Application of the Single Use Negative Pressure Wound Therapy Device (PICO) on a Heterogeneous Group of Surgical and Traumatic Wounds

Caroline Payne, Daren Edwards, Caroline Payne, Daren Edwards

Abstract

Objectives: Traumatic wounds and surgery inherently have their complications. Localized infections, wound dehiscence, and excessive wound leakage can be devastating to the patient with a prolonged recovery, but it is also costly to the hospital with an increased length of stay, extra workload, and dressing changes. The single use PICO (Smith and Nephew Healthcare, Hull, United Kingdom) negative pressure wound therapy (NPWT) dressing has revolutionized our management of various acute, chronic, and high output wounds. It requires fewer dressing changes than conventional practice, is used in the outpatient setting, and is a necessary adjuvant therapy to hasten wound healing.

Aims: To observe the efficacy of the PICO vacuum-assisted healing within a cost improvement programme.

Settings: Plastic surgery department, Royal London Hospital.

Materials and methods: Twenty-one patients with a diversity of postoperative or posttraumatic wounds were considered suitable for PICO application and treated totally on an outpatient basis once the PICO dressing was applied. All wounds were then subjected to continued PICO dressings until healed.

Results: All patients tolerated the PICO well with no dressing failure or failure to comply. The number of dressings per patient ranged from 1 to 7. The cost per patient of treatment ranged from £120 to £1578. Estimated cost of all PICO dressing for 21 patients including plastic surgery dressing clinic appointments = £13,345. Median length of treatment to healing (days) = 16; standard deviation = 9.5. Eight patients would have had an inpatient bed stay with conventional therapy, total 24 bed days saved at Bartshealth @£325 per day.

Conclusions: The outpatient application of a disposable NPWT can benefit a wide range of clinical wounds that optimizes patient care, promotes rapid wound healing, and importantly helps manage costs.

Keywords: early patient discharge; negative pressure wound dressing; plastic surgery; single use device; wound management.

Figures

Figure 1
Figure 1
(a) Wound on first presentation in surgical outpatients department. Excessive amount of exudate from radiation damaged skin breakdown and fat necrosis. Bleeding from the nipple area as eschar debrided. (b) First application of the PICO with Allevyn foam to cover the nipple area. Dressing pad shows exudate leaking into the dressing after the first application. (c) Area after 7 PICO applications, June 2012.
Figure 2
Figure 2
(a) Wound prior to pectoralis major flap cover. (b) Postoperative stage following flap repair and skin graft coverage. Wound shows first stages of breakdown along proximal edges on July 14, 2012. (c) First application of PICO on July 18, 2012. Extra OpSite around the dressing edges to facilitate neck movement. PICO changed twice weekly for 2 weeks to monitor exudate management and observe wound coverage. (d) Wound on August 16, 2012. Decision made to discontinue PICO and manage conservatively and treat areas of over granulation with nitrate.
Figure 3
Figure 3
(a) Wound at initial debridement. (b) At the time of first SSG check and reapplication of PICO. (c) Healed fully by October 2012.
Figure 4
Figure 4
(a) Central wound dehiscence left flank. PICO applied on 13 July. (b) Wound nearly closed by August 7. No further PICO dressing from this time and fully healed by end August.
Figure 5
Figure 5
(a) Initial view of the left groin showing the site of SLNB and the difficulties in covering the wound area with adequate dressings. The dehiscence was not a concern but the copious amount of seroma leakage. (b) Dressing 1 week later with exudate manageable. PICO dressing had been changed at 3 days by general practitioner, then returning to PDC at RLH for weekly review. (c) SLNB site 5 weeks later. Seroma fluid now dissipated, small exit wound. Decision made to stop PICO and return to conventional dressings. Wound healed 2 weeks later.

References

    1. National institute for Health and Care Excellence Prevention and control of healthcare associated infections PH36. Available at: . Accessed July 8, 2013.
    1. National institute for Health and Care Excellence Surgical site infection: prevention and treatment of surgical site infection. Available at: . Accessed July 8, 2013.
    1. Morykwas MJ, Argenta LC, Shelton-Brown EI, et al. Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg. 1997;38:553–62.
    1. Argenta LC, Morykwas MJ. Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Ann Plast Surg. 1997;38:563–76. discussion 577.
    1. Malmsjo M, Gustafsson L, Lindstedt S, et al. The effects of variable, intermittent, and continuous negative pressure wound therapy, using foam or gauze, on wound contraction, granulation tissue formation, and ingrowth into the wound filler. Eplasty. 2012;12:e5.
    1. Weed T, Ratliff C, Brake D. Quantifying bacterial bioburden during negative pressure wound therapy. Br J Plast Surg. 2001;54:238–42.
    1. Banwell P, Withey S, Holten I. The use of negative pressure to promote healing. Br J Plast Surg. 1998;51:79.
    1. Payne CE, Williams A, Hart N. Lotus petal flaps for scrotal reconstruction combined with Integra™ resurfacing of the penis and anterior abdominal wall following necrotizing fasciitis. JPRAS. 2009;62:393–7.
    1. Avery CM, Pereira J, Moody A, Whitworth I. Clinical experience with the negative pressure wound dressing. Br J Oral Maxillofac Surg. 2000;38(4):343–5.
    1. Blackburn JH, II, Boemi L, Hall WW, et al. Negative-pressure dressings as a bolster for skin grafts. Ann Plast Surg. 1998;40:453–7.
    1. Hynes PJ, Earley MJ, Lawlor D. Split-thickness skin grafts and negative-pressure dressings in the treatment of axillary hidradenitis suppurativa. Br J Plast Surg. 2002;55(6):507–9.
    1. Jeffery SLA. Advanced wound therapies in the management of severe military lower limb trauma: a new perspective. Eplasty. 2009;9:e28.
    1. Bollero D, Carnino R, Risso D, Gangemi EN, Stell M. Acute complex traumas of the lower limbs: a modern reconstructive approach with negative pressure therapy. Wound Repair Regen. 2007;15(4):589–94.
    1. Tauber R, Schmid S, Horn T, et al. Inguinal lymph node dissection: epidermal vacuum therapy for prevention of wound complications. J Plast Reconstr Aesthet Surg. 2013;66(3):390–6.
    1. Wilmore DW, Kehlet H, Sawyer F. Management of patients in fast track surgery. BMJ. 2001;322(7284):473–6.
    1. Kanakaris NK, Thanasas C, Keramaris N, Kontakis G, Granick M, Giannoudis P. The efficacy of negative pressure wound therapy in the management of lower extremity trauma: review of clinical evidence. Injury. 2007;38(suppl 5):S9–S18.
    1. Timmons J. The use of the Versatile-1 wound vacuum system to treat a patient with a challenging grade 3 pressure ulcer in continuing care. Wounds. 2006;2:125.
    1. Chariker M, Jeter K, Tintle T, Bottsford J. Effective management of incisional and cutaneous fistulae with closed suction wound drainage. Contemp Surg. 1989;34:59–63.
    1. Cro C, George KJ, Donnely J, et al. Vacuum-assisted closure system in the management of enterocutaneous fistulae. Postgrad Med J. 2002;78:364–5.
    1. de Weerd L, Kjæve J, Aghajani E, Elvenes OP. The sandwich design: a new method to close a high-output enterocutaneous fistula and an associated abdominal wall defect. Ann Plast Surg. 2007;58(5):580–3.
    1. Llanos S, Danilla S, Barraza C, et al. Effectiveness of negative pressure closure in the integration of split-thickness skin grafts: a randomized, double-masked, controlled trial. Ann Surg. 2006;244(5):700–5.
    1. Bickels J, Kollender Y, Wittig J, Cohen N, Meller I, Malawer M. Vacuum-assisted wound closure after resection of musculoskeletal tumors. Clin Orthop Relat Res. 2005;441:346–50.
    1. Greenwood JE, Mackie IP. Neck contracture release with matriderm collagen/elastin dermal matrix. Eplasty. 2011;11:e16.
    1. Baldwin C, Potter M, Clayton E, Irvine L, Dye J. Topical negative pressure stimulates endothelial migration and proliferation: a suggested mechanism for improved integration of Integra. Ann Plast Surg. 2009;62(1):92–6.
    1. Jeschke MG, Rose C, Angele P, et al. Development of new reconstructive techniques: use of Integra in combination with fibrin glue and negative-pressure therapy for reconstruction of acute and chronic wounds. Plast Reconstr Surg. 2004;113:525–30.
    1. Leffler M, Horch RE, Dragu A, Bach AD. The use of the artificial dermis (Integra) in combination with vacuum assisted closure for reconstruction of an extensive burn scar: a case report. J Plast Reconstr Aesthet Surg. 2010;63(1):e32–5.
    1. Malmsjö M, Ingemansson R, Martin R, Huddleston E. Negative pressure wound therapy using gauze or polyurethane open cell foam: similar early effects on pressure transduction and tissue contraction in an experimental porcine wound model. Wound Repair Regen. 2009;17:200–5.
    1. Sposato G, Molea G, Di Caprio G, Scioli M, LaRusca I, Ziccardi R. Ambulant vacuum-assisted closure of skin-graft dressing in the lower limbs using a portable mini-VAC device. Br J Plast Surg. 2001;54(3):235–7.
    1. Argenta LC, Morykwas MJ, Marks MW, et al. Vacuum-assisted closure: state of clinic art. Plast Reconstr Surg. 2006;117:127S–42S.
    1. Armstrong DG, Marston WA, Reyzelmen A, Kirsner RS. Comparative effectiveness of mechanically and electrically powered negative pressure wound therapy devices: a multicenter randomized controlled trial. Wound Rep. Reg. 2012;20(3):332–41.
    1. Birke-Sorenson H, Malmsjo M, Rome P, et al. Evidence-based recommendations for negative pressure wound therapy: treatment variables (pressure levels, wound filler, and contact layer): step towards an international consensus. J Plast and Reconstr Aesthet Surg. 2011;64(suppl):S1–S16.
    1. Runkel N, Krug, Berg E, et al. Evidence-based recommendations for the use of negative pressure wound therapy in traumatic wounds and reconstructive surgery: steps towards an international consensus. Injury. 2011;42:S1–12.
    1. Glass GE, Nanchahal J. The methodology of negative pressure wound therapy: separating fact from fiction. J Plast Reconstr Aesthet Surg. 2012;65:989–1001.
    1. Morykwas MJ, Faler BJ, Pearce DJ, et al. Effects of varying levels of subatmospheric pressure on the rate of granulation tissue formation in experimental wounds in swine. Ann Plast Surg. 2001;47:547–51.
    1. Kairinos N, Solomons M, Hudson DA. Negative-pressure wound therapy I: the paradox of negative-pressure wound therapy. Plast Reconstr Surg. 2009;123:589–98. discussion 599-600.
    1. Kairinos N, Voogd AM, Botha PH, et al. Negative-pressure wound therapy II: negative-pressure wound therapy and increased perfusion. Just an illusion? Plast Reconstr Surg. 2009;123:601–12.
    1. Morykwas MJ, Faler BJ, Pearce DJ, Argenta LC. Effects of varying levels of subatmospheric pressure on the rate of granulation tissue formation in experimental wounds in swine. Ann Plast Surg. 2001;47(5):547–51.
    1. Kasai Y, Nemoto H, Kimura N, Ito Y, Sumiya N. Application of low-pressure negative pressure wound therapy to ischaemic wounds. J Plast Reconstr Aesthet Surg. 2012;65:395–8.
    1. Venturi M, Attinger C, Mesbahi A, Hess C, Graw K. Mechanisms and clinical applications of the vacuum-assisted closure (VAC) device: a review. Am J Clin Dermatol. 2005;6(3):185–94.
    1. Pikaitis C, Molnar J. Subatmospheric pressure wound therapy and the vacuum-assisted closure device: basic science and current clinical successes. Exp Rev Med Dev. 2006;3(2):175–84.
    1. Dunn RM, Ignotz R, Mole T, Cockwill J, Smith J. Assessment of gauze-based negative pressure wound therapy in the split-thickness skin graft clinical pathway: an observational study. Eplasty. 2011;11:e14.
    1. Rozen MW, Shahbaz S, Morsi A. An improved alternative to vacuum-assisted closure (VAC) as a negative pressure dressing in lower limb split skin grafting: a clinical trial. J Plast Reconstr Aesthet Surg. 2008;61:334–7.
    1. Tonouchi H, Ohmori Y, Kobayashi M, et al. Operative morbidity associated with groin dissections. Surg Today. 2004;34:413–8.
    1. Chuo CB. Management of groin seromas with open drainage with external quilting sutures and open drainage. J Plast and Reconstr Aesthet Surg. 2010;63:e551–2.
    1. Pu LLQ, Jahania MS, Mentzer RM. Successful management of recalcitrant groin lymphorrhoea with the combination of intraoperative lymphatic mapping and muscle flap. J Plast Reconstr Aesthet Surg. 2006;59:1363–6.
    1. Tauber R, Schmid S, Horn T, et al. Inguinal lymph node dissection: epidermal vacuum therapy for prevention of wound complications. J Plast Reconstr Aesthet Surg. 2013;66(3):390–6.
    1. Stannard JP, Atkins BZ, O’Malley D, et al. Use of negative pressure therapy on closed surgical incisions: a case series. Ostomy Wound Manage. 2009;55:58–66.
    1. Stannard JP, Gabriel A, Lehner B. Use of negative pressure wound therapy over clean, closed surgical incisions. Int Wound J. 2012;9(suppl 1):32–9.
    1. Calderon WL, Llanos S, Leniz P, Danilla S, Vielma R, Calderon D. Double negative pressure for seroma treatment in trochanteric area. Ann Plast Surg. 2009;63(6):659–60.
    1. Labanaris AP, Polykandriotis E, Horch RE. The effect of vacuum-assisted closure on lymph vessels in chronic wounds. J Plast Reconstr Aesthet Surg. 2009;62:1068–75.
    1. Ilczyszyn A, Ridha H, Durrani AJ. Management of chyle leak post neck dissection: A case report and literature review. J Plast Reconstr Aesthet Surg. 2011;64:223–30.
    1. de Gier HH, Balm AJ, Bruning PF, Gregor RT, Hilgers FJ. Systematic approach to the treatment of chylous leakage after neck dissection. Head Neck. 1996;18(4):347–51.
    1. Evans D, Land L. Topical negative pressure for treating chronic wounds: a systematic review. Br J of Plast Surg. 2001;54:238–42.

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