Apical Periodontitis and Glycemic Control in Diabetic and Non-diabetic Egyptian Sub-population
Prevalence of Apical Periodontitis and it's Association With Glycemic Control in Diabetic and Non-diabetic Egyptian Sub-population: A Cross-sectional Study
This observational cross-sectional study aims to assess the prevalence of apical periodontitis in diabetic and non-diabetic adult Egyptian patients and to evaluate its association with glycemic control measured by glycated hemoglobin (HbA1c). Participants will undergo clinical examination, digital panoramic radiographic assessment, and HbA1c measurement.
Descripción general del estudio
Estado
Condiciones
Descripción detallada
Apical periodontitis is an inflammatory disease of the periapical tissues that develops as a consequence of endodontic infection. Diabetes mellitus has been associated with an increased prevalence of apical periodontitis, although the available evidence remains limited and inconsistent. In addition, the relationship between glycemic control and apical periodontitis remains unclear, and population-specific data in Egypt are limited.
This observational cross-sectional study will assess the prevalence of apical periodontitis in diabetic and non-diabetic adult Egyptian patients and evaluate the association between glycemic control and apical periodontitis. Participants will be recruited from outpatient dental clinics of the Endocrine and Diabetes Center in Cairo, Egypt, in collaboration with the Department of Endodontics, Faculty of Dentistry, Cairo university.
Eligible participants will be Egyptian males and females aged 21 years or older with at least eight teeth present. Participants will undergo standardized clinical oral examination, digital panoramic radiographic examination, and measurement of glycated hemoglobin (HbA1c). Apical periodontitis will be assessed radiographically based on the presence or absence of periapical radiolucency. Participants will be classified into diabetic and non-diabetic groups according to HbA1c levels.
The primary objective is to assess the prevalence of apical periodontitis in diabetic and non-diabetic patients. The secondary objective is to evaluate the association between HbA1c levels and the presence of apical periodontitis. The planned sample size is 88 participants, with 44 participants in each group.
Tipo de estudio
Inscripción (Estimado)
Contactos y Ubicaciones
Estudio Contacto
- Nombre: Yara Yousif Kairi
- Número de teléfono: +201555003176
- Correo electrónico: Yara.kairi@dentistry.cu.edu.eg
Criterios de participación
Criterio de elegibilidad
Edades elegibles para estudiar
Acepta Voluntarios Saludables
Géneros elegibles para el estudio
Método de muestreo
Población de estudio
Adult Egyptian male and female patients aged 21 years or older with at least 8 teeth, recruited from outpatient dental clinics at the Faculty of Dentistry, Cairo University and the Endocrine and Diabetes Center, Cairo, Egypt. Participants will be classified into diabetic and non-diabetic groups based on their measured HbA1c levels.
Descripción
Inclusion Criteria:
- Adult Egyptian males and females
- 21 years or older
- At least 8 teeth present
- Willing to undergo clinical and radiographic examination, HbA1c measurement, -Willing to provide informed consent.
Exclusion Criteria:
- Participants younger than 21 years
- fewer than 8 teeth
- Those who refuse clinical or radiographic examination
- Patients with systemic diseases other than diabetes that may affect oral or periapical health.
Plan de estudios
¿Cómo está diseñado el estudio?
Detalles de diseño
- Modelos observacionales: OTHER
- Perspectivas temporales: CROSS_SECTIONAL
Cohortes e Intervenciones
Grupo / Cohorte |
|---|
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Group 1: diabetic participants
Participants with HbA1c ≥6.5% |
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Group 2: non-diabetic participants
Participants with HbA1c <6.5%. |
¿Qué mide el estudio?
Medidas de resultado primarias
Medida de resultado |
Medida Descripción |
Periodo de tiempo |
|---|---|---|
|
Prevalence of apical periodontitis
Periodo de tiempo: During the 6-month study/recruitment period.
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Presence or absence of apical periodontitis assessed by digital panoramic radiographic examination using binary scoring based on the presence of periapical radiolucency. |
During the 6-month study/recruitment period.
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Colaboradores e Investigadores
Patrocinador
Fechas de registro del estudio
Fechas importantes del estudio
Inicio del estudio (Estimado)
Finalización primaria (Estimado)
Finalización del estudio (Estimado)
Fechas de registro del estudio
Enviado por primera vez
Primero enviado que cumplió con los criterios de control de calidad
Publicado por primera vez (Actual)
Actualizaciones de registros de estudio
Última actualización publicada (Actual)
Última actualización enviada que cumplió con los criterios de control de calidad
Última verificación
Más información
Términos relacionados con este estudio
Términos MeSH relevantes adicionales
Otros números de identificación del estudio
- 24.9.2024
Plan de datos de participantes individuales (IPD)
¿Planea compartir datos de participantes individuales (IPD)?
Descripción del plan IPD
Individual participant data will not be shared with individual researchers outside the study team. Study data will be accessible to the Principal Investigator and supervisors and will be protected to maintain participant confidentiality.
Información sobre medicamentos y dispositivos, documentos del estudio
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Estudia un producto de dispositivo regulado por la FDA de EE. UU.
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