Avoidable Adverse Events Related to Ignoring the Do-Not-Do Recommendations: A Retrospective Cohort Study Conducted in the Spanish Primary Care Setting

José Joaquín Mira, Irene Carrillo, Pastora Pérez-Pérez, Maria Pilar Astier-Peña, Johanna Caro-Mendivelso, Guadalupe Olivera, Carmen Silvestre, Mª Angeles Nuín, Jesús M Aranaz-Andrés, on behalf the SOBRINA Research Team, José Joaquín Mira, Irene Carrillo, Pastora Pérez-Pérez, Maria Pilar Astier-Peña, Johanna Caro-Mendivelso, Guadalupe Olivera, Carmen Silvestre, Mª Angeles Nuín, Jesús M Aranaz-Andrés, on behalf the SOBRINA Research Team

Abstract

Objective: This study aimed to measure the frequency and severity of avoidable adverse events (AAEs) related to ignoring do-not-do recommendations (DNDs) in primary care.

Methods: A retrospective cohort study analyzing the frequency and severity of AAEs related to ignoring DNDs (7 from family medicine and 3 from pediatrics) was conducted in Spain. Data were randomly extracted from computerized electronic medical records by a total of 20 general practitioners and 5 pediatricians acting as reviewers; data between February 2018 and September 2019 were analyzed.

Results: A total of 2557 records of adult and pediatric patients were reviewed. There were 1859 (72.7%) of 2557 (95% confidence interval [CI], 71.0%-74.4%) DNDs actions in 1307 patients (1507 were performed by general practitioners and 352 by pediatricians). Do-not-do recommendations were ignored more often in female patients (P < 0.0001). Sixty-nine AAEs were linked to ignoring DNDs (69/1307 [5.3%]; 95% CI, 4.1%-6.5%). Of those, 54 (5.1%) of 1062 were in adult patients (95% CI, 3.8%-6.4%) and 15 (6.1%) of 245 in pediatric patients (95% CI, 3.1%-9.1%). In adult patients, the majority of AAEs (51/901 [5.7%]; 95% CI, 4.2%-7.2%) occurred in patients 65 years or older. Most AAEs were characterized by temporary minor harm both in adult patients (28/54 [51.9%]; 95% CI, 38.5%-65.2%) and pediatric patients (15/15 [100%]).

Conclusions: These findings provide a new perspective about the consequences of low-value practices for the patients and the health care systems. Ignoring DNDs could place patients at risk, and their safety might be unnecessarily compromised.

Trial registration number: NCT03482232.

Conflict of interest statement

The authors diclose no conflict of interest.

Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc.

Figures

FIGURE 1
FIGURE 1
Flowchart of study phases and main outcomes.

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Source: PubMed

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