Typhoid fever among hospitalized febrile children in Siem Reap, Cambodia

Lalith P M Wijedoru, Varun Kumar, Ngoun Chanpheaktra, Kheng Chheng, Henk L Smits, Rob Pastoor, Tran Vu Thieu Nga, Stephen Baker, Vanaporn Wuthiekanun, Sharon J Peacock, Hor Putchhat, Christopher M Parry, Lalith P M Wijedoru, Varun Kumar, Ngoun Chanpheaktra, Kheng Chheng, Henk L Smits, Rob Pastoor, Tran Vu Thieu Nga, Stephen Baker, Vanaporn Wuthiekanun, Sharon J Peacock, Hor Putchhat, Christopher M Parry

Abstract

Typhoid fever was confirmed by positive blood culture in 5 (3.7%) of 134 febrile children hospitalized in Cambodia. Typhoid was suspected in an additional 25 (18.7 %) blood culture-negative children based on: a positive immunoglobulin M lateral flow assay (IgMFA) (16); a positive polymerase chain reaction (PCR) for Salmonella typhi (2); or clinical assessment (7). The specificity of the IgMFA and PCR assays requires further study.

References

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Source: PubMed

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