Non-alcoholic steatohepatitis: the therapeutic challenge of a global epidemic

Marialena Mouzaki, Johane Allard, Marialena Mouzaki, Johane Allard

Abstract

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. Nonalcoholic steatohepatitis (NASH) reflects severe liver disease within the NAFLD spectrum and can progress to end-stage liver disease. Within this manuscript we review the available evidence for the treatment of NASH as well as the newer therapeutic agents that are currently being investigated.

Keywords: NASH; fatty liver; pioglitazone; treatment; vitamin E.

Conflict of interest statement

Conflict of Interest: None

Figures

Figure 1
Figure 1
Site of action of treatments studied in non-alcoholic steatohepatitis ARB, Angiotensin-II Receptor Blockers; FXR, Farnesoid X Receptor; GLP-1, Glucagon-Like Peptide-1

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