Prevalence of diabetes mellitus and impaired glucose regulation in Spain: the Di@bet.es Study
F Soriguer, A Goday, A Bosch-Comas, E Bordiú, A Calle-Pascual, R Carmena, R Casamitjana, L Castaño, C Castell, M Catalá, E Delgado, J Franch, S Gaztambide, J Girbés, R Gomis, G Gutiérrez, A López-Alba, M T Martínez-Larrad, E Menéndez, I Mora-Peces, E Ortega, G Pascual-Manich, G Rojo-Martínez, M Serrano-Rios, S Valdés, J A Vázquez, J Vendrell, F Soriguer, A Goday, A Bosch-Comas, E Bordiú, A Calle-Pascual, R Carmena, R Casamitjana, L Castaño, C Castell, M Catalá, E Delgado, J Franch, S Gaztambide, J Girbés, R Gomis, G Gutiérrez, A López-Alba, M T Martínez-Larrad, E Menéndez, I Mora-Peces, E Ortega, G Pascual-Manich, G Rojo-Martínez, M Serrano-Rios, S Valdés, J A Vázquez, J Vendrell
Abstract
Aims/hypothesis: The Di@bet.es Study is the first national study in Spain to examine the prevalence of diabetes and impaired glucose regulation.
Methods: A population-based, cross-sectional, cluster sampling study was carried out, with target population being the entire Spanish population. Five thousand and seventy-two participants in 100 clusters (health centres or the equivalent in each region) were randomly selected with a probability proportional to population size. Participation rate was 55.8%. Study variables were a clinical and demographic structured survey, lifestyle survey, physical examination (weight, height, BMI, waist and hip circumference, blood pressure) and OGTT (75 g).
Results: Almost 30% of the study population had some carbohydrate disturbance. The overall prevalence of diabetes mellitus adjusted for age and sex was 13.8% (95% CI 12.8, 14.7%), of which about half had unknown diabetes: 6.0% (95% CI 5.4, 6.7%). The age- and sex-adjusted prevalence rates of isolated impaired fasting glucose (IFG), isolated impaired glucose tolerance (IGT) and combined IFG-IGT were 3.4% (95% CI 2.9, 4.0%), 9.2% (95% CI 8.2, 10.2%) and 2.2% (95% CI 1.7, 2.7%), respectively. The prevalence of diabetes and impaired glucose regulation increased significantly with age (p < 0.0001), and was higher in men than in women (p < 0.001).
Conclusions/interpretation: The Di@bet.es Study shows, for the first time, the prevalence rates of diabetes and impaired glucose regulation in a representative sample of the Spanish population.
References
- Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract. 2010;87:4–14. doi: 10.1016/j.diabres.2009.10.007.
- Gardete-Correia L, Boavida JM, Raposo JF, et al. First diabetes prevalence study in Portugal: PREVADIAB study. Diabet Med. 2011;27:879–881. doi: 10.1111/j.1464-5491.2010.03017.x.
- Valdes S, Rojo-Martinez G, Soriguer F. Evolution of prevalence of type 2 diabetes in adult Spanish population. Med Clin (Barc) 2007;129:352–355. doi: 10.1157/13109554.
- Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med. 1998;15:539–553. doi: 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>;2-S.
- DECODE-Study-Group Age- and sex-specific prevalences of diabetes and impaired glucose regulation in 13 European cohorts. Diabetes Care. 2003;26:61–69. doi: 10.2337/diacare.26.1.61.
- Varo JJ, Martinez-Gonzalez MA, de Irala-Estevez J, Kearney J, Gibney M, Martinez JA. Distribution and determinants of sedentary lifestyles in the European Union. Int J Epidemiol. 2003;32:138–146. doi: 10.1093/ije/dyg116.
- Saely CH, Aczel S, Koch L, et al. Diabetes as a coronary artery disease risk equivalent: before a change of paradigm? Eur J Cardiovasc Prev Rehabil. 2010;17:94–99. doi: 10.1097/HJR.0b013e32833100f0.
- Guize L, Jaffiol C, Gueniot M, et al. Diabetes and socio-economic deprivation. A study in a large French population. Bull Acad Natl Med. 2008;192:1707–1723.
Source: PubMed