV prevention among hard-to-reach groups. Public Health Rep. 1991;106(6):714–720.
    1. Rotheram-Borus MJ, Swendeman D, Chorpita BF. Disruptive innovations for designing and diffusing evidence-based interventions. Am Psychol. 2012;67(6):463–476. doi: 10.1037/a0028180.
    1. Rotheram-Fuller E, Swendeman D, Becker K, Daleiden E, Chorpita B, Youssef MK, et al. Adapting current strategies to implement evidence-based prevention programs for paraprofessional home visiting. Prev Sci. 2017;18(5):590–599. doi: 10.1007/s11121-017-0787-z.
    1. Tsai AC, Tomlinson M, Comulada WS, Rotheram-Borus MJ. Food insufficiency, depression, and the modifying role of social support: evidence from a population-based, prospective cohort of pregnant women in peri-urban South Africa. Soc Sci Med. 2016;151:69–77. doi: 10.1016/j.socscimed.2015.12.042.
    1. Higgins-Biddle JC, Babor T. A review of the Alcohol Use Disorders Identification Test (AUDIT), AUDIT-C, and USAUDIT for screening in the United States: past issues and future directions. Am J Drug Alcohol Abuse. 2018;44(6):578–586. doi: 10.1080/00952990.2018.1456545.
    1. Radloff LS. The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1(3):385–401. doi: 10.1177/014662167700100306.
    1. Tomlinson M, Rotheram-Borus MJ, Le Roux IM, Youssef M, Nelson SH, Scheffler A, et al. Thirty-six-month outcomes of a generalist paraprofessional perinatal home visiting intervention in South Africa on maternal health and child health and development. Prev Sci. 2016;17(8):937–948. doi: 10.1007/s11121-016-0676-x.
    1. Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983;24:385–396. doi: 10.2307/2136404.
    1. AMFORI. Environmental hotspots in the South African Wine Industry. Brussels, Belgium: amfori Sustainable Wine Programme; 2019. p. 1–4.
    1. Martinez P, Lien L, Landheim A, Kowal P, Clausen T. Quality of life and social engagement of alcohol abstainers and users among older adults in South Africa. BMC Public Health. 2014;14(1):1–8. doi: 10.1186/1471-2458-14-316.
    1. Peltzer K, Ramlagan S, Johnson BD, Phaswana-Mafuya N. Illicit drug use and treatment in South Africa: a review. Subst Use Misuse. 2010;45(13):2221–2243. doi: 10.3109/10826084.2010.481594.
    1. Rotheram-Borus MJ, Rabie S, Almirol E, Stewart J, Bantjes J, Tomlinson M. Alcohol’s influence on the 6-month efficacy of an HIV prevention, South African Soccer Program. In: Society for prevention research; 2020.
    1. Abdul-Quader AS, Collins C. Identification of structural interventions for HIV/AIDS prevention: the concept mapping exercise. Public Health Reports. 2011;126(6):777–788. doi: 10.1177/003335491112600603.
    1. Adimora AA, Auerbach JD. Structural interventions for HIV prevention in the United States. J Acquir Immune Defic Syndr. 2010;55(02):S132. doi: 10.1097/QAI.0b013e3181fbcb38.
    1. Dishion TJ, McCord J, Poulin F. When interventions harm: peer groups and problem behavior. Am Psychol. 1999;54(9):755–764. doi: 10.1037/0003-066X.54.9.755.
    1. Lee NK, Rawson RA. A systematic review of cognitive and behavioural therapies for methamphetamine dependence. Drug Alcohol Rev. 2008;27(3):309–317. doi: 10.1080/09595230801919494.
    1. Courtney KE, Ray LA. Methamphetamine: an update on epidemiology, pharmacology, clinical phenomenology, and treatment literature. Drug Alcohol Depend. 2014;143:11–21. doi: 10.1016/j.drugalcdep.2014.08.003.
    1. Baicy K, London ED. Corticolimbic dysregulation and chronic methamphetamine abuse. Addiction. 2007;102:5–15. doi: 10.1111/j.1360-0443.2006.01777.x.
    1. Karila L, Weinstein A, Aubin HJ, Benyamina A, Reynaud M, Batki SL. Pharmacological approaches to methamphetamine dependence: a focused review. Br J Clin Pharmacol. 2010;69(6):578–592. doi: 10.1111/j.1365-2125.2010.03639.x.
    1. Murray L, Kane J, Glass N, van Wyck SS, Melendez F, et al. Effectiveness of the Common Elements Treatment Approach (CETA) in reducing intimate partner violence and hazardous alcohol use in Zambia (VATU): a randomized controlled trial. Plos Med. 2020 doi: 10.1371/journal.pmed.1003056.
    1. Reider EE, Robertson EB, Sims BE. Does early intervention prevent health-risking sexual behaviors related to HIV/AIDS? Prev Sci. 2014;15(1):1–5. doi: 10.1007/s11121-013-0455-x.
    1. Bailey JA. Addressing common risk and protective factors can prevent a wide range of adolescent risk behaviors. J Adolesc Health. 2009;45(2):107–108. doi: 10.1016/j.jadohealth.2009.05.007.
    1. UNAIDS. Ending the AIDS epidemic for adolescents, with adolescents. 2016. .
    1. le Roux IM, Tomlinson M, Harwood JM, O’Connor MJ, Worthman CM, Mbewu N, Stewart J, Hartley M, Swendeman D, Comulada WS, Weiss RE, Rotheram-Borus MJ. Outcomes of home visits for pregnant mothers and their infants: a cluster randomized controlled trial. AIDS. 2013;27(9):1461–1471. doi: 10.1097/QAD.0b013e3283601b53.
    1. Rotheram-Borus MJ, Fernandez MI, Lee S-J, Abdalian SE, Kozina L, Koussa M, Comulada WS, Klausner J, Arnold EM, Ocasio MA, Swendeman D, Adolescent Medicine Trials Network (ATN) CARES Team Strategies to treat and prevent HIV in the United States for adolescents and young adults: a protocol for a mixed methods study. J Med Internet Res. 2019;8(1):e10759. doi: 10.2196/10759.
    1. Richter L, Rotheram-Borus MJ, van Heerden A, Stein A, Tomlinson M, Harwood JM, Rochat T, Van Rooyen H, Comulada S, Tang Z. Pregnant women living with HIV (WLH) supported at clinics by peer WLH: a cluster randomized controlled trial. AIDS Behav. 2014;18(4):706–715. doi: 10.1007/s10461-014-0694-2.
    1. Chorpita BF, Weisz JR, Daleiden EL, Schoenwald SK, Palinkas LA, Miranda J, Higa-McMillan CK, Nakamura BJ, Austin AA, Borntrager CF, Ward A, Wells KC, Gibbons RD, Research Network on Youth Mental Health Long-term outcomes for the Child STEPs randomized effectiveness trial: a comparison of modular and standard treatment designs with usual care. J Consult Clin Psychol. 2013;81(6):999–1009. doi: 10.1037/a0034200.
    1. Smith MA, Lynch WJ. Exercise as a potential treatment for drug abuse: evidence from preclinical studies. Front Psychiatry. 2012;2:82–82. doi: 10.3389/fpsyt.2011.00082.
    1. Field T, Diego M, Sanders CE. Exercise is positively related to adolescents’ relationships and academics. Adolescence. 2001;36(141):105–105.
    1. Kaufman ZA, Spencer TS, Ross DA. Effectiveness of sport-based HIV prevention interventions: a systematic review of the evidence. AIDS Behav. 2013;17(3):987–1001. doi: 10.1007/s10461-012-0348-1.
    1. Hershow RB, Gannett K, Merrill J, Kaufman EB, Barkley C, DeCelles J, et al. Using soccer to build confidence and increase HCT uptake among adolescent girls: a mixed-methods study of an HIV prevention programme in South Africa. Sport Soc. 2015;18(8):1009–1022. doi: 10.1080/17430437.2014.997586.
    1. Balfour L, Farrar T, McGilvray M, Wilson D, Tasca GA, Spaans JN, et al. HIV prevention in action on the football field: the WhizzKids United program in South Africa. AIDS Behav. 2013;17(6):2045–2052. doi: 10.1007/s10461-013-0448-6.
    1. Maleka E, Schneider H, De Coning C, Keim M. Monitoring and evaluation of sports as a tool in HIV/AIDS awareness programmes: experiences of five selected Non-Governmental Organisations in South Africa. Afr J Phys Act Health Sci. 2017;2017(suppl1_2):227–241.
    1. Delva W, Michielsen K, Meulders B, Groeninck S, Wasonga E, Ajwang P, et al. HIV prevention through sport: the case of the Mathare Youth Sport Association in Kenya. AIDS Care. 2010;22(8):1012–1020. doi: 10.1080/09540121003758606.
    1. Melendez-Torres GJ, Spencer T, Ingram L, Zimmerman RS, Pettengill R, Mullman M, et al. Quasi-experimental evaluation of The Grassroot Project, a sport-based sexual health promotion program for urban middle school students. Am J Sex Educ. 2020;15(4):465–475.
    1. Vrana-Diaz CJ, Stevens DR, Ndeche E, Korte JE. HIV self-testing knowledge and attitudes at sports-based HIV prevention tournaments in Nairobi, Kenya. J HIV/AIDS Soc Serv. 2019;18(2):180–196. doi: 10.1080/15381501.2019.1620663.
    1. Kaufman ZA, Kaufman EB, Dringus S, Weiss HA, Delany-Moretlwe S, Ross DA. Baseline results of a cluster-randomised trial assessing the effectiveness of sport-based HIV prevention in South African schools. Sex Transm Infect. 2013;89(Suppl 1):A268–A268. doi: 10.1136/sextrans-2013-051184.0833.
    1. Kaufman ZA, DeCelles J, Bhauti K, Hershow RB, Weiss HA, Chaibva C, et al. A sport-based intervention to increase uptake of voluntary medical male circumcision among adolescent male students: results from the MCUTS 2 cluster-randomized trial in Bulawayo, Zimbabwe. J Acquir Immune Defic Syndr. 2016;72(Suppl 4):S297. doi: 10.1097/QAI.0000000000001046.

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