Clinical and cost-effectiveness of home-based cardiac rehabilitation compared to conventional, centre-based cardiac rehabilitation: Results of the FIT@Home study
Jos J Kraal, M Elske Van den Akker-Van Marle, Ameen Abu-Hanna, Wim Stut, Niels Peek, Hareld Mc Kemps, Jos J Kraal, M Elske Van den Akker-Van Marle, Ameen Abu-Hanna, Wim Stut, Niels Peek, Hareld Mc Kemps
Abstract
Aim Although cardiac rehabilitation improves physical fitness after a cardiac event, many eligible patients do not participate in cardiac rehabilitation and the beneficial effects of cardiac rehabilitation are often not maintained over time. Home-based training with telemonitoring guidance could improve participation rates and enhance long-term effectiveness. Methods and results We randomised 90 low-to-moderate cardiac risk patients entering cardiac rehabilitation to three months of either home-based training with telemonitoring guidance or centre-based training. Although training adherence was similar between groups, satisfaction was higher in the home-based group ( p = 0.02). Physical fitness improved at discharge ( p < 0.01) and at one-year follow-up ( p < 0.01) in both groups, without differences between groups (home-based p = 0.31 and centre-based p = 0.87). Physical activity levels did not change during the one-year study period (centre-based p = 0.38, home-based p = 0.80). Healthcare costs were statistically non-significantly lower in the home-based group (€437 per patient, 95% confidence interval -562 to 1436, p = 0.39). From a societal perspective, a statistically non-significant difference of €3160 per patient in favour of the home-based group was found (95% confidence interval -460 to 6780, p = 0.09) and the probability that it was more cost-effective varied between 97% and 75% (willingness-to-pay of €0 and €100,000 per quality-adjusted life-years, respectively). Conclusion We found no differences between home-based training with telemonitoring guidance and centre-based training on physical fitness, physical activity level or health-related quality of life. However, home-based training was associated with a higher patient satisfaction and appears to be more cost-effective than centre-based training. We conclude that home-based training with telemonitoring guidance can be used as an alternative to centre-based training for low-to-moderate cardiac risk patients entering cardiac rehabilitation.
Keywords: Cardiac rehabilitation; home-based training; physical activity; physical fitness; telemonitoring.
Figures
References
- Mozaffarian D, Benjamin EJ, Go AS, et al. Heart disease and stroke statistics-2015 update: A report from the American Heart Association. Circulation 2015; 131: e29–e322.
- Goel K, Lennon RJ, Tilbury RT, et al. Impact of cardiac rehabilitation on mortality and cardiovascular events after percutaneous coronary intervention in the community. Circulation 2011; 123: 2344–2352.
- Vries H de, Kemps HMC, van Engen-Verheul MM, et al. Cardiac rehabilitation and survival in a large representative community cohort of Dutch patients. Eur Heart J 2015; 36: 1–10.
- Steg PG, James SK, Atar D, et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J 2012; 33: 2569–2619.
- Anderson L, Oldridge N, Thompson DR, et al. Exercise-based cardiac rehabilitation for coronary heart disease. J Am Coll Cardiol 2016; 67: 1–12.
- Müller-Riemenschneider F, Meinhard C, Damm K, et al. Effectiveness of nonpharmacological secondary prevention of coronary heart disease. Eur J Cardiovasc Prev Rehabil 2010; 17: 688–700.
- Neubeck L, Ben Freedman S, Clark AM, et al. Participating in cardiac rehabilitation: A systematic review and meta-synthesis of qualitative data. Eur J Cardiovasc Prev Rehabil 2011; 19: 494–503.
- Vos C De, Li X, Van Vlaenderen I, et al. Participating or not in a cardiac rehabilitation programme: Factors influencing a patient’s decision. Eur J Prev Cardiol 2013; 20: 341–348.
- Cowie A, Thow MK, Granat MH, et al. A comparison of home and hospital-based exercise training in heart failure: Immediate and long-term effects upon physical activity level. Eur J Cardiovasc Prev Rehabil 2011; 18: 158–166.
- Yu C-M, Li LS-W, Ho H, et al. Long-term changes in exercise capacity, quality of life, body anthropometry, and lipid profiles after a cardiac rehabilitation program in obese patients with coronary heart disease. Am J Cardiol 2003; 91: 321–325.
- Lee IM, Shiroma EJ, Lobelo F, et al. Effect of physical inactivity on major non-communicable diseases worldwide: An analysis of burden of disease and life expectancy. Lancet 2012; 380: 219–229.
- Brubaker PH, Warner JG, Jr, Rejeski WJ, et al. Comparison of standard- and extended-length participation in cardiac rehabilitation on body composition, functional capacity, and blood lipids. Am J Cardiol 1996; 78: 769–773.
- Bock BC, Carmona-Barros RE, Esler JL, et al. Program participation and physical activity maintenance after cardiac rehabilitation. Behav Modif 2003; 27: 37–53.
- Vanhees L, Lefevre J, Philippaerts R, et al. How to assess physical activity? How to assess physical fitness? Eur J Cardiovasc Prev Rehabil 2005; 12: 102–114.
- Taylor RS, Dalal H, Jolly K, et al. Home-based versus centre-based cardiac rehabilitation. Cochrane Database Syst Rev 2015; 8: CD007130–CD007130.
- Oerkild B, Frederiksen M, Hansen JF, et al. Home-based cardiac rehabilitation is an attractive alternative to no cardiac rehabilitation for elderly patients with coronary heart disease: Results from a randomised clinical trial. BMJ Open 2012; 2: 1–9.
- Izawa KP, Watanabe S, Omiya K, et al. Effect of the self-monitoring approach on exercise maintenance during cardiac rehabilitation. Am J Phys Med Rehabil 2005; 84: 313–321.
- Reid RD, Morrin LI, Beaton LJ, et al. Randomized trial of an internet-based computer-tailored expert system for physical activity in patients with heart disease. Eur J Prev Cardiol 2012; 19: 1357–1364.
- Frederix I, Van Driessche N, Hansen D, et al. Increasing the medium-term clinical benefits of hospital-based cardiac rehabilitation by physical activity telemonitoring in coronary artery disease patients. Eur J Prev Cardiol 2015; 2: 150–158.
- Woodgate J, Brawley LR. Self-efficacy for exercise in cardiac rehabilitation: Review and recommendations. J Health Psychol 2008; 13: 366–387.
- Lorig KR, Holman HR. Self-management education: History definition, outcomes and mechanisms. Ann Behav Med 2003; 26: 1–7.
- Rodgers WM, Murray TC, Selzler A-M, et al. Development and impact of exercise self-efficacy types during and after cardiac rehabilitation. Rehabil Psychol 2013; 58: 178–184.
- Kraal JJ, Peek N, van den Akker-Van Marle ME, et al. Effects and costs of home-based training with telemonitoring guidance in low to moderate risk patients entering cardiac rehabilitation: The FIT@Home study. BMC Cardiovasc Disord 2013; 13: 82–82.
- Commissie Cardiovasculaire Preventie en Hartrevalidatie. Nederlandse Vereniging Voor Cardiologie Praktijkrichtlijn hartrevalidatie maart 2011, Utrecht: Ned. Ver. voor Cardiol, 2011.
- Rehabilitation Committee (Nederlandse Vereniging Voor Cardiologie/Nederlandse Hartstichting) and working group Psychische en Arbeidsgerelateerde Aspecten van HartRevalidatie (PAAHR). Multidisciplinary guidelines for cardiac rehabilitation hartrevalidatie 2011. Utrecht: Netherlands Society for Cardiology, 2011.
- Piepoli MF, Corrà U, Benzer W, et al. Secondary prevention through cardiac rehabilitation: From knowledge to implementation. A position paper from the Cardiac Rehabilitation Section of the European Association of Cardiovascular Prevention and Rehabilitation. Eur J Cardiovasc Prev Rehabil 2010; 17: 1–17.
- Beaver WL, Wasserman K, Whipp BJ. A new method for detecting anaerobic threshold by gas exchange A new method for detecting threshold by gas exchange anaerobic. J Appl Physiol 1986; 60: 2020–2027.
- Harris J, Benedict FG. A biometric study of human basal metabolism. Proc Natl Acad Sci 1918; 4: 370–373.
- Kraal JJ, Sartor F, Papini G, et al. Energy expenditure estimation in beta-blocker-medicated cardiac patients by combining heart rate and body movement data. Eur J Prev Cardiol 2016; 23: 1734–1742.
- Whaley MH, Brubaker PH, Otto RM, et al. ACSM’s guidelines for exercise testing and prescription, 7th ed Philadelphia, PA: Lippincott Williams & Wilkins, 2006.
- Black AE, Coward WA, Cole TJ. Human energy expenditure in affluent societies: An analysis of 574 doubly-labelled water measurements. Eur J Clin Nutr 1996; 50: 72–92.
- Brazier JE, Roberts J. The estimation of a preference-based measure of health from the SF-12. Med Care 2004; 42: 851–859.
- De Gucht V, Van Elderen T, van der Kamp L, et al. Quality of life after myocardial infarction: Translation and validation of the MacNew Questionnaire for a Dutch population. Qual Life Res 2004; 13: 1483–1488.
- Delnoij DMJ, Rademakers JJDJM, Groenewegen PP. The Dutch consumer quality index: An example of stakeholder involvement in indicator development. BMC Health Serv Res 2010; 10: 88–88.
- Stafford L, Berk M, Jackson HJ. Validity of the Hospital Anxiety and Depression Scale and Patient Health Questionnaire-9 to screen for depression in patients with coronary artery disease. Gen Hosp Psychiatry 2007; 29: 417–424.
- Hakkaart-van Roijen L, Tan SS and Bouwmans CAM. Handleiding voor kostenonderzoek, methoden en standaard kostprijzen voor economische evaluaties in de gezondheidszorg. Coll. voor zorgverzekeringen, geactualiseerde versie, Diemen, 2010.
- Statistics Netherlands. Consumer price index, (2015, accessed 1 December 2015).
- Zorginstituut Nederland, (2015, accessed 1 December 2015).
- Koopmanschap M, Rutten FFH, Van Ineveld BM, et al. The friction cost method for measuring indirect costs of disease. J Health Econ 1995; 6: 171–189.
- Bonomi AG, Plasqui G, Goris AHC, et al. Estimation of free-living energy expenditure using a novel activity monitor designed to minimize obtrusiveness. Obesity 2010; 18: 1845–1851.
- Van der Heijden GJ, Donders AR, Stijnen T, et al. Imputation of missing values is superior to complete case analysis and the missing-indicator method in multivariable diagnostic research: A clinical example. J Clin Epidemiol 2006; 59: 1102–1109.
- Thompson SG, Barber J. How should cost data in pragmatic randomised trials be analysed? Br Med J 2000; 320: 1197–1200.
- Bobinac A, Van Exel NJA, Rutten FFH, et al. Willingness to pay for a quality-adjusted life-year: The individual perspective. Value Health 2010; 13: 1046–1055.
- Aamot IL, Karlsen T, Dalen H, et al. Long-term exercise adherence after high-intensity interval training in cardiac rehabilitation: A randomized study. Physiother Res Int 2016; 21: 1070–1078.
- Smith KM, McKelvie RS, Thorpe KE, et al. Six-year follow-up of a randomised controlled trial examining hospital versus home-based exercise training after coronary artery bypass graft surgery. Heart 2011; 97: 1169–1174.
- Cowie A, Thow MK, Granat MH, et al. A comparison of home and hospital-based exercise training in heart failure: Immediate and long-term effects upon physical activity level. Eur J Cardiovasc Prev Rehabil 2011; 18: 158–166.
- Borland M, Rosenkvist A, Cider A. A group-based exercise program did not improve physical activity in patients with chronic heart failure and comorbidity: A randomized controlled trial. J Rehabil Med 2014; 46: 461–467.
- Ter Hoeve N, Huisstede BMA, Stan JH, et al. Does cardiac rehabilitation after an acute cardiac syndrome lead to changes in physical activity habits? Systematic Review. Phys Ther 2015; 95: 167–179.
- Oliveira J, Ribeiro F, Gomes H. Effects of a home-based cardiac rehabilitation program on the physical activity levels of patients with coronary artery disease. J Cardiopulm Rehabil Prev 2008; 28: 392–396.
- Chase JA. Systematic review of physical activity intervention studies after cardiac rehabilitation. J Cardiovasc Nurs 2011; 26: 351–358.
- Kaminsky LA, Brubaker PH, Guazzi M, et al. Assessing physical activity as a core component in cardiac rehabilitation. J Cardiopulm Rehabil Prev 2016; 36: 217–229.
- Brage S, Brage N, Franks PW, et al. Branched equation modeling of simultaneous accelerometry and heart rate monitoring improves estimate of directly measured physical activity energy expenditure. J Appl Physiol 2004; 96: 343–351.
- Frederix I, Hansen D, Coninx K, et al. Effect of comprehensive cardiac telerehabilitation on one-year cardiovascular rehospitalization rate, medical costs and quality of life: A cost-effectiveness analysis. Eur J Prev Cardiol 2016; 23: 674–682.
- Kidholm K, Rasmussen MK, Andreasen JJ, et al. Cost-utility analysis of a cardiac telerehabilitation program: The Teledialog Project. Telemed J E Health 2016; 22: 553–563.
Source: PubMed