Obstructive sleep apnea among obese patients with type 2 diabetes

Gary D Foster, Mark H Sanders, Richard Millman, Gary Zammit, Kelley E Borradaile, Anne B Newman, Thomas A Wadden, David Kelley, Rena R Wing, F Xavier Pi Sunyer, Valerie Darcey, Samuel T Kuna, Sleep AHEAD Research Group, Gary D Foster, Mark H Sanders, Richard Millman, Gary Zammit, Kelley E Borradaile, Anne B Newman, Thomas A Wadden, David Kelley, Rena R Wing, F Xavier Pi Sunyer, Valerie Darcey, Samuel T Kuna, Sleep AHEAD Research Group

Abstract

Objective: To assess the risk factors for the presence and severity of obstructive sleep apnea (OSA) among obese patients with type 2 diabetes.

Research design and methods: Unattended polysomnography was performed in 306 participants.

Results: Over 86% of participants had OSA with an apnea-hypopnea index (AHI) >or=5 events/h. The mean AHI was 20.5 +/- 16.8 events/h. A total of 30.5% of the participants had moderate OSA (15 <or= AHI <30), and 22.6% had severe OSA (AHI >or=30). Waist circumference (odds ratio 1.1; 95% CI 1.0-1.1; P = 0.03) was significantly related to the presence of OSA. Severe OSA was most likely in individuals with a higher BMI (odds ratio 1.1; 95% CI 1.0-1.2; P = 0.03).

Conclusions: Physicians should be particularly cognizant of the likelihood of OSA in obese patients with type 2 diabetes, especially among individuals with higher waist circumference and BMI.

Trial registration: ClinicalTrials.gov NCT00194259.

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Source: PubMed

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