Body weight, body composition and energy balance related behaviour during the transition to parenthood: study protocol of a multi-centre observational follow-up study (TRANSPARENTS)

Tom Deliens, Vickà Versele, Hannelore Vanden Eynde, Peter Clarys, Roland Devlieger, Annick Bogaerts, Leonardo Gucciardo, Annick Schreurs, Caroline Van Holsbeke, Dirk Aerenhouts, Tom Deliens, Vickà Versele, Hannelore Vanden Eynde, Peter Clarys, Roland Devlieger, Annick Bogaerts, Leonardo Gucciardo, Annick Schreurs, Caroline Van Holsbeke, Dirk Aerenhouts

Abstract

Background: The transition to parenthood is a cornerstone event for both parents, potentially leading to relevant changes in lifestyle and behaviour. In women, the metabolic changes during and after pregnancy and the deleterious effects of excessive gestational weight gain and postpartum weight retention have been extensively described. However, there is no full understanding about which specific energy balance related behaviours (EBRB) contribute to unfavourable weight gain and weight retention. Furthermore, information on how transition to parenthood affects men is lacking. Therefore, this study aims to investigate changes in body weight, body composition and EBRB in couples transitioning to parenthood.

Methods: TRANSPARENTS is a multi-centre observational follow-up study that focuses on body weight, body composition and EBRB during the transition to parenthood. Couples (women and men) will be recruited during the first trimester of their first pregnancy. Study visits will occur at four occasions (12 weeks of pregnancy, 6 weeks postpartum, 6 months postpartum and 12 months postpartum). Anthropometrics of the parents and new-borns will be assessed including body weight, height/length, body composition (using bio-electrical impedance analysis and measurement of four skinfold thicknesses (biceps, triceps, subscapular and supraspinal/suprailiac)) and waist and hip circumference. Dietary intake, physical activity, sedentary behaviour, smoking habits, sleeping pattern, fatigue, diet and exercise related partner support, mental health, breastfeeding, contraception use, and socio-demographics will be assessed using a questionnaire. In addition, accelerometry will be used to assess physical activity and sedentary behaviour objectively. Also data from women's medical record, such as pre-pregnancy weight and pregnancy outcomes, will be included. Multilevel modelling will be used to evaluate maternal and paternal changes in body weight, body composition and EBRB during and after pregnancy (primary outcomes). Multiple linear regression analyses will be performed to identify predictors of changes in body weight, body composition and EBRB. All analyses will be adjusted for possible confounders.

Discussion: TRANSPARENTS is a unique project identifying vulnerable parents and (un)favourable changes in EBRB throughout this potentially critical life period. Provided insights will facilitate the development of effective intervention strategies to help couples towards a healthy transition to parenthood.

Trial registration: Clinicaltrials.gov Identifier: NCT03454958. Registered March 2018.

Keywords: Body composition; Energy balance related behaviour; Parenthood; Pregnancy.

Conflict of interest statement

Ethics approval and consent to participate

The trial will be conducted in compliance with the principles of the Declaration of Helsinki (current version), the principles of good clinical practice (GCP) and in accordance with all applicable regulatory requirements. The protocol and related documents were submitted for review and approved by the leading Medical Ethics Committee of the University Hospital of the Vrije Universiteit Brussel (UZ Brussel, Brussels, Belgium) on May 16th 2018 (B.U.N. 143201835875). This approval includes the advices of the non-leading Medical Ethics Committees of the participating hospitals, i.e. UZ Leuven (KULeuven), Jessa Ziekenhuis Hasselt and Ziekenhuis Oost-Limburg Genk. In addition, an amendment of the protocol was submitted for review and approved by the same leading Medical Ethics Committee on October 29th 2018. Any other amendments will be communicated with the leading Medical Ethics Committee. The study can and will be conducted only on the basis of prior written informed consent by the subjects to participate in the study. All data will be coded, the subjects’ names or other identifiers will be stored separately from the research data and replaced by unique codes to create new identities for each individual subject. Only researchers involved in the study will have access to the data.

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
Timeline of the TRANSPARENTS observational follow-up study

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