Anthroposophic medicine: an integrative medical system originating in europe

Gunver S Kienle, Hans-Ulrich Albonico, Erik Baars, Harald J Hamre, Peter Zimmermann, Helmut Kiene, Gunver S Kienle, Hans-Ulrich Albonico, Erik Baars, Harald J Hamre, Peter Zimmermann, Helmut Kiene

Abstract

Anthroposophic medicine is an integrative multimodal treatment system based on a holistic understanding of man and nature and of disease and treatment. It builds on a concept of four levels of formative forces and on the model of a three-fold human constitution. Anthroposophic medicine is integrated with conventional medicine in large hospitals and medical practices. It applies medicines derived from plants, minerals, and animals; art therapy, eurythmy therapy, and rhythmical massage; counseling; psychotherapy; and specific nursing techniques such as external embrocation. Anthroposophic healthcare is provided by medical doctors, therapists, and nurses. A Health-Technology Assessment Report and its recent update identified 265 clinical studies on the efficacy and effectiveness of anthroposophic medicine. The outcomes were described as predominantly positive. These studies as well as a variety of specific safety studies found no major risk but good tolerability. Economic analyses found a favorable cost structure. Patients report high satisfaction with anthroposophic healthcare.

Keywords: Anthroposophic medicine; holistic; integrative; patient-centered.

Figures

Figure 1
Figure 1
Filderklinik, an anthroposophic hospital in Filderstadt, Germany. Source: Filderklinik; reprinted with permission.
Figure 2
Figure 2
Anthroposophic physician performing surgery at an anthroposophic hospital. Source: Gemeinschaftskrankenhaus Havelhöhe; reprinted with permission.
Figure 3
Figure 3
Nursing packs. Source: Jürg Buess, Hiscia; reprinted with permission.
Figure 4
Figure 4
Eurythmy therapy. Source: Professional Association for Eurythmy Therapy; reprinted with permission.

References

    1. Kienle G: Anthroposophische Medizin. Seidler E, editor Wörterbuch medizinischer Grundbegriffe Freiburg, Basel, Wien, Germany: Herder Verlag; 1979: 33–9
    1. Lindenberg C. Rudolf Steiner—a biography Great Barrington, MA: SteinerBooks; 2012
    1. Steiner R. Goethe's theory of knowledge: an outline of the epistemology of his worldview (1886) Great Barrington, MA: SteinerBooks; 2008
    1. Steiner R. Goethe's conception of the world (1897) London: The Anthroposophical Publishing Company; 1928
    1. Steiner R. The story of my life London: The Anthroposophical Publishing Company; 1928
    1. Steiner R. An outline of esoteric science (1910) Great Barrington, MA: Anthroposophic Press; 1997
    1. Steiner R. The riddles of philosophy (1900/1901) Great Barrington, MA: SteinerBooks; 2009
    1. Steiner R. Truth and knowledge (1892) Great Barrington, MA: Steiner Books; 1981
    1. Kant I. Critique of pure reason (1781) Mineola, NY: Dover Publications; 2003
    1. du Bois-Reymond E. Jugendbriefe an Eduard Hallmann Berlin: Reimer Verlag; 1918
    1. von Helmholtz H. Über die Erhaltung der Kraft Leipzig, Germany: Engelmann Ver-lag; 1915
    1. Virchow R. Über das Bedürfnis und die Richtigkeit einer Medizin vom mechanischen Standpunkt. Arch Path Anat. 1907;7:188
    1. Kienle GS, Kiene H, Albonico HU. Anthroposophic medicine: effectiveness, utility, costs, safety Stuttgart, NY: Schattauer Verlag; 2006
    1. Vogel L. Der dreigliedrige Mensch Dornach: Verlag am Goetheanum; 2005
    1. Steiner R. Wesensglieder und Dreigliederung. In:Anthroposophische Leitsätze (32-34). Dornach 1925. Der Merkurstab. 2007;(4):381
    1. Kienle GS, Kiene H. “Beyond reductionism”—zur Notwendigkeit komplexer, organ-ismischer Ansätze in der Tumorimmunologie und Onkologie; Kienle GS, Kiene H, Die Mistel in der Onkologie. Stuttgart, NY: Schattauer Verlag; 2003: 333–432
    1. Kienle G, Kiene H. From reductionism to holism: systems-oriented approaches in cancer research. Global Adv Health Med. 2012;1(5):68–77
    1. Rosslenbroich B. Outline of a concept for organismic systems biology. Sem Cancer Biol. 2011;21(3):156–164
    1. Steiner R. Philosophy and anthroposophy (1904-1918) Whitefish: Kessinger Publishing, LLC; 2005
    1. Steiner R. Monism and the philosophy of spiritual activity Whitefish, MT: Kessinger Publishing; 2010
    1. Steiner R. The philosophy of freedom: the basis for a modern world conception (1894) Forrest Row, UK: Rudolf Steiner Press; 2006
    1. Steiner R. Der Kernpunkte der Sozialen Frage in den Lebensnotwendigkeiten der Gegenwart und Zukunft (1919). Dornach, Switzerland: Rudolf Steiner Verlag; 1976
    1. Steiner R. Aufsätze über die Dreigliederung des sozialen Organismus und zur Zeitlage 1915-1921 Dornach, Switzerland: Rudolf Steiner Verlag; 1982
    1. Abouleish I. Sekem: A sustainable community in the Egyptian Desert Edinburgh, Scotland: Floris Books; 2005
    1. Steiner R. Spiritual science and medicine (1920) Forrest Row, UK: Rudolf Steiner Press; 1989
    1. Steiner R, Wegman I. Fundamentals of therapy (1925) Forrest Row, UK: Rudolf Steiner Press; 1967
    1. Schwab JH, Murphy JB, Andersson P, et al.Eurythmy therapy in anxiety—a case report. Altern Ther Health Med. 2011;17(4):58–65
    1. Heusser PH. Akademische Forschung in der Anthroposophischen Medizin Beispiel Hygiogenese: Natur- und geisteswissenschaftliche Zugänge zur Selbstheilungskraft des Menschen. Bern, Switzerland: Peter Lang AG; 1999
    1. Antonovsky A. Salutogenese Tübingen, Germany: Dgvt Verlag; 1997
    1. Gutenbrunner C, Hildebrandt G, Moog R, et al.Chronobiology and Chronomedicine: Basic Research and Applications. Proceedings of the 7th Annual Meeting of the European Society for Chronobiology, Marburg 1991 Frankfurt am Main, Berlin: Peter Lang; 1991
    1. Girke M. Innere Medizin Grundlagen und therapeutische Konzepte der Anthroposophischen Medizin. Berlin: Salumed-Verlag GmbH; 2010
    1. Soldner G, Stellmann HM. Individuelle Pädiatrie: Leibliche, seelische und geistige Aspekte in Diagnostik und Beratung Anthroposophisch-homöopathische Therapie. Stuttgart: Wissenschaftliche Verlagsgesellschaft; 2007
    1. Institute of Medicine Integrative medicine and the health of the public: a summary of the February 2009 summit Washington, DC: The National Academies Press; 2009
    1. Burkhardt R, Kienle G: Die Zulassung von Arneimitteln und der Widerruf von Zulassungen nach dem Arzneimittelgesetz von 1976; Stuttgart: Verlag Urachhaus; 1982
    1. Hauschka M. Zur künstlerischen Therapie Bd.II. Wesen und Aufgabe der Maltherapie Nürnberg, Germany: Karl Ulrich & Co; 1991
    1. Mees-Christeller E. Künstlerische Therapie ausgewählter Krankheitsbilder. Merkurstab. 1995;3:261–269
    1. Steiner R. Curative eurythmy (1921). Bristol, UK: Rudolf Steiner Press; 1983
    1. Kirchner-Bockholt M. Fundamental principles of curative eurythmy London: Temple Lodge Press; 1977
    1. Ritchie J, Wilkinson J, Gantley M, et al.A model of integrated primary care: anthroposophic medicine January 2011: the seven-practice study. Accessed October 15, 2013
    1. Hamre HJ, Fischer M, Heger M, et al.Anthroposophic vs conventional therapy of acute respiratory and ear infections: a prospective outcomes study. Wien Klin Wochenschr. 2005;117(7-8):258–68
    1. Ziegler R. Mistletoe preparation Iscador: are there methodological concerns with respect to controlled clinical trials? Evid Based Complement Alternat Med. 2009March;6(1):19–30
    1. Kienle GS, Glockmann A, Grugel R, et al.Klinische Forschung zur Anthroposophischen Medizin—Update eines Health Technology Assessment-Berichts und Status Quo. Forsch Komplementmed. 2011;18:269–82
    1. Hekal IA, Samer T, Ibrahim EI. Viscum Fraxini 2, as an adjuvant therapy after resection of superficial bladder cancer: prospective clinical randomized study. Presented at the43rd Annual Congress of The Egyptian Urological Association in conjunction with The European Association of Urology November 10-14, 2008, Hurghada, Egypt Abstract P8. 120 2009
    1. Molassiotis A, Fernandez-Ortega P, Pud D, et al.Use of complementary and alterna-tive medicine in cancer patients: a European survey. Ann Oncol. 2005;16(4):655–63
    1. Fasching PA, Thiel F, Nicolaisen-Murmann K, et al.Association of complementary methods with quality of life and life satisfaction in patients with gynecologic and breast malignancies. Support Care Cancer. 2007;55(11):1277–84
    1. Kienle GS, Kiene H. Die Mistel in der Onkologie: Fakten und konzeptionelle Grundlagen Stuttgart, NY: Schattauer Verlag; 2003
    1. Büssing A, editor Mistletoe: the genus Viscum Amsterdam: Hardwood Academic Publishers; 2000
    1. Orhan DD, Kupeli E, Yesilada E, et al.Anti-inflammatory and antinociceptive activity of flavonoids isolated from Viscum album ssp. album. Z Naturforsch C. 2006;61(1-2):26–30
    1. Winkler K, Leneweit G, Schubert R. Characterization of membrane vesicles in plant extracts. Colloids Surf B Biointerfaces. 2005;45(2):57–65
    1. Jager S, Winkler K, Pfuller U, et al.Solubility studies of oleanolic acid and betulinic acid in aqueous solutions and plant extracts of Viscum album L. Planta Med. 2007;73(2):157–162
    1. Eggenschwiler J, von BL, Stritt B, et al.Mistletoe lectin is not the only cytotoxic component in fermented preparations of Viscum album from white fir (Abies pectina-ta). BMC Complement Altern Med. 2007May10;7:14.
    1. Büssing A, Schietzel M. Apoptosis-inducing properties of Viscum album L. extracts from different host trees, correlate with their content of toxic mistletoe lectins. Anticancer Res. 1999;19(1A):23–8
    1. Elsässer-Beile U, Lusebrink S, Grussenmeyer U, et al.Comparison of the effects of various clinically applied mistletoe preparations on peripheral blood leukocytes. Arzneim Forsch/Drug Res. 1998;48(II)(12):1185–9
    1. Valentiner U, Pfüller U, Baum C, et al.The cytotoxic effect of mistletoe lectins I, II and III on sensitive and multidrug resistant human colon cancer cell lines in vitro. Toxicology. 2002;171(2-3):187–99
    1. Siegle I, Fritz P, McClellan M, et al.Combined cytotoxic action of Viscum album agglutinin-1 and anticancer agents against human A549 lung cancer cells. Anticancer Res. 2001;21(4A):2687–91
    1. Bantel H, Engels IH, Voelter W, et al.Mistletoe lectin activates caspase-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis. Cancer Res. 1999;59:2083–90
    1. Mueller EA, Anderer FA. Synergistic action of a plant rhamnogalacturonan enhancing antitumor cytotoxicity of human natural killer and lymphokine-activated killer cells: Chemical specificity of target cell recognition. Cancer Res. 1990;50:3646–51
    1. Zhu HG, Zollner TM, Klein-Franke A, et al.Enhancement of MHC-unrestricted cyto-toxic activity of human CD56+CD3-natural killer (NK) cells and CD+T cells by rhamnogalacturonan: target cell specificity and activity against NK-insensitive targets. J Cancer Res Clin Oncol. 1994;(120):383–8
    1. Kienle GS, Kiene H. Influence of Viscum album L (European mistletoe) extracts on quality of life in cancer patients: a systematic review of controlled clinical studies. Integr Cancer Ther. 2010;9(2):142–57
    1. Kienle GS, Berrino F, Büssing A, et al.Mistletoe in cancer—a systematic review on controlled clinical trials. Eur J Med Res. 2003;8(3):109–19
    1. Kienle GS, Kiene H. Complementary cancer therapy: a systematic review of prospective clinical trials on anthroposophic mistletoe extracts. Eur J Med Res. 2007;12(3):103–19
    1. Tröger W, Galun D, Reif M, Schumann A, Stankovic N, Milicevic M. Viscum album [L.] extract therapy in patients with locally advanced or metastatic pancreatic cancer: a randomised clinical trial on overall survival. Eur J Cancer. 2013; In press
    1. Kienle GS, Glockmann A, Schink M, et al.Viscum album L. extracts in breast and gynaecologic cancers: a systematic review of clinical and preclinical research. J Exp Clin Cancer Res. 2009June11;28:79.
    1. Mabed M, El-Helw L, Sharma S. Phase II study of viscum fraxini-2 in patients with advanced hepatocellular carcinoma. Br J Cancer. 2004;90(1):65–9
    1. Matthes H, Buchwald D, Schad F, et al.Treatment of inoperable pancreatic carcinoma with combined intratumoral mistletoe therapy. Gastroenterology. 2005;128(4 Suppl 2):433.
    1. Orange M, Fonseca M, Lace A, et al.Durable tumour responses following primary high dose induction with mistletoe extracts: two case reports. Eur J Integr Med. 2010;2(2):63–9
    1. Orange M, Lace A, Fonseca M, et al.Durable regression of primary cutaneous B-cell lymphoma following fever-inducing mistletoe treatment—two case reports. Global Adv Health Med. 2012;1(1):16–23
    1. Werthmann P, Sträter G, Friesland H, et al.Durable response of cutaneous squamous cell carcinoma following high-dose perilesional injections of Viscum album extracts—a case report. Phytomedicine. 2013;20(3-4):324–7
    1. Kienle GS, Grugel R, Kiene H. Safety of higher dosages of Viscum album L. in ani-mals and humans - systematic review of immune changes and safety parameters. BMC Complement Altern Med. 2011;11(1):72
    1. Hamre HJ, Becker-Witt C, Glockmann A, Ziegler R, Willich SN, Kiene H. Anthroposophic therapies in chronic disease: the Anthroposophic Medicine Outcome Study (AMOS). Eur J Med Res. 2004;9(7):351–360
    1. Hamre HJ, Witt CM, Kienle GS, et al.Anthroposophic therapy for children with chronic disease: a two-year prospective cohort study in routine outpatient settings. BMC Pediatr 2009June19;9:39.
    1. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Eurythmy therapy in chronic disease: a four-year prospective cohort study. BMC Public Health 2007April23;7:61.
    1. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Anthroposophic art therapy in chronic disease: a four-year prospective cohort study. Explore NY. 2007;3(4):365–71
    1. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Rhythmical massage therapy in chronic disease: a 4-year prospective cohort study. J Altern Complement Med. 2007;13(6):635–42
    1. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Anthroposophic medical therapy in chronic disease: a four-year prospective cohort study. BMC Complement Altern Med 2007April23;7:10.
    1. Hamre HJ, Witt CM, Glockmann A, et al.Outcome of anthroposophic medication therapy in chronic disease: a 12-month prospective cohort study. Drug Des Devel Ther. 2009February6;2:25–37
    1. Hamre HJ, Witt CM, Kienle GS, et al.Anthroposophic therapy for children with attention deficit hyperactivity: a two-year prospective study in outpatients. Int J Gen Med. 2010August30;3:239–53
    1. Hamre HJ, Witt CM, Kienle GS, et al.Anthroposophic therapy for anxiety disorders: a two-year prospective cohort study in routine outpatient settings. Clin Med Insights: Psychiatry. 2009;2:17–31
    1. Hamre HJ, Witt CM, Kienle GS, et al.Anthroposophic therapy for asthma: a two-year prospective cohort study in routine outpatient settings. J Asthma Allergy. 2009November24;2:111–28
    1. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Anthroposophic therapy for chronic depression: a four-year prospective cohort study. BMC Psychiatry. 2006December15;6:57.
    1. Hamre HJ, Witt CM, Glockmann A, et al.Anthroposophic vs conventional therapy for chronic low back pain: a prospective comparative study. Eur J Med Res. 2007;12(7):302–10
    1. Hamre HJ, Witt CM, Kienle GS, et al.Long-term outcomes of anthroposophic therapy for chronic low back pain: A two-year follow-up analysis. J Pain Res. 2009June25;2:75–85
    1. Hamre HJ, Witt CM, Kienle GS, et al.Anthroposophic therapy for migraine: a two-year prospective cohort study in routine outpatient settings. Open Neurol J. 2010;4:100–10
    1. Hamre HJ, Glockmann A, Tröger W, Kienle GS, Kiene H. Assessing the order of magnitude of outcomes in single-arm cohorts through systematic comparison with corresponding cohorts: an example from the AMOS study. BMC Med Res Methodol. 2008;8:11.
    1. Hamre HJ, Glockmann A, Kienle GS, Kiene H. Combined bias suppression in single-arm therapy studies. J Eval Clin Pract. 2008;14(5):923–9
    1. Heusser P, Braun SB, Ziegler R, et al.Palliative inpatient cancer treatment in an anthroposophic hospital: I. Treatment patterns and compliance with anthroposophic medicine. Forsch Komplementmed. 2006;13(2):94–100
    1. Heusser P, Berger Braun S, Bertschy M, et al.Palliative inpatient cancer treatment in an anthroposophic hospital: II. Quality of life during and after stationary treatment, and subjective treatment benefits. Forsch Komplementmed 2006;13(3):156–66
    1. von Rohr E, Pampallona S, van Wegberg B, et al.Experiences in the realisation of a research project on anthroposophical medicine in patients with advanced cancer. Schweiz Med Wochenschr. 2000;130(34):1173–84
    1. von Rohr E, Pampallona S, van Wegberg B, et al.Attitudes and beliefs towards disease and treatment in patients with advanced cancer using anthroposophical medicine. Onkologie 2000;23:558–563
    1. Carlsson M, Arman M, Backman M, Flatters U, Hatschek T, Hamrin E. Evaluation of quality of life/life satisfaction in women with breast cancer in complementary and conventional care. Acta Oncol. 2004;43(1):27–34
    1. Carlsson M, Arman M, Backman M, Flatters U, Hatschek T, Hamrin E. A five-year follow-up of quality of life in women with breast cancer in anthroposophic and conventional care. Evid Based Complement Alternat Med 2006;3(4):523–31
    1. Simon L. Ein anthroposophisches Therapiekonzept für entzündlich-rheumatische Erkrankungen. Ergebnisse einer zweijährigen Pilotstudie. Forsch Komplementmed. 1997;4:17–27
    1. Astrup C, Astrup Sv, Astrup S, et al.Die Behandlung von Gesichtsschmerzen mit homöopathischen Heilmitteln. Erfahrungsheilkunde. 1976;3:89–96
    1. Schäfer PM: Katamnestische Untersuchung zur Anorexia nervosa In: Bissegger M, editor Die Behandlung von Magersucht: ein integrativer Therapieansatz. Stuttgart: Verlag Freies Geistesleben; 1998:130–60
    1. Huber R, Lüdtke R, Klassen M, et al.Effects of a mistletoe preparation with defined lectin content on chronic hepatitis C: an individually controlled cohort study. Eur J Med Res. 2001;6(9):399–405
    1. Tusenius KJ, Spoek JM, Kramers CW. Iscador Qu for chronic hepatitis C: an exploratory study. Complement Ther Med. 2001;9(1):12–6
    1. Tusenius KJ, Spoek AM, van HJ. Exploratory study on the effects of treatment with two mistletoe preparations on chronic hepatitis C. Arzneimittelforschung. 2005;55(12):749–53
    1. Huyke C, Laszczyk K, Scheffler A, et al.Behandlung aktinischer Keratose mit Birkenkorkenextrakt: Eine Pilotstudie. J Dtsch Dermatol Ges. 2006;4(2):132–6
    1. Huyke C, Reuter J, Rodig M, et al.Treatment of actinic keratoses with a novel betulin-based oleogel. A prospective, randomized, comparative pilot study. J Dtsch Dermatol Ges. 2008
    1. Ostermann T, Blaser G, Bertram M, Michalsen A, Matthiessen PF, Kraft K. Effects of rhythmic embrocation therapy with solum oil in chronic pain patients: a prospective observational study. Clin J Pain. 2008;24(3):237–43
    1. Baars EW, Gans S, Ellis EL. The effect of hepar magnesium on seasonal fatigue symptoms: a pilot study. J Altern Complement Med. 2008;14(4):395–402
    1. Guala A, Pastore G, Garipoli V, Agosti M, Vitali M, Bona G. The time of umbilical cord separation in healthy full-term newborns: a controlled clinical trial of different cord practices. Eur J Pediatr. 2003;162(5):350–1
    1. Janke S, Seidler A, Schmidt E. Schnellere Nabelheilung durch WecesinÒ Streupuder. Die Hebamme. 1997;10:115–7
    1. Majorek M, Tüchelmann T, Heusser P. Therapeutic eurythmy—movement therapy for children with attention deficit hyperactivity disorder (ADHD): a pilot study. Complement Ther Nurs Midwifery. 2004February;10(1):46–53
    1. Ulbricht M. Antipyretische Wirkung eines körperwarmen Einlaufes. Inaugural-Dissertation. Tübingen; 1991
    1. Gärtner C. Therapie der Arthrosen grosser Gelenke. Merkurstab. 1999;1:48–51
    1. Gärtner C. Der akute muskuläre Okzipitalschmerz. Therapiestudie mit lokalen Infil-trationen Gelsemium compositum. Merkurstab. 1999;4:244–9
    1. Krabbe AA, Olesen J. Ferrumkvarts som profylaktikum ved migræne. En dobbelt-blind undersøgelse. Ugeskr Laeger. 1980;142(8):516–8
    1. Jeffrey SLA, Belcher JC. Use of Arnica to relieve pain after carpal-tunnel release surgery. Altern Ther Health Med. 2002;8(2):66–8
    1. Pach D, Brinkhaus B, Roll S, et al.Efficacy of injections with Disci/Rhus Toxicodendron Compositum for chronic low back pain—a randomized placebo-controlled trial. PLoS ONE. 2011;6(11):e26166.
    1. Huber R, Prestel U, Bloss I, Meyer U, Lüdtke R. Effectiveness of subcutaneous in-jections of a cartilage preparation in osteoarthritis of the knee—a randomized, placebo controlled phase II study. Complement Ther Med. 2010;18(3):113–8
    1. Sharp L, Finnilä K, Johansson H, Abrahamsson M, Hatschek T, Bergenmar M. No differences between Calendula cream and aqueous cream in the prevention of acute radiation skin reactions—results from a randomised blinded trial. Eur J Oncol Nurs. 2013August;17(4):429–35
    1. von Hagens C, Schiller P, Godbillon B, et al.Treating menopausal symptoms with a complex remedy or placebo: a randomized controlled trial. Climacteric 2012;15(4):358–67
    1. Esch BM, Marian F, Busato A, Huesser P. Patient satisfaction with primary care: an observational study comparing anthroposophic and conventional care. Health Qual Life Outcomes. 2008;6(1):74.
    1. Koster EB, Ong RRS, Heybroek-Bellwinkel R, et al.CQ-Index Antroposofische Gezondheidszorg Constructie en validering. Leiden: Lectoraat Antroposofische Gezondheidszorg; 2012
    1. Hamre HJ, Witt CM, Glockmann A, Tröger W, Willich SN, Kiene H. Use and safety of anthroposophic medications in chronic disease: a 2-year prospective analysis. Drug Saf. 2006;29(12):1173–89
    1. Baars EW, Adriaansen-Tennekes R, Eikmans KJ. Safety of homeopathic injectables for subcutaneous administration: a documentation of the experience of prescribing practitioners. J Altern Complement Med. 2005;11(4):609–16
    1. Hamre HJ, Glockmann A, Fischer M, et al.Use and safety of anthroposophic medications for acute respiratory and ear infections: a prospective cohort study. Drug Target Insights. 2007;2:209–19
    1. Jeschke E, Ostermann T, Luke C, et al.Remedies containing Asteraceae extracts: a prospective observational study of prescribing patterns and adverse drug reactions in German primary care. Drug Saf. 2009;32(8):691–706
    1. Plangger N, Rist L, Zimmermann R, von Mandach U. Intravenous tocolysis with Bryophyllum pinnatum is better tolerated than beta-agonist application. Eur J Obstet Gynecol Reprod Biol. 2006;124(2):168–72
    1. Hamre HJ, Witt CM, Glockmann A, et al.Health costs in patients treated for depression, in patients with depressive symptoms treated for another chronic disorder, and in non-depressed patients: a two-year prospective cohort study in anthroposophic outpatient settings. Eur J Health Econ. 2010;11(1):77–94
    1. Hamre HJ, Witt CM, Glockmann A, Ziegler R, Willich SN, Kiene H. Health costs in anthroposophic therapy users: a two-year prospective cohort study. BMC Health Services Research. 2006;6:65.
    1. Studer HP, Busato A. Comparison of Swiss basic health insurance costs of complementary and conventional medicine. Forsch Komplementmed. 2011;18(6):315–20
    1. Studer HP, Busato A. Development of costs for complementary medicine after provisional inclusion into the Swiss basic health insurance. Forsch Komplementmed. 2011;18(1):15–23
    1. Kooreman P, Baars EW. Patients whose GP knows complementary medicine tend to have lower costs and live longer. Eur J Health Econ. 2012December;13(6):769–76
    1. Kienle GS. Why medical case reports? Global Adv Health Med. 2012;1(1):8–9
    1. Kienle GS, Kiene H. Clinical judgement and the medical profession. J Eval Clin Pract. 2011;17(4):621–7
    1. Kiene H, Schön-Angerer T. Single-case causality assessment as a basis for clinical judgment. Altern Ther Health Med. 1998;4(1):41–47
    1. Kiene H. Komplementäre Methodenlehre der klinischen Forschung Cognition-based Medicine. Berlin, Heidelberg, NY: Springer-Verlag; 2001
    1. Kiene H, Hamre HJ, Kienle GS. In support of clinical case reports: a system of causality assessment. Global Adv Health Med. 2013;2(2):28–39
    1. Wode K, Schneider T, Lundberg I, Kienle GS. Mistletoe treatment in cancer-related fatigue: a case report. Cases J. 2009January22;2(1):77.
    1. Kienle GS, Meusers M, Quecke B, Hilgard D. Patient-centered diabetes care in children: an integrated, individualized, systems-oriented, and Multidisciplinary Approach. Global Adv Health Med 2013;2(2):12–19

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