The cross-national epidemiology of social anxiety disorder: Data from the World Mental Health Survey Initiative

Dan J Stein, Carmen C W Lim, Annelieke M Roest, Peter de Jonge, Sergio Aguilar-Gaxiola, Ali Al-Hamzawi, Jordi Alonso, Corina Benjet, Evelyn J Bromet, Ronny Bruffaerts, Giovanni de Girolamo, Silvia Florescu, Oye Gureje, Josep Maria Haro, Meredith G Harris, Yanling He, Hristo Hinkov, Itsuko Horiguchi, Chiyi Hu, Aimee Karam, Elie G Karam, Sing Lee, Jean-Pierre Lepine, Fernando Navarro-Mateu, Beth-Ellen Pennell, Marina Piazza, Jose Posada-Villa, Margreet Ten Have, Yolanda Torres, Maria Carmen Viana, Bogdan Wojtyniak, Miguel Xavier, Ronald C Kessler, Kate M Scott, WHO World Mental Health Survey Collaborators, Dan J Stein, Carmen C W Lim, Annelieke M Roest, Peter de Jonge, Sergio Aguilar-Gaxiola, Ali Al-Hamzawi, Jordi Alonso, Corina Benjet, Evelyn J Bromet, Ronny Bruffaerts, Giovanni de Girolamo, Silvia Florescu, Oye Gureje, Josep Maria Haro, Meredith G Harris, Yanling He, Hristo Hinkov, Itsuko Horiguchi, Chiyi Hu, Aimee Karam, Elie G Karam, Sing Lee, Jean-Pierre Lepine, Fernando Navarro-Mateu, Beth-Ellen Pennell, Marina Piazza, Jose Posada-Villa, Margreet Ten Have, Yolanda Torres, Maria Carmen Viana, Bogdan Wojtyniak, Miguel Xavier, Ronald C Kessler, Kate M Scott, WHO World Mental Health Survey Collaborators

Abstract

Background: There is evidence that social anxiety disorder (SAD) is a prevalent and disabling disorder. However, most of the available data on the epidemiology of this condition originate from high income countries in the West. The World Mental Health (WMH) Survey Initiative provides an opportunity to investigate the prevalence, course, impairment, socio-demographic correlates, comorbidity, and treatment of this condition across a range of high, middle, and low income countries in different geographic regions of the world, and to address the question of whether differences in SAD merely reflect differences in threshold for diagnosis.

Methods: Data from 28 community surveys in the WMH Survey Initiative, with 142,405 respondents, were analyzed. We assessed the 30-day, 12-month, and lifetime prevalence of SAD, age of onset, and severity of role impairment associated with SAD, across countries. In addition, we investigated socio-demographic correlates of SAD, comorbidity of SAD with other mental disorders, and treatment of SAD in the combined sample. Cross-tabulations were used to calculate prevalence, impairment, comorbidity, and treatment. Survival analysis was used to estimate age of onset, and logistic regression and survival analyses were used to examine socio-demographic correlates.

Results: SAD 30-day, 12-month, and lifetime prevalence estimates are 1.3, 2.4, and 4.0% across all countries. SAD prevalence rates are lowest in low/lower-middle income countries and in the African and Eastern Mediterranean regions, and highest in high income countries and in the Americas and the Western Pacific regions. Age of onset is early across the globe, and persistence is highest in upper-middle income countries, Africa, and the Eastern Mediterranean. There are some differences in domains of severe role impairment by country income level and geographic region, but there are no significant differences across different income level and geographic region in the proportion of respondents with any severe role impairment. Also, across countries SAD is associated with specific socio-demographic features (younger age, female gender, unmarried status, lower education, and lower income) and with similar patterns of comorbidity. Treatment rates for those with any impairment are lowest in low/lower-middle income countries and highest in high income countries.

Conclusions: While differences in SAD prevalence across countries are apparent, we found a number of consistent patterns across the globe, including early age of onset, persistence, impairment in multiple domains, as well as characteristic socio-demographic correlates and associated psychiatric comorbidities. In addition, while there are some differences in the patterns of impairment associated with SAD across the globe, key similarities suggest that the threshold for diagnosis is similar regardless of country income levels or geographic location. Taken together, these cross-national data emphasize the international clinical and public health significance of SAD.

Keywords: Cross-national epidemiology; Social anxiety disorder; Social phobia; World Mental Health Survey Initiative.

Figures

Fig. 1
Fig. 1
Age of onset of SAD by country income level

References

    1. Magee WJ, Eaton WW, Wittchen HU, McGonagle KA, Kessler RC. Agoraphobia, simple phobia, and social phobia in the National Comorbidity Survey. Arch Gen Psychiatry. 1996;53:159–68. doi: 10.1001/archpsyc.1996.01830020077009.
    1. Ruscio AM, Brown TA, Chiu WT, Sareen J, Stein MB, Kessler RC. Social fears and social phobia in the USA: results from the National Comorbidity Survey Replication. Psychol Med. 2008;38:15–28. doi: 10.1017/S0033291707001699.
    1. Kessler RC. The impairments caused by social phobia in the general population: implications for intervention. Acta Psychiatr Scand Suppl. 2003;108:19–27. doi: 10.1034/j.1600-0447.108.s417.2.x.
    1. Kessler RC, Ruscio AM, Shear K, Wittchen HU. Epidemiology of anxiety disorders. Curr Top Behav Neurosci. 2010;2:21–35. doi: 10.1007/7854_2009_9.
    1. Dalrymple KL, Zimmerman M. Screening for social fears and social anxiety disorder in psychiatric outpatients. Compr Psychiatry. 2008;49:399–406. doi: 10.1016/j.comppsych.2008.01.009.
    1. Connor KM, Kobak KA, Churchill LE, Katzelnick D, Davidson JR. Mini-SPIN: a brief screening assessment for generalized social anxiety disorder. Depress Anxiety. 2001;14:137–40. doi: 10.1002/da.1055.
    1. Fehm L, Pelissolo A, Furmark T, Wittchen HU. Size and burden of social phobia in Europe. Eur Neuropsychopharmacol. 2005;15:453–62. doi: 10.1016/j.euroneuro.2005.04.002.
    1. Weissman MM, Bland RC, Canino GJ, Greenwald S, Lee CK, Newman SC, Rubio-Stipec M, Wickramaratne PJ. The cross-national epidemiology of social phobia: a preliminary report. Int Clin Psychopharmacol. 1996;11(Suppl 3):9–14. doi: 10.1097/00004850-199606003-00003.
    1. Dowbiggin IR. High anxieties: the social construction of anxiety disorders. Can J Psychiatry. 2009;54:429–36. doi: 10.1177/070674370905400703.
    1. Data: Countries and Economies. .
    1. Heeringa S, Wells E, Hubbard F, Mneimneh Z, Chiu W, Sampson N, Berglund P. Sample designs and sampling procedures. In: Kessler R, Ustun T, editors. The WHO World Mental Health Surveys: global perspectives on the epidemiology of mental disorders. New York: Cambridge University Press; 2008. pp. 14–32.
    1. Kessler R, Ustun T. The WHO World Mental Health Surveys: global perspectives on the epidemiology of mental disorders. New York: Cambridge University Press; 2008.
    1. Harkness J, Pennell B-E, Villar A, Gebler N, Aguilar-Gaxiola S, Bilgen I. Translation procedures and translation assessment in the World Mental Health Survey Initiative. In: Kessler R, Ustun T, editors. The WHO World Mental Health Surveys: global perspectives on the epidemiology of mental disorders. New York: Cambridge University Press; 2008. pp. 91–113.
    1. Pennell B-E, Mneimneh Z, Bowers A, Chardoul S, Welles J, Viana M, Dinkelmann K, Gebler N, Florescu S, He Y, Huang Y, Tomov T, Vilagut G. Implementation of the World Mental Health Surveys Initiative. In: Kessler R, Ustun T, editors. The WHO World Mental Health Surveys: global perspectives on the epidemiology of mental disorders. New York: Cambridge University Press; 2008. pp. 33–57.
    1. Kessler RC, Ustun TB. The World Mental Health (WMH) Survey Initiative Version of the World Health Organization (WHO) Composite International Diagnostic Interview (CIDI) Int J Methods Psychiatr Res. 2004;13:93–121. doi: 10.1002/mpr.168.
    1. Knäuper B, Cannell C, Schwarz N, Bruce M, Kessler R. Improving accuracy of major depression age-of-onset reports in the US National Comorbidity Survey. Int J Methods Psychiatr Res. 1999;8:39–48. doi: 10.1002/mpr.55.
    1. First MB, Spitzer RL, Gibbon M, Williams BJ. Structured Clinical Interview for Axis I DSM-IV Disorders. New York: Biometrics Research, New York State Psychiatric Institute; 1994.
    1. Haro JM, Arbabzadeh-Bouchez S, Brugha TS, de Girolamo G, Guyer ME, Jin R, Lepine JP, Mazzi F, Reneses B, Vilagut G, Sampson NA, Kessler RC. Concordance of the Composite International Diagnostic Interview Version 3.0 (CIDI 3.0) with standardized clinical assessments in the WHO World Mental Health surveys. Int J Methods Psychiatr Res. 2006;15:167–80. doi: 10.1002/mpr.196.
    1. Sheehan DV, Harnett-Sheehan K, Raj BA. The measurement of disability. Int Clin Psychopharmacol. 1996;11(Suppl 3):89–95. doi: 10.1097/00004850-199606003-00015.
    1. Levinson D, Lakoma MD, Petukhova M, Schoenbaum M, Zaslavsky AM, Angermeyer M, Borges G, Bruffaerts R, de Girolamo G, de Graaf R, Gureje O, Haro JM, Hu C, Karam AN, Kawakami N, Lee S, Lepine JP, Browne MO, Okoliyski M, Posada-Villa J, Sagar R, Viana MC, Williams DR, Kessler RC. Associations of serious mental illness with earnings: results from the WHO World Mental Health surveys. Br J Psychiatry. 2010;197:114–21. doi: 10.1192/bjp.bp.109.073635.
    1. Wolter K. Introduction to variance estimation. New York: Springer-Verlag; 1985.
    1. Institute RT . SUDAAN: Professional Software for Survey Data Analysis. Research Triangle Park: Research Triangle Institute; 2002.
    1. Riley J. Estimates of regional and global life expectancy, 1800-2001. Popul Dev Rev. 2005;31:537–43. doi: 10.1111/j.1728-4457.2005.00083.x.
    1. Stein DJ. Social anxiety disorder in the West and in the East. Ann Clin Psychiatry. 2009;21:109–17.
    1. Stein DJ, Matsunaga H. Cross-cultural aspects of social anxiety disorder. Psychiatr Clin North Am. 2001;24:773–82. doi: 10.1016/S0193-953X(05)70262-8.
    1. Lewis-Fernandez R, Hinton DE, Laria AJ, Patterson EH, Hofmann SG, Craske MG, Stein DJ, Asnaani A, Liao B. Culture and the anxiety disorders: recommendations for DSM-V. Depress Anxiety. 2010;27:212–29. doi: 10.1002/da.20647.
    1. Hofmann SG, Anu Asnaani MA, Hinton DE. Cultural aspects in social anxiety and social anxiety disorder. Depress Anxiety. 2010;27:1117–27. doi: 10.1002/da.20759.
    1. Dixon LJ, Tull MT, Lee AA, Kimbrel NA, Gratz KL. The role of emotion-driven impulse control difficulties in the relation between social anxiety and aggression. J Clin Psychol. 2017;73:722–32. doi: 10.1002/jclp.22372.
    1. Neumann ID, Veenema AH, Beiderbeck DI. Aggression and anxiety: social context and neurobiological links. Front Behav Neurosci. 2010;4:12.

Source: PubMed

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