Bucindolol Decreases Atrial Fibrillation Burden in Patients With Heart Failure and the ADRB1 Arg389Arg Genotype
Jonathan P Piccini, Christopher Dufton, Ian A Carroll, Jeff S Healey, William T Abraham, Yaariv Khaykin, Ryan Aleong, Steven K Krueger, William H Sauer, Stephen B Wilton, Michiel Rienstra, Dirk J van Veldhuisen, Inder S Anand, Michel White, A John Camm, Paul D Ziegler, Debra Marshall, Michael R Bristow, Stuart J Connolly, Genotype-Directed Comparative Effectiveness Trial of Bucindolol and Toprol-XL for Prevention of Atrial Fibrillation/Atrial Flutter in Patients with Heart Failure Trial Investigators*, F Ayala-Paredes, A Bakbak, M L Bernier, D H Birnie, B Coutu, E Crystal, M W Deyell, K M Dyrda, M C Hartleib, Z W Laksman, P Leong-Sit, C A Morillo, A S Pandey, F Philippon, S Vizel, P Andréka, Z Csanadi, G Z Duray, T Forster, G Kerkovits, B Merkely, A C Nagy, T Simor, D Czarnecka, J D Kasprzak, W J Musial, G Raczak, J Szachniewicz, J K Wranicz, S Apostolović, S Hinić, V Miloradović, D Simić, G J Milhous, A Oomen, T J Romer, L M van Vijk, P B Adamson, J D Allred, N Amjadi, M M Bahu, A J Bank, A E Berman, M A Bernabei, R S Bhagwat, L Borgatta, A J Buda, R T Cole, J L Collier, S J Compton, O Costantini, M R Costanzo, I M Dauber, M P Donahue, I Dor, G F Egnacyzk, E J Eichhorn, C C Eiswirth, S Emani, G A Ewald, R C Forde-McLean, M D Gelernt, D E Haines, C A Henrikson, J M Herre, B Herweg, L Ilkhanoff, L R Jackson 2nd, A Lala, R Lo, B London, B D Lowes, J A Mackall, V Malhotra, F A McGrew, S Murali, A Natale, K R Nilsson, J Okolo, M V Perez, R S Phang, R Ranjan, M Y Rashtian, M J Ross, S M Samii, T Shinn, M B Shoemaker, S A Strickberger, V N Tholakanahalli, A Tzur, P J Wang, L T Younis, Jonathan P Piccini, Christopher Dufton, Ian A Carroll, Jeff S Healey, William T Abraham, Yaariv Khaykin, Ryan Aleong, Steven K Krueger, William H Sauer, Stephen B Wilton, Michiel Rienstra, Dirk J van Veldhuisen, Inder S Anand, Michel White, A John Camm, Paul D Ziegler, Debra Marshall, Michael R Bristow, Stuart J Connolly, Genotype-Directed Comparative Effectiveness Trial of Bucindolol and Toprol-XL for Prevention of Atrial Fibrillation/Atrial Flutter in Patients with Heart Failure Trial Investigators*, F Ayala-Paredes, A Bakbak, M L Bernier, D H Birnie, B Coutu, E Crystal, M W Deyell, K M Dyrda, M C Hartleib, Z W Laksman, P Leong-Sit, C A Morillo, A S Pandey, F Philippon, S Vizel, P Andréka, Z Csanadi, G Z Duray, T Forster, G Kerkovits, B Merkely, A C Nagy, T Simor, D Czarnecka, J D Kasprzak, W J Musial, G Raczak, J Szachniewicz, J K Wranicz, S Apostolović, S Hinić, V Miloradović, D Simić, G J Milhous, A Oomen, T J Romer, L M van Vijk, P B Adamson, J D Allred, N Amjadi, M M Bahu, A J Bank, A E Berman, M A Bernabei, R S Bhagwat, L Borgatta, A J Buda, R T Cole, J L Collier, S J Compton, O Costantini, M R Costanzo, I M Dauber, M P Donahue, I Dor, G F Egnacyzk, E J Eichhorn, C C Eiswirth, S Emani, G A Ewald, R C Forde-McLean, M D Gelernt, D E Haines, C A Henrikson, J M Herre, B Herweg, L Ilkhanoff, L R Jackson 2nd, A Lala, R Lo, B London, B D Lowes, J A Mackall, V Malhotra, F A McGrew, S Murali, A Natale, K R Nilsson, J Okolo, M V Perez, R S Phang, R Ranjan, M Y Rashtian, M J Ross, S M Samii, T Shinn, M B Shoemaker, S A Strickberger, V N Tholakanahalli, A Tzur, P J Wang, L T Younis
Abstract
[Figure: see text].
Trial registration: ClinicalTrials.gov NCT01970501.
Keywords: atrial fibrillation; atrial flutter; bucindolol; heart failure; metoprolol.
Source: PubMed