Current and Upcoming Therapies for Ocular Surface Chemical Injuries
Alireza Baradaran-Rafii, Medi Eslani, Zeeshan Haq, Ebrahim Shirzadeh, Michael J Huvard, Ali R Djalilian, Alireza Baradaran-Rafii, Medi Eslani, Zeeshan Haq, Ebrahim Shirzadeh, Michael J Huvard, Ali R Djalilian
Abstract
Chemical injuries frequently result in vision loss, disfigurement, and challenging ocular surface complications. Acute interventions are directed at decreasing the extent of the injury, suppressing inflammation, and promoting ocular surface re-epithelialization. Chronically, management involves controlling inflammation along with rehabilitation and reconstruction of the ocular surface. Future therapies aimed at inhibiting neovascularization and promoting ocular surface regeneration should provide more effective treatment options for the management of ocular chemical injuries.
Keywords: chemical burn; cornea; limbal stem cell deficiency; ocular chemical burn; ocular surface; stem cell.
Conflict of interest statement
The authors have no commercial or proprietary interest in any concept or product discussed in this article.
Copyright © 2016 Elsevier Inc. All rights reserved.
Figures
Source: PubMed