The Association Between Blood Eosinophilsp in Thai COPD Patients: A Prospective Study

The Association Between Blood Eosinophils and Clinical Outcomes of Chronic Obstructive Pulmonary Disease Patients: A Prospective Study

Patrocinadores

Patrocinador principal: Prince of Songkla University

Fuente Prince of Songkla University
Resumen breve

The association of blood eosinophil as a biomarker for eosinophilic Thai COPD patients, such as COPD exacerbation, hospital admission, lung functions and mortlity.

Descripción detallada

The prospective one year study in Thai COPD patients for the clinical outcomes of COPD compare between eosinophilic and non-eosinophilic which determine by blood eosinophil counts equal or more than 300 cells/microliters. The primary outcomes was COPD exacerbation, the secondary outcomes were lung function, dyspnea and quality of life.

Estado general Completed
Fecha de inicio December 1, 2017
Fecha de Terminación December 31, 2018
Fecha de finalización primaria December 31, 2018
Tipo de estudio Observational
Resultado primario
Medida Periodo de tiempo
Acute worsening of respiratory symptoms 1 year
Resultado secundario
Medida Periodo de tiempo
Physiological outcomes 1 year
health related quality of life 1 year
Inscripción 145
Condición
Intervención

Tipo de intervención: Other

Nombre de intervención: observatory

Descripción: observation for 1 year period

Otro nombre: clinical outcomes

Elegibilidad

Método de muestreo: Non-Probability Sample

Criterios:

Inclusion Criteria:

- diagnosis of COPD by GOLD criteria

Exclusion Criteria:

1. high blood eosinophil from known causes such as systemic corticosteroid use, malignancy, parasitic infection

2. Patients who had previous acute exacerbation within 30-day before study entry

3. Patients who had previous systemic corticosteroids used within 30-day before study entry

Género: All

Edad mínima: 40 Years

Edad máxima: 80 Years

Voluntarios Saludables: No

Oficial general
Apellido Papel Afiliación
Kanung Saejiam, MS Study Director Prince of Songkla University
Ubicación
Instalaciones: Faculty of Medicine, Prince of Songkla university
Ubicacion Paises

Thailand

Fecha de verificación

October 2019

Fiesta responsable

Tipo: Principal Investigator

Afiliación del investigador: Prince of Songkla University

Nombre completo del investigador: Siwasak Juthong

Título del investigador: Faculty of Medicine

Tiene acceso ampliado No
Grupo de brazo

Etiqueta: eosinophilic COPD patient

Descripción: COPD patient with blood eosinophil equal or > 300 cells/µL

Etiqueta: non-eosinophilic COPD patient

Descripción: COPD patient with blood eosinophil < 300 cells/µL

Datos del paciente Undecided
Información de diseño del estudio

Modelo de observación: Cohort

Perspectiva de tiempo: Prospective

Fuente: ClinicalTrials.gov