Blood component therapy: Which, when and how much

Rajesh Chand Arya, Gs Wander, Pankaj Gupta, Rajesh Chand Arya, Gs Wander, Pankaj Gupta

Abstract

Blood transfusion refers to the perioperative administration of blood and blood components. Adherence to proper indications for blood component therapy is essential because of its potential adverse effects and costs of transfusion. Over the years, the significance of blood components in treating certain diseases or conditions has been recognized. In this article, the most commonly used blood components along with the new developments in component therapy have been discussed. Recommendations by different academic and clinical trials and studies have been presented for quick reference. The individual coagulation factors are discussed in brief.

Keywords: Blood transfusion; bleeding disorder; blood components; coagulopathy.

Conflict of interest statement

Conflict of Interest: None declared.

References

    1. Practice Guidelines for Perioperative Blood Transfusion and Adjuvant Therapies: An Updated Report by the American Society of Anesthesiologists Task Force on Perioperative Blood Transfusion and Adjuvant Therapies. Anesthesiology. 2006;105:198–208.
    1. Stehling L, Luban NL, Anderson KC, Sayers MH, Long A, Attar S, et al. Guidelines for blood utilization review. Transfusion. 1994;34:438–48.
    1. Despotis GJ, Grishaber JE, Goodnough LT. The effect of an intraoperative treatment algorithm on physicians′ transfusion practice in cardiac surgery. Transfusion. 1994;34:290–6.
    1. Paone G, Spencer T, Silverman NA. Blood conservation in coronary artery surgery. Surgery. 1994;116:672–8.
    1. Wallace EL, Surgenor DM, Hao HS, An J, Chapman RH, Churchill WH. Collection and transfusion of blood and blood components in the United States, 1989. Transfusion. 1993;33:139–44.
    1. Standl T. Haemoglobin-based erythrocyte transfusion substitutes. Expert Opin Biol Ther. 2001;1:831–43.
    1. Water JA, Trouwborst A, Spense RK. A pilot study of the effects of perflubron emulsion, AF0104, on mixed venous oxygen tension in anesthetized surgical patients. Anesth Analg. 1996;82:103–7.
    1. Consensus conference. Platelet transfusion therapy. JAMA. 1987;257:1777–80.
    1. Bode AP. Preclinical testing of lyophilized platelets as a product for transfusion medicine. Transfus Sci. 1995;16:183–5.
    1. Bode AP, Read MS. Lyophilized platelets: Continued development. Transfus Sci. 2000;22:99–105.
    1. Chao FC, Kim BK, Houranieh AM, Liang FH, Konrad MW, Swisher SN, et al. Infusible platelet membrane microvesicles: A potential transfusion substitute for platelets. Transfusion. 1996;36:536–42.
    1. Hehne HJ, Nyman HB, Burri M, Wolfe G. Management of bleeding disorders in traumatic-haemorrhagic shock states with deep frozen fresh plasma. Eur J Intensive Care Med. 1979;2:157–61.
    1. College of American Pathologists: Practice parameter for the use of fresh-frozen plasma, cryoprecipitate, and platelets. JAMA. 1994;271:777–81.
    1. Swenson MR. Autoimmunity and immunotherapy. J IV Nuts. 2000;23:SB–13.

Source: PubMed

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