Epidemiology of gynecologic cancers in China

Xiyi Jiang, Huijuan Tang, Tianhui Chen, Xiyi Jiang, Huijuan Tang, Tianhui Chen

Abstract

Cancer has become a major disease burden across the globe. It was estimated that 4.29 million new incident cases and 2.81 million death cases of cancer would occur in 2015 in China, with the age-standardized incidence rate (ASIR) of 201.1 per 100,000 and age-standardized mortality rate (ASMR) of 126.9 per 100,000, respectively. For females, 2 of the top 10 most common types of cancer would be gynecologic cancers, with breast cancer being the most prevalent (268.6 thousand new incident cases) and cervical cancer being the 7th most common cancer (98.9 thousand new incident cases). The incidence and mortality of gynecologic cancers have been constantly increasing in China over last 2 decades, which become a major health concern for women. Survival rates of gynecologic cancers are generally not satisfactory and decrease along with advancing stage, though national data on survival are still not available. It is of great importance to overview on the epidemiology of gynecologic cancers, which may provide scientific clues for strategy-making of prevention and control, and eventually lowering the incidence and mortality rate as well as improving the survival rate in the future.

Keywords: China; Epidemiology; Genital Neoplasms, Female; Incidence; Mortality; Survival.

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Copyright © 2018. Asian Society of Gynecologic Oncology, Korean Society of Gynecologic Oncology.

Figures

Fig. 1
Fig. 1
Ten most common cancers in women in 2015 in China (estimated).
Fig. 2
Fig. 2
Trends in incidence rates of 4 major gynecologic cancers in China: (A) cervical cancer, (B) endometrial cancer, (C) ovarian cancer, and (D) breast cancer.
Fig. 3
Fig. 3
Five-year relative survival rates of 4 major gynecologic cancers in China.

References

    1. Chen W, Zheng R, Zeng H, Zhang S, He J. Annual report on status of cancer in China, 2011. Chin J Cancer Res. 2015;27:2–12.
    1. Zheng R, Zeng H, Zhang S, Chen T, Chen W. National estimates of cancer prevalence in China, 2011. Cancer Lett. 2016;370:33–38.
    1. Chen W, Zheng R, Baade PD, Zhang S, Zeng H, Bray F, et al. Cancer statistics in China, 2015. CA Cancer J Clin. 2016;66:115–132.
    1. National Bureau of Statistics of China. China statistical yearbook 2010. Beijing: China Statistics Press; 2010.
    1. Hu SY, Zheng RS, Zhao FH, Zhang SW, Chen WQ, Qiao YL. Trend analysis of cervical cancer incidence and mortality rates in Chinese women during 1989–2008. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2014;36:119–125.
    1. Chen W, Zheng R, Zhang S, Zeng H, Xia C, Zuo T, et al. Cancer incidence and mortality in China, 2013. Cancer Lett. 2017;401:63–71.
    1. Liu X, Feng A, Cui Y, Tobe RG. Prevention of human papillomavirus (HPV) infection and cervical cancer in China: how does HPV vaccination bring about benefits to Chinese women? Biosci Trends. 2013;7:159–167.
    1. Li S, Hu T, Lv W, Zhou H, Li X, Yang R, et al. Changes in prevalence and clinical characteristics of cervical cancer in the People's Republic of China: a study of 10,012 cases from a nationwide working group. Oncologist. 2013;18:1101–1107.
    1. Zhao FH, Lewkowitz AK, Hu SY, Chen F, Li LY, Zhang QM, et al. Prevalence of human papillomavirus and cervical intraepithelial neoplasia in China: a pooled analysis of 17 population-based studies. Int J Cancer. 2012;131:2929–2938.
    1. Wang R, Guo XL, Wisman GB, Schuuring E, Wang WF, Zeng ZY, et al. Nationwide prevalence of human papillomavirus infection and viral genotype distribution in 37 cities in China. BMC Infect Dis. 2015;15:257.
    1. Zeng H, Zheng R, Guo Y, Zhang S, Zou X, Wang N, et al. Cancer survival in China, 2003–2005: a population-based study. Int J Cancer. 2015;136:1921–1930.
    1. Cheung FY, Mang OW, Law SC. A population-based analysis of incidence, mortality, and stage-specific survival of cervical cancer patients in Hong Kong: 1997–2006. Hong Kong Med J. 2011;17:89–95.
    1. Wernli KJ, Ray RM, Gao DL, De Roos AJ, Checkoway H, Thomas DB. Menstrual and reproductive factors in relation to risk of endometrial cancer in Chinese women. Cancer Causes Control. 2006;17:949–955.
    1. Gao J, Yang G, Wen W, Cai QY, Zheng W, Shu XO, et al. Impact of known risk factors on endometrial cancer burden in Chinese women. Eur J Cancer Prev. 2016;25:329–334.
    1. Huang CY, Chen CA, Chen YL, Chiang CJ, Hsu TH, Lin MC, et al. Nationwide surveillance in uterine cancer: survival analysis and the importance of birth cohort: 30-year population-based registry in Taiwan. PLoS One. 2012;7:e51372.
    1. Salehi F, Dunfield L, Phillips KP, Krewski D, Vanderhyden BC. Risk factors for ovarian cancer: an overview with emphasis on hormonal factors. J Toxicol Environ Health B Crit Rev. 2008;11:301–321.
    1. Zhang S, Xia Q, Zheng R, Chen W. Incidence and mortality of ovarian cancer in China, 2010. China Cancer. 2016;25:169–173.
    1. Wong KH, Mang OW, Au KH, Law SC. Incidence, mortality, and survival trends of ovarian cancer in Hong Kong, 1997 to 2006: a population-based study. Hong Kong Med J. 2012;18:466–474.
    1. Chen WQ, Zheng RS, Zeng HM, Zhang SW, Zhao P, He J. Trend analysis and projection of cancer incidence in China between 1989 and 2008. Zhonghua Zhong Liu Za Zhi. 2012;34:517–524.
    1. Li L, Ji J, Wang JB, Niyazi M, Qiao YL, Boffetta P. Attributable causes of breast cancer and ovarian cancer in china: reproductive factors, oral contraceptives and hormone replacement therapy. Chin J Cancer Res. 2012;24:9–17.
    1. Zeng HM, Zheng RS, Zhang SW, Zhao P, He J, Chen WQ. Trend analysis of cancer mortality in China between 1989 and 2008. Zhonghua Zhong Liu Za Zhi. 2012;34:525–531.
    1. Su Y, Zheng Y, Zheng W, Gu K, Chen Z, Li G, et al. Distinct distribution and prognostic significance of molecular subtypes of breast cancer in Chinese women: a population-based cohort study. BMC Cancer. 2011;11:292.

Source: PubMed

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