Effects of astaxanthin on human blood rheology

Hiromi Miyawaki, Jiro Takahashi, Hiroki Tsukahara, Isao Takehara, Hiromi Miyawaki, Jiro Takahashi, Hiroki Tsukahara, Isao Takehara

Abstract

Effects of astaxanthin (AX) derived from H. pluvialis on human blood rheology were investigated in 20 adult men with a single-blind method. The experimental group was 57.5 +/- 9.8 years of age and the placebo group was 50.8 +/- 13.1 years of age. A blood rheology test that measures whole blood transit time was conducted using heparinized blood of the volunteers by a MC-FAN apparatus (microchannel array flow analyzer). After administration of AX 6 mg/day for 10 days, the values of the experimental group were decreased from 52.8 +/- 4.9 s to 47.6 +/- 4.2 s (p<0.01) and a comparison of the values between the experimental (47.6 +/- 4.2 s) and the placebo (54.2 +/- 6.7 s) groups showed a significant difference (p<0.05). There were no adverse effects resulting from the administration of AX 6 mg/day for 10 days. Informed consent was obtained from each subject.

Keywords: astaxanthin; blood rheology; blood transit time; male volunteers; microchannel array flow analyzer.

Figures

Fig. 1
Fig. 1
Summary of measurement results for each subject’s blood transit time

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