Research Tech IV-XTAL

At ICON, it’s our people that set us apart. Our diverse teams enable us to become a better partner to our customers and help us to fulfil our mission to advance and improve patients’ lives.Our ‘Own It’ culture is driven by four key values that bring us together as individuals and set us apart as an organisation: Accountability & Delivery, Collaboration, Partnership and Integrity. We want to be the Clinical Research Organisation that delivers excellence to our clients and to patients at every touch-point. In short, to be the partner of choice in drug development.That’s our vision. We’re driven by it. And we need talented people who share it.If you’re as driven as we are, join us. You’ll be working in a dynamic and supportive environment, with some of the brightest and the friendliest people in the sector, and you’ll be helping shape an industry.

The Role

We are seeking a Research Tech IV-(XTAL) to join a dynamic and growing team at the Walter Reed Army Institute of Research (WRAIR) Wound Infection Department (WID). WID is tasked with delivering specific, effective countermeasures for infection of combat wounds pre-injury, at the point-of-injury, and post-injury. The Structural Biology (XTAL) group focuses on drug discovery and development using structure-based drug design against microbial pathogens of military relevance. Researchers in this group express, purify, and crystallize ESKAPEE pathogen proteins of interest and utilize sophisticated techniques such as circular dichroism, isothermal calorimetry, molecular modeling, and x-ray crystallography to study small molecule drug-protein interactions.

What You Will Be Doing:

• Providing technical support in several research areas, including: Molecular biology, Microbiology, Enzymology, Protein Expression and Purification, X-ray Crystallography, and Structure-function Relationships.
• Performing microbiological and biochemical studies on various bacterial pathogens of military relevance under biosafety level 2 and 3 conditions.
• Culturing infectious agents for use in laboratory procedures. Preparing pure sterile DNA samples from microbial agents in biosafety level 2 and 3 laboratories. Contributing to the development of research protocols and grant proposals, and in the conduct of research related to therapeutic discovery and development for trauma-related infections.
• Following established protocols to perform microbiological, MIC, molecular biological, and enzyme assays, as well as protein expression, purification, and crystallization.
• Organizing and tabulating results of studies and preparing data summaries.
• Maintaining accurate and appropriate research records, including a laboratory notebook compliant with standards of replicability and WRAIR/Army regulations.
• Ensuring a safe workplace by being aware of and observing appropriate safety and occupational health rules and regulations. Attending safety training relative to the position and reporting any safety infractions to the facility Safety Officer.
• Completing all required safety, biosafety, and security training classes.
• Obtaining required annual occupational physical examinations and serologic tests, as well as any required security clearances for work in department biosafety level 2 and 3 laboratories.
• Completing specialized training in new methods and procedures as needed, including in the use of data analysis software.

Your Profile:

• Citizenship: Must be a US citizen.
• Clearance: Ability to obtain NACI.
• Education: BS or M.S. in an appropriate discipline (e.g., microbiology, biochemistry, molecular biology, biophysics).
• Years’ Experience: Minimum of 7 years' related laboratory experience. Must have experience in BSL-2 environments and the ability to conduct safe work in this laboratory environment.

• Interpersonal Skills: Strong communication, problem-solving, teamwork, attention to detail, reliability, and multitasking abilities.

Additional Information:

Location: Walter Reed Army Institute of Research (WRAIR), 503 Robert Grant Avenue, Silver Spring, MD 20910

Benefits of Working in ICON:Our success depends on the quality of our people. That’s why we’ve made it a priority to build a culture that rewards high performance and nurtures talent.We offer very competitive salary packages. And to keep them competitive, we regularly benchmark them against our competitors. Our annual bonuses reflect delivery of performance goals – both ours and yours.We also provide a range of health-related benefits to employees and their families and offer competitive retirement plans – and related benefits such as life assurance – so you can save and plan with confidence for the years ahead.But beyond the competitive salaries and comprehensive benefits, you’ll benefit from an environment where you are encouraged to fulfil your sense of purpose and drive lasting change.ICON is an equal opportunity and inclusive employer and is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know through the form below.

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