Heart at Work Study
6 de abril de 2021 actualizado por: Tyler Quinn, University of Pittsburgh
Cardiovascular Mechanisms of the Occupational Physical Activity Health Paradox: 24-hour Physical Activity, Blood Pressure, and Heart Rate
This is an observational study to examine the cardiovascular mechanisms of increased cardiovascular mortality in those with high activity occupations.
Descripción general del estudio
Estado
Terminado
Descripción detallada
The current proposal uses a repeated-measures, within-subject design to address our aims.
Twenty male participants will report to the laboratory to provide informed consent, complete baseline assessments, and receive ambulatory monitors.
Following this session, each participant will wear physical activity and ambulatory cardiovascular monitors for 7 days, including at least one non-work day and one work day.
Characterization of work activity will use physical activity data from self-reported time at work (Specific Aim I).
The 24-hour cardiovascular load (HR and BP) and nocturnal HRV will be compared across work and non-work days (Specific Aim II).
Lastly, whether fitness level or job strain modify the difference in cardiovascular strain between work vs. non-work days will be evaluated (Specific Aim III).
Tipo de estudio
De observación
Inscripción (Actual)
19
Contactos y Ubicaciones
Esta sección proporciona los datos de contacto de quienes realizan el estudio e información sobre dónde se lleva a cabo este estudio.
Ubicaciones de estudio
-
-
Pennsylvania
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Pittsburgh, Pennsylvania, Estados Unidos, 15261
- Physical Activity and Weight Management Research Laboratory
-
-
Criterios de participación
Los investigadores buscan personas que se ajusten a una determinada descripción, denominada criterio de elegibilidad. Algunos ejemplos de estos criterios son el estado de salud general de una persona o tratamientos previos.
Criterio de elegibilidad
Edades elegibles para estudiar
35 años a 59 años (Adulto)
Acepta Voluntarios Saludables
No
Géneros elegibles para el estudio
Masculino
Método de muestreo
Muestra no probabilística
Población de estudio
Middle-aged male food service workers
Descripción
Inclusion Criteria:
- middle age (35-59 years)
- male
- self-report working full-time in the food service industry (≥30 hours/week)
- self-report predominantly completing light intensity activity job responsibilities (≥75% work time walking, light movement, or standing)
Exclusion Criteria:
- Resting blood pressure of ≥150 mmHg systolic and/or ≥95 mmHg diastolic
- currently taking medications that are known to affect blood pressure or heart rate (e.g. Beta-blockers, ACE inhibitors, etc.)
- greater than low risk to participate in physical activity as determined by PAR-Q (answer of yes to any of the 7 physical activity readiness questionnaire questions)
- report working a second job in addition to their primary full-time job
- report working overnight shifts (10pm-6am)
- reported physical dysfunction (inability to walk 2 city blocks or climb 2 flights of stairs)
- inability to complete the sub-maximal exercise test to completion (80% age-predicted heart rate maximum)
- Currently being treated for a serious medical condition such as kidney disease, liver disease, cancer, or heart disease.
Plan de estudios
Esta sección proporciona detalles del plan de estudio, incluido cómo está diseñado el estudio y qué mide el estudio.
¿Cómo está diseñado el estudio?
Detalles de diseño
- Modelos observacionales: Caso cruzado
- Perspectivas temporales: Transversal
¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
|
24-hour Heart Rate
Periodo de tiempo: 24 hours
|
We will calculate the average heart rate over each 24 hour period throughout a one week monitoring period.
|
24 hours
|
Medidas de resultado secundarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
|
24-hour Ambulatory Systolic Blood Pressure
Periodo de tiempo: 24 hours
|
We will calculate the average systolic blood pressure over a 24-hour period on two separate days (workdays versus non-workdays).
|
24 hours
|
|
Nocturnal Heart Rate Variability, RMSSD
Periodo de tiempo: approximately 8 hours (sleep time)
|
We will calculate the average heart rate variability during each night's sleep for a total of one week.
The specific HRV variable presented is root mean square successive differences (RMSSD).
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approximately 8 hours (sleep time)
|
|
Physical Activity Pattern. Steps Per Day
Periodo de tiempo: 1 week
|
This physical activity metric of steps per day was calculated as average number of steps during each day type (work versus non-workdays) throughout one week
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1 week
|
|
Nocturnal Heart Rate Variability, SDNN
Periodo de tiempo: approximately 8 hours (sleep time)
|
We will calculate the average heart rate variability during each night's sleep for a total of one week.
The specific HRV variable presented is standard deviation of the normal to normal RR intervals (SDNN).
|
approximately 8 hours (sleep time)
|
|
Nocturnal Heart Rate Variability, LF
Periodo de tiempo: approximately 8 hours (sleep time)
|
We will calculate the average heart rate variability during each night's sleep for a total of one week.
The specific HRV variable presented is low frequency power (LF).
|
approximately 8 hours (sleep time)
|
|
Nocturnal Heart Rate Variability, HF
Periodo de tiempo: approximately 8 hours (sleep time)
|
We will calculate the average heart rate variability during each night's sleep for a total of one week.
The specific HRV variable presented is high frequency power (HF).
|
approximately 8 hours (sleep time)
|
|
Physical Activity Pattern. MVPA
Periodo de tiempo: 1 week
|
This physical activity metric of minutes of moderate to vigorous physical activity was calculated as average minutes during each day type (work versus non-workdays) throughout one week
|
1 week
|
|
Physical Activity Pattern. LPA
Periodo de tiempo: 1 week
|
This physical activity metric of minutes of light physical activity was calculated as average minutes during each day type (work versus non-workdays) throughout one week
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1 week
|
|
Physical Activity Pattern. Sedentary
Periodo de tiempo: 1 week
|
This physical activity metric of minutes of sedentary time was calculated as average minutes during each day type (work versus non-workdays) throughout one week
|
1 week
|
|
Physical Activity Pattern. Upright
Periodo de tiempo: 1 week
|
This physical activity metric of minutes of upright time was calculated as average minutes during each day type (work versus non-workdays) throughout one week
|
1 week
|
|
24-hour Ambulatory Diastolic Blood Pressure
Periodo de tiempo: 24 hours
|
We will calculate the average diastolic blood pressure over a 24-hour period on two separate days (workdays versus non-workdays).
|
24 hours
|
Colaboradores e Investigadores
Aquí es donde encontrará personas y organizaciones involucradas en este estudio.
Patrocinador
Investigadores
- Investigador principal: Tyler D Quinn, MS, graduate student
Fechas de registro del estudio
Estas fechas rastrean el progreso del registro del estudio y los envíos de resultados resumidos a ClinicalTrials.gov. Los registros del estudio y los resultados informados son revisados por la Biblioteca Nacional de Medicina (NLM) para asegurarse de que cumplan con los estándares de control de calidad específicos antes de publicarlos en el sitio web público.
Fechas importantes del estudio
Inicio del estudio (Actual)
17 de octubre de 2019
Finalización primaria (Actual)
20 de abril de 2020
Finalización del estudio (Actual)
24 de julio de 2020
Fechas de registro del estudio
Enviado por primera vez
28 de agosto de 2019
Primero enviado que cumplió con los criterios de control de calidad
29 de agosto de 2019
Publicado por primera vez (Actual)
30 de agosto de 2019
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
3 de mayo de 2021
Última actualización enviada que cumplió con los criterios de control de calidad
6 de abril de 2021
Última verificación
1 de abril de 2021
Más información
Términos relacionados con este estudio
Términos MeSH relevantes adicionales
Otros números de identificación del estudio
- STUDY19050097
Plan de datos de participantes individuales (IPD)
¿Planea compartir datos de participantes individuales (IPD)?
No
Descripción del plan IPD
Upon completion of all data collection, data will be analyzed and summary conclusions will be published in a peer reviewed scientific journal.
Información sobre medicamentos y dispositivos, documentos del estudio
Estudia un producto farmacéutico regulado por la FDA de EE. UU.
No
Estudia un producto de dispositivo regulado por la FDA de EE. UU.
No
producto fabricado y exportado desde los EE. UU.
No
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