Trigger point dry needling for the treatment of myofascial pain syndrome: current perspectives within a pain neuroscience paradigm

César Fernández-de-Las-Peñas, Jo Nijs, César Fernández-de-Las-Peñas, Jo Nijs

Abstract

Myofascial pain syndrome is a pain condition characterized by the presence of trigger points. Current evidence, mostly experimental studies, clearly supports a role of trigger points on peripheral and central sensitization since they are able to contribute to sensitization of peripheral nociceptors, spinal dorsal horn neurons, and the brainstem. Several interventions are proposed for treating trigger points, dry needling being one of the most commonly used by clinicians. There is no consensus on the clinical application of trigger point dry needling: some authors propose that local twitch responses should be elicited during the needling intervention to be effective, whereas others do not. The application of trigger point dry needling is able to reduce the excitability of the central nervous system by reducing peripheral nociception associated to the trigger point, by reducing dorsal horn neuron activity, and by modulating pain-related brainstem areas. However, the effects are mainly observed in the short-term, and effect sizes are moderateto small. Therefore, the current review proposes that the application of trigger point dry needling should be integrated into current pain neuroscience paradigm by combining its application with pain neuroscience education, graded exercise and manual therapy. Additionally, patient's expectations, beliefs, previous experiences and patient-clinician interaction should be considered when integrating trigger point dry needling into a comprehensive treatment approach.

Keywords: chronic pain; dry needling; sensitization; trigger point.

Conflict of interest statement

Dr Jo Nijs has co-authored a book for clinicians on pain neuroscience education, but the royalties for the book were collected by the Vrijie Universiteit Brussel and not him personally. Dr. Fernandez-de-las-Penas is an instructor in Trigger Point Therapy and also receive royalties from published books. The authors report no other conflicts of interest in this work.

Figures

Figure 1
Figure 1
Proposed model explaining potential variables influencing neurophysiological mechanisms of trigger point dry needling.

References

    1. Handwerker H, Arendt-Nielsen L. Pain Model: Translational Relevance and Applications. Seattle: IASP Press; 2013.
    1. Simons DG, Travell JG, Simons L. Myofascial Pain and Dysfunction. The Trigger Point Manual. 3th ed. Philadelphia: Wolters Kluwer; 2019.
    1. Fernández-de-Las-Peñas C, Dommerholt J. International consensus on diagnostic criteria and clinical considerations of myofascial trigger points: a Delphi study. Pain Med. 2018;19:142–150. doi:10.1093/pm/pnx207
    1. Palacios-Ceña M, Castaldo M, Wang K, et al. Relationship of active trigger points with related disability and anxiety in people with tension-type headache. Medicine. 2017;96:e6548. doi:10.1097/MD.0000000000006548
    1. Ferracini GN, Florencio LL, Dach F, et al. Myofascial trigger points and migraine-related disability in women with episodic and chronic migraine. Clin J Pain. 2017;33:109–115. doi:10.1097/AJP.0000000000000387
    1. Fernández-de-Las-Peñas C, Galán-del-Río F, Alonso-Blanco C, Jiménez-García R, Arendt-Nielsen L, Svensson P. Referred pain from muscle trigger points in the masticatory and neck-shoulder musculature in women with temporomandibular disorders. J Pain. 2010;11:1295–1304. doi:10.1016/j.jpain.2010.03.005
    1. Cerezo-Téllez E, Torres-Lacomba M, Mayoral-Del Moral O, Sánchez-Sánchez B, Dommerholt J, Gutiérrez-Ortega C. Prevalence of myofascial pain syndrome in chronic non -specific neck pain: a population-based cross-sectional descriptive study. Pain Med. 2016;17:2369–2377. doi:10.1093/pm/pnw114
    1. Fernández-Pérez A, Villaverde-Gutiérrez C, Mora-Sánchez A, Alonso-Blanco C, Sterling M, Fernández-de-Las-Peñas C. Muscle trigger points, pressure pain threshold, and cervical range of motion in patients with high level of disability related to acute whiplash injury. J Orthop Sports Phys Ther. 2012;42:634–641. doi:10.2519/jospt.2012.4117
    1. Bron C, Dommerholt J, Stegenga B, Wensing M, Oostendorp RA. High prevalence of shoulder girdle muscles with myofascial trigger points in patients with shoulder pain. BMC Musculoskelet Disord. 2011;12:139. doi:10.1186/1471-2474-12-181
    1. Fernández-Carnero J, Fernández-de-Las-Peñas C, de la Llave-Rincón AI, Ge HY, Arendt-Nielsen L. Prevalence of and referred pain from myofascial trigger points in the forearm muscles in patients with lateral epicondylalgia. Clin J Pain. 2007;23(4):353–360. doi:10.1097/AJP.0b013e31803b3785
    1. Iglesias-González JJ, Muñoz-García MT, Rodrigues-de-Souza DP, Alburquerque-Sendín F, Fernández-de-Las-Peñas C. Myofascial trigger points, pain, disability, and sleep quality in patients with chronic nonspecific low back pain. Pain Med. 2013;14:1964–1970. doi:10.1111/pme.12224
    1. Chiarotto A, Clijsen R, Fernandez-de-Las-Peñas C, Barbero M. Prevalence of myofascial trigger points in spinal disorders: a systematic review and meta-analysis. Arch Phys Med Rehabil. 2016;97:316–337. doi:10.1016/j.apmr.2015.09.021
    1. Shah JP, Phillips TM, Danoff JV, Gerber LH. An in vivo microanalytical technique for measuring the local biochemical milieu of human skeletal muscle. J Appl Physiol. 2005;99:1977–1984. doi:10.1152/japplphysiol.00419.2005
    1. Shah JP, Danoff J, Desai M, et al. Biochemicals associated with pain and inflammation are elevated in sites near to and remote from active myofascial trigger points. Arch Phys Med Rehabil. 2008;89:16–23. doi:10.1016/j.apmr.2007.10.018
    1. Shah JP, Gilliams EA. Uncovering the biochemical milieu of myofascial trigger points in vivo microdialysis: an application of muscle pain concepts to myofascial pain syndrome. J Bodyw Mov Ther. 2008;12:371–384. doi:10.1016/j.jbmt.2008.06.006
    1. Li LT, Ge HY, Yue S, Arendt-Nielsen L. Nociceptive and non-nociceptive hypersensitivity at latent myofascial trigger points. Clin J Pain. 2009;25:132–137. doi:10.1097/AJP.0b013e3181878f87
    1. Wang YH, Ding X, Zhang Y et al. Ischemic compression block attenuates mechanical hyperalgesia evoked from latent myofascial trigger point. Exp Brain Res. 2010;202:265–267. doi:10.1007/s00221-009-2129-2
    1. Kuan TS, Hong CZ, Chen JT, Chen SM, Chien CH. The spinal cord connections of the myofascial trigger spots. Eur J Pain. 2007;11:624–634. doi:10.1016/j.ejpain.2006.10.001
    1. Xie P, Qin B, Song G, et al. Microstructural abnormalities were found in brain gray matter from patients with chronic myofascial pain. Front Neuroanat. 2016;10:122. doi:10.3389/fnana.2016.00122
    1. Lucas KR, Rich PA, Polus BI. Muscle activation patterns in the scapular positioning muscles during loaded scapular plane elevation: the effects of latent myofascial trigger points. Clin Biomech. 2010;25:765–770. doi:10.1016/j.clinbiomech.2010.05.006
    1. Ge HY, Arendt-Nielsen L, Madeleine P. Accelerated muscle fatigability of latent myofascial trigger points in humans. Pain Med. 2012;13:957–964. doi:10.1111/j.1526-4637.2012.01416.x
    1. Ibarra JM, Ge HY, Wang C, Martínez Vizcaíno V, Graven-Nielsen T, Arendt-Nielsen L. Latent myofascial trigger points are associated with an increased antagonistic muscle activity during agonist muscle contraction. J Pain. 2011;12:1282–1288. doi:10.1016/j.jpain.2011.09.005
    1. Annaswamy TM, De Luigi AJ, O‘Neill BJ, et al. Emerging concepts in the treatment of myofascial pain: a review of medications, modalities, and needle-based interventions. Pm R. 2011;3:940–961. doi:10.1016/j.pmrj.2011.06.013
    1. Dommerholt J, Fernandez-de-Las-Peñas C. Trigger Point Dry Needling: An Evidence and Clinical- Based Approach. 2th ed. London: Churchill Livingstone, Elsevier; 2019.
    1. American Physical Therapy Association (APTA). Description of Dry Needling in Clinical Practice: An Educational Resource Paper. Virginia: APTA Public Policy P, and Professional Affairs Unit; 2013.
    1. Autralian Society of Acupuncture Physiotherapists (ASAP). Guidelines for Safe Acupuncture and Dry Needling Practice. Wellington: Autralian Society of Acupuncture Physiotherapists (ASAP); 2014.
    1. Hong C. Lidocaine injection versus dry needling to myofascial trigger point. The importance of the local twitch response. Am J Phys Med Rehabil. 1994;73:256–263.
    1. Fernández-Carnero J, Gilarranz-de-Frutos L, Leon-Hernandez JV, et al. Effectiveness of different deep dry needling dosages in the treatment of patients with cervical myofascial pain: a pilot RCT. Am J Phys Med Rehabil. 2017;96:726–733. doi:10.1097/PHM.0000000000000733
    1. Koppenhaver SL, Walker MJ, Rettig C, et al. The association between dry needling-induced twitch response and change in pain and muscle function in patients with low back pain: a quasi-experimental study. Physiotherapy. 2017;103:131–137. doi:10.1016/j.physio.2016.05.002
    1. Perreault T, Dunning J, Butts R. The local twitch response during trigger point dry needling: is it necessary for successful outcomes?. J Bodyw Mov Ther. 2017;21:940–947. doi:10.1016/j.jbmt.2017.03.008
    1. Poveda-Pagán EJ, Lozano-Quijada C, Segura-Heras JV, Peral-Berna M, Lumbreras B. Referred pain patterns of the infraspinatus muscle elicited by deep dry needling and manual palpation. J Altern Complement Med. 2017;23:890–896. doi:10.1089/acm.2016.0306
    1. McEvoy J, Dommerholt J, Rice D, Holmes L, Grobli C, Fernández-de-Las-Penas C. Guidelines for Safe Dry Needling Practice for Chartered Physiotherapists. Dublin: Irish Society of Chartered Physiotherapist (ISCP); 2011.
    1. Halle JS, Halle RJ. Pertinent dry needling considerations for minimizing adverse effects: part one. Int J Sports Phys Ther. 2016;11:651–662.
    1. Halle JS, Halle RJ. Pertinent dry needling considerations for minimizing adverse effects: part two. Int J Sports Phys Ther. 2016;11:810–819.
    1. McCulloch M, Nachat A, Schwartz J, Casella-Gordon V, Cook J. Acupuncture safety in patients receiving antcoagulants: a systematic review. Perm J. 2015;19:68–73. doi:10.7812/TPP/14-057
    1. Brady S, McEvoy J, Dommerholt J, Doody C. Adverse events following trigger point dry needling: a prospective survey of chartered physiotherapist. J Man Manip Ther. 2014;22:134–140. doi:10.1179/2042618613Y.0000000044
    1. Hampton DA, Kaneko RT, Simeon E, Moren A, Rowell S, Watters JM. Acupuncture related pneumothorax. Med Acupunct. 2014;26:241–245. doi:10.1089/acu.2013.1022
    1. Lee SW, Ahn JY, Choi WJ, et al. A needle penetrating the stomach cavity after acupuncture. Clin Endosc. 2014;47:258–261. doi:10.5946/ce.2014.47.3.258
    1. Chun KJ, Lee SG, Son BS. Kim Do H Life-threatening cardiac tamponade: a rare complication of acupuncture. J Cardiothorac Surg. 2014;9:61. doi:10.1186/1749-8090-9-61
    1. Lee JH, Lee H, Jo DJ. An acute cervical epidural hematoma as a complication of dry needling. Spine. 2011;36:E891–E893. doi:10.1097/BRS.0b013e3181fc1e38
    1. Ji GY, Oh CH, Choi WS, Lee JB. Three cases of hemiplegia after cervical paraspinal muscle needling. Spine J. 2015;15:9–13. doi:10.1016/j.spinee.2014.11.007
    1. Kim DC, Glenzer S, Johnson A, Nimityongskul P. Deep infection following dry needling in a young athlete: an underreported complication of an increasingly prevalent modality: A case report. J Bone Joint Surg. 2018;8:e73. doi:10.2106/JBJS.CC.18.00097
    1. American Physical Therapy Association (APTA). Physical Therapists and the Performance of Dry Needling: An Educational Resource Paper. Virginia: APTA Public Policy P, and Professional Affairs Unit; 2012.
    1. Martín-Pintado-Zugasti A, Mayoral Del Moral O, Rd G, Fernández-Carnero J. Post-needling soreness after myofascial trigger point dry needling: current status and future research. J Bodyw Mov Ther. 2018;22:941–946. doi:10.1016/j.jbmt.2018.01.003
    1. Domingo A, Mayoral O, Monterde S, Santafe MM. Neuromuscular damage and repair after dry needling in mice. Evid Based Complement Alternat Med. 2013;2013:260806. doi:10.1155/2013/260806
    1. Baraja-Vegas L, Martín-Rodríguez S, Piqueras-Sanchiz F, et al. Localization of muscle edema and changes on muscle contractility after dry needling of latent trigger points in the gastrocnemius muscle. Pain Med. 2019. doi:10.1093/pm/pny306
    1. Martin-Pintado Zugasti A, Fernández-Carnero J, León-Hernández JV, et al. Postneedling soreness and tenderness after different dosages of dry needling of an active myofascial trigger point in patients with neck pain: a randomised controlled trial. Pm R. 2018;1934–1482(18):30287–30289.
    1. Martin-Pintado Zugasti A, Rodriguez-Fernandez AL, Garcia-Muro F, et al. Effects of spray and stretch on postneedling soreness and sensitivity after dry needling of a latent myofascial trigger point. Arch Phys Med Rehabil. 2014;95:1925–1932. doi:10.1016/j.apmr.2014.05.021
    1. Martin-Pintado-Zugasti A, Pecos-Martin D, Rodriguez-Fernandez AL, et al. Ischemic compression after dry needling of a latent myofascial trigger point reduces post-needling soreness intensity and duration. Pm R. 2015;7:1026–1034. doi:10.1016/j.pmrj.2015.03.021
    1. Salom-Moreno J, Jimenez-Gomez L, Gomez-Ahufinger V, et al. Effects of low-load exercise on postneedling-induced pain after dry needling of active trigger point in individuals with subacromial pain syndrome. PMR. 2017;9:1208–1216. doi:10.1016/j.pmrj.2017.04.012
    1. Lewit K. The needle effect in the relief of myofascial pain. Pain. 1979;6:83–90.
    1. Ong J, Claydon LS. The effect of dry needling for myofascial trigger points in the neck and shoulders: a systematic review and meta-analysis. J Bodyw Mov Ther. 2014;18:390–398. doi:10.1016/j.jbmt.2013.11.009
    1. Liu L, Huang QM, Liu QG, et al. Effectiveness of dry needling for myofascial trigger points associated with neck and shoulder pain: a systematic review and meta-analysis. Arch Phys Med Rehabil. 2015;96:944–955. doi:10.1016/j.apmr.2014.12.015
    1. Canadian Agency for Drugs and Technologies in Health. Dry Needling and Injection for Musculoskeletal and Joint Disorders: A Review of the Clinical Effectiveness, Cost-Effectiveness, and Guidelines. Ottawa: Canadian Agency for Drugs and Technologies in Health; 2016.
    1. Kietrys DM, Palombaro KM, Azzaretto E, et al. Effectiveness of dry needling for upper-quarter myofascial pain: a systematic review and meta-analysis. J Orthop Sports Phys Ther. 2013;43:620–634. doi:10.2519/jospt.2013.4668
    1. Morihisa R, Eskew J, McNamara A, Young J. Dry needling in subjects with muscular trigger points in the lower quarter: A systematic review. Int J Sports Phys Ther. 2016;11:1–14.
    1. Braithwaite FA, Walters JL, Li LSK, Moseley GL, Williams MT, McEvoy MP. Effectiveness and adequacy of blinding in the moderation of pain outcomes: systematic review and meta-analyses of dry needling trials. PeerJ. 2018;6:e5318. doi:10.7717/peerj.5318
    1. Vier C, Almeida MB, Neves ML, Santos ARSD, Bracht MA. The effectiveness of dry needling for patients with orofacial pain associated with temporomandibular dysfunction: a systematic review and meta-analysis. Braz J Phys Ther. 2019;23:3-11.
    1. France S, Bown J, Nowosilskyj M, Mott M, Rand S, Walters J. Evidence for the use of dry needling and physiotherapy in the management of cervicogenic or tension-type headache: a systematic review. Cephalalgia. 2014;34:994–1003. doi:10.1177/0333102414523847
    1. Hall ML, Mackie AC, Ribeiro DC. Effects of dry needling trigger point therapy in the shoulder region on patients with upper extremity pain and dysfunction: a systematic review with meta-analysis. Physiotherapy. 2018;104:167–177. doi:10.1016/j.physio.2017.08.001
    1. Hu HT, Gao H, Ma RJ, Zhao XF, Tian HF, Li L. Is dry needling effective for low back pain?: A systematic review and PRISMA-compliant meta-analysis. Medicine. 2018;97:e11225. doi:10.1097/MD.0000000000011225
    1. He C, Ma H. Effectiveness of trigger point dry needling for plantar heel pain: a meta-analysis of seven randomized controlled trials. J Pain Res. 2017;10:1933–1942. doi:10.2147/JPR.S141607
    1. Gattie E, Cleland JA, Snodgrass S. The effectiveness of trigger point dry needling for musculoskeletal conditions by physical therapists: A systematic review and meta-analysis. J Orthop Sports Phys Ther. 2017;47:133–149. doi:10.2519/jospt.2017.7096
    1. Arias-Buría JL, Fernández-de-Las-Peñas C, Palacios-Ceña M, Koppenhaver SL, Salom-Moreno J. Exercises and dry needling for subacromial pain syndrome: A randomized parallel-group trial. J Pain. 2017;18:11–18. doi:10.1016/j.jpain.2016.08.013
    1. Arias-Buría JL, Martín-Saborido C, Cleland J, Koppenhaver SL, Plaza-Manzano G, Fernández-de-Las-Peñas C. Cost-effectiveness evaluation of the inclusion of dry needling into an exercise program for subacromial pain syndrome: evidence from a randomized clinical trial. Pain Med. 2018;19:2336–2347. doi:10.1093/pm/pny021
    1. Espí-López GV, Serra-Añó P, Vicent-Ferrando J, et al. Effectiveness of inclusion of dry needling in a multimodal therapy program for patellofemoral pain: A randomized parallel-group trial. J Orthop Sports Phys Ther. 2017;47:392–440. doi:10.2519/jospt.2017.7389
    1. Sánchez-Romero EA, Pecos-Martín D, Calvo-Lobo C, Ochoa-Sáez V, Burgos-Caballero V, Fernández-Carnero J. Effects of dry needling in an exercise program for older adults with knee osteoarthritis: A pilot clinical trial. Medicine. 2018;97:e11255. doi:10.1097/MD.0000000000011255
    1. Dunning J, Butts R, Young I, et al. Periosteal electrical dry needling as an adjunct to exercise and manual therapy for knee osteoarthritis: a multicenter randomized clinical trial. Clin J Pain. 2018;34:1149–1158. doi:10.1097/AJP.0000000000000634
    1. Cagnie B, Dewitte V, Barbe T, Timmermans F, Delrue N, Meeus M. Physiologic effects of dry needling. Curr Pain Headache Rep. 2013;17:348. doi:10.1007/s11916-013-0348-5
    1. Gerwin RD, Dommerholt J, Shah JP. An expansion of Simons‘ integrated hypothesis of trigger point formation. Curr Pain Headache Rep. 2004;8:468–475.
    1. Chou LW, Hsieh YL, Kao MJ, Hong JZ. Remote influences of acupuncture on the pain intensity and the amplitude changes of endplate noise in the myofascial trigger point of the upper trapezius muscle. Arch Phys Med Rehabil. 2009;90:905–912. doi:10.1016/j.apmr.2008.12.020
    1. Liu QG, Liu L, Huang QM, Nguyen TT, Ma YT, Zhao JM. Decreased spontaneous electrical activity and acetylcholine at myofascial trigger spots after dry needling treatment: A pilot study. Evid Based Complement Alternat Med. 2017;2017:3938191. doi:10.1155/2017/3938191
    1. Abbaszadeh-Amirdehi M, Ansari NN, Naghdi S, Olyaei G, Nourbakhsh MR. Therapeutic effects of dry needling in patients with upper trapezius myofascial trigger points. Acupunct Med. 2017;35:85–92. doi:10.1136/acupmed-2016-011082
    1. Abbaszadeh-Amirdehi ANN, Naghdi S. Nourbakhsh. Neurophysiological and clinical effects of dry needling in patients with upper trapezius myofascial trigger points. MR. J Bodyw Mov Ther. 2017;21:48–52. doi:10.1016/j.jbmt.2016.04.014
    1. Cagnie B, Barbe T, De Ridder E, Van Oosterwijck J, Cools A, Danneels L. The influence of dry needling of the trapezius muscle on muscle blood flow and oxygenation. J Manipulative Physiol Ther. 2012;35:685–691. doi:10.1016/j.jmpt.2012.10.005
    1. Dommerholt J. Dry needling: peripheral and central considerations. J Manual Manipul Ther. 2011;19:223–237. doi:10.1179/106698111X13129729552065
    1. Butts R, Dunning J, Perreault T, Mourad F, Grubb M. Peripheral and spinal mechanisms of pain and dry needling mediated analgesia: A clinical resource guide for health care professionals. Int J Phys Med Rehabil. 2016;4:2. doi:10.4172/2329-9096.1000327
    1. Chou LW, Kao MJ, Lin JG. Probable mechanisms of needling therapies for myofascial pain control. Evid Based Complement Alternat Med. 2012;2012:705327. doi:10.1155/2012/705327
    1. Hsieh YL, Yang SA, Yang CC, Chou LW. Dry needling at myofascial trigger spots of rabbit skeletal muscles modulates the biochemicals associated with pain, inflammation, and hypoxia. Evid Based Complement Alternat Med. 2012;2012:342165. doi:10.1155/2012/342165
    1. Hsieh YL, Kao MJ, Kuan TS, Chen SM, Chen JT, Hong CZ. Dry needling to a key myofascial trigger point may reduce the irritability of satellite MTrPs. Am J Phys Med Rehabil. 2007;86:397–403. doi:10.1097/PHM.0b013e31804a554d
    1. Tsai CT, Hsieh LF, Kuan TS, Kao MJ, Chou LW, Hong CZ. Remote effects of dry needling on the irritability of the myofascial trigger point in the upper trapezius muscle. Am J Phys Med Rehabil. 2010;89:133–140. doi:10.1097/PHM.0b013e3181a5b1bc
    1. Hsieh YL, Chou LW, Joe YS, Hong CZ. Spinal cord mechanism involving the remote effects of dry needling on the irritability of myofascial trigger spots in rabbit skeletal muscle. Arch Phys Med Rehabil. 2011;92:1098–1105. doi:10.1016/j.apmr.2010.11.018
    1. Hsieh YL, Yang SA, Liu SY, Chou LW, Honc CZ. Remote dose-dependent effects of dry needling at distant myofascial trigger spots of rabbit skeletal muscles on reduction of substance P levels of proximal muscle and spinal cords. Biomed Res Int. 2014;2014:982121. doi:10.1155/2014/982121
    1. Srbely JZ, Dickey JP, Lee D, Lowerison M. Dry needle stimulation of myofascial trigger points evokes segmental anti-nociceptive effects. J Rehabil Med. 2010;42:463–468. doi:10.2340/16501977-0535
    1. Audette JF, Wang F, Smith H. Bilateral activation of motor unit potentials with unilateral needle stimulation of active myofascial trigger points. Am J Phys Med Rehabil. 2004;83:368–374.
    1. Chae Y, Chang DS, Lee SH, et al. Inserting needles into the body: a meta-analysis of brain activity associated with acupuncture needle stimulation. J Pain. 2013;14:215–222. doi:10.1016/j.jpain.2012.11.011
    1. Niddam DM, Chan RC, Lee SH, Yeh TC, Hsieh JC. Central modulation of pain evoked from myofascial trigger point. Clin J Pain. 2007;23:440–448. doi:10.1097/AJP.0b013e318058accb
    1. Louw A, Zimney K, Puentedura EJ, Diener I. The efficacy of pain neuroscience education on musculoskeletal pain: a systematic review of the literature. Physiother Theory Pract. 2016;32:332–355. doi:10.1080/09593985.2016.1194646
    1. Geneen LJ, Moore RA, Clarke C, Martin D, Colvin LA, Smith BH. Physical activity and exercise for chronic pain in adults: an overview of cochrane reviews. Cochrane Database Syst Rev. 2017;4:CD011279.
    1. Brunner E, De Herdt A, Minguet P, Baldew SS, Probst M. Can cognitive behavioural therapy-based strategies be integrated into physiotherapy for the prevention of chronic low back pain? A systematic review. Dis Rehabil. 2013;35:1–10. doi:10.3109/09638288.2012.683848
    1. Williams AC, Eccleston C, Morley S. Psychological therapies for the management of chronic pain (excluding headache) in adults. Cochrane Database Syst Rev. 2012;11:CD007407.
    1. Nijs J, Mairesse O, Neu D, et al. Sleep disturbances in chronic pain: neurobiology, assessment and treatment in physical therapist practice. Phys Ther. 2018;98:325–335. doi:10.1093/ptj/pzy020
    1. Lluch Girbes E, Meeus M, Baert I, Balancing NJ. “hands-on” with “hands-off” physical therapy interventions for the treatment of central sensitization pain in osteoarthritis. Man Ther. 2015;20:349–352. doi:10.1016/j.math.2014.07.017
    1. Woolf CJ. Central sensitization: implications for the diagnosis and treatment of pain. Pain. 2011;152:S2–15. doi:10.1016/j.pain.2010.09.030
    1. Kosek E, Cohen M, Baron R, et al. Do we need a third mechanistic descriptor for chronic pain states? Pain. 2016;157:1382–1386. doi:10.1097/j.pain.0000000000000507
    1. Fernández-de-Las-Peñas C, Dommerholt J. Myofascial trigger points: peripheral or central phenomenon? Curr Rheumatol Rep. 2014;16:395. doi:10.1007/s11926-013-0395-2
    1. Malfliet A, Kregel J, Coppieters I, et al. Effect of pain neuroscience education combined with cognition-targeted motor control training on chronic spinal pain: A randomized clinical trial. JAMA Neurol. 2018;75:808–817. doi:10.1001/jamaneurol.2018.0492
    1. Fernández-de-Las Peñas C, Ortega-Santiago R, de la Llave-Rincón AI, et al. Manual physical therapy versus surgery for carpal tunnel syndrome: A randomized parallel-group trial. J Pain. 2015;16:1087–1094. doi:10.1016/j.jpain.2015.07.012
    1. Legrain V, Iannetti GD, Plaghki L, Mouraux A. The pain matrix reloaded: a salience detection system for the body. Prog Neurobiol. 2011;93:111–124. doi:10.1016/j.pneurobio.2010.10.005
    1. Bjorkedal E, Flaten MA. Expectations of increased and decreased pain explains the effect of conditioned pain modulation in females. J Pain Res. 2012;5:289–300. doi:10.2147/JPR.S33559
    1. Louw A, Nijs J, Puentedura EJ. A clinical perspective on a pain neuroscience education approach to manual therapy. J Man Manip Ther. 2017;25:160–168. doi:10.1080/10669817.2017.1323699
    1. Téllez-García M, de-la- Llave-Rincón AI, Salom-Moreno J, Palacios-Ceña M, Ortega-Santiago R, Fernández-de-Las-Peñas C. Neuroscience education in addition to trigger point dry needling for the management of patients with mechanical chronic low back pain: a preliminary clinical trial. J Bodyw Mov Ther. 2015;19:464–472. doi:10.1016/j.jbmt.2014.11.012
    1. Wager TD, Rilling JK, Smith E, et al. Placebo-induced changes in FMRI in the anticipation and experience of pain. Science. 2004;303:11621167. doi:10.1126/science.1093065
    1. Moseley GL, Arntz A. The context of a noxious stimulus affects the pain it evokes. Pain. 2007;133:64–71. doi:10.1016/j.pain.2007.03.002
    1. Legrain V, Crombez G, Verhoeven K, Mouraux A. The role of working memory in the attentional control of pain. Pain. 2011;152:453–459. doi:10.1016/j.pain.2010.11.024
    1. Longo MR, Iannetti GD, Mancini F, Driver J, Haggard P. Linking pain and the body: neural correlates of visually induced analgesia. J Neurosci. 2012;32:2601–2607. doi:10.1523/JNEUROSCI.4031-11.2012

Source: PubMed

3
Suscribir