Seminal Plasma Activity to Improve Implantation in In Vitro Fertilization-How Can It Be Used in Daily Practice?

Frank Nawroth, Michael von Wolff, Frank Nawroth, Michael von Wolff

No abstract available

Keywords: implantation; in vitro fertilization; intracervical; intravaginal; seminal plasma; sperm preparation.

References

    1. Saccone G, Sardo A, Ciardulli A, Caissutti C, Spinelli M, Surbek D, et al. Effectiveness of seminal plasma in IVF treatment: a systematic review and meta-analysis. BJOG (2017).10.1111/1471-0528.15004
    1. Crawford G, Ray A, Gudi A, Shah A, Homburg R. The role of seminal plasma for improved outcomes during in vitro fertilization treatment: review of the literature and meta-analysis. Hum Reprod Update (2015) 21:275–84.10.1093/humupd/dmu052
    1. von Wolff M, Nowak O, Pinheiro RM, Strowitzki T. Seminal plasma – immunomodulatory potential in men with normal and abnormal sperm count. Eur J Obstet Gynecol Reprod Biol (2007) 134:73–8.10.1016/j.ejogrb.2007.01.009
    1. von Wolff M, Rösner S, Germeyer A, Jauckus J, Griesinger G, Strowitzki T. Intrauterine instillation of diluted seminal plasma at oocyte pick-up does not increase the IVF pregnancy rate: a double-blind, placebo controlled, randomized study. Hum Reprod (2013) 28:3247–52.10.1093/humrep/det351
    1. Gutsche S, von Wolff M, Strowitzki T, Thaler CJ. Seminal plasma induces mRNA expression of IL-1beta, IL-6 and LIF in endometrial epithelial cells in vitro. Mol Hum Reprod (2003) 9:785–91.10.1093/molehr/gag095
    1. Horcajadas JA, Riesewijk A, Polman J, van Os R, Pellicer A, Mosselman S, et al. Effect of controlled ovarian hyperstimulation in IVF on endometrial gene expression profiles. Mol Hum Reprod (2005) 11:195–205.10.1093/molehr/gah150
    1. Schjenken JE, Robertson SA. Seminal fluid signalling in the female reproductive tract: implications for reproductive success and offspring health. Adv Exp Med Biol (2015) 868:127–58.10.1007/978-3-319-18881-2_6
    1. Robertson SA, Ingman WV, O’Leary S, Sharkey DJ, Tremellen KP. Transforming growth factor beta – a mediator of immune deviation in seminal plasma. J Reprod Immunol (2002) 57:109–28.10.1016/S0165-0378(02)00015-3
    1. Clark DA, Fernandes J, Banwatt D. Prevention of spontaneous abortion in the CBA x DBA/2 mouse model by intravaginal TGF-beta and local recruitment of CD4+8+ FOXP3+ cells. Am J Reprod Immunol (2008) 59:525–34.10.1111/j.1600-0897.2008.00582.x
    1. Sharkey DJ, Macpherson AM, Tremellen KP, Mottershead DG, Gilchrist RB, Robertson SA. TGF beta mediates proinflammatory seminal fluid signaling in human cervical epithelial cells. J Immunol (2012) 189:1024–35.10.4049/jimmunol.1200005
    1. Tremellen KP, Valbuena D, Landeras J, Ballesteros A, Martinez J, Mendoza S, et al. The effect of intercourse on pregnancy rates during assisted human reproduction. Hum Reprod (2000) 15:2653–8.10.1093/humrep/15.12.2653
    1. von Wolff M, Rösner S, Thöne C, Pinheiro RM, Jauckus J, Bruckner T, et al. Intravaginal and intracervical application of seminal plasma in in vitro fertilization or intracytoplasmic sperm injection treatment cycles – a double-blind, placebo-controlled, randomized pilot study. Fertil Steril (2009) 91:167–72.10.1016/j.fertnstert.2007.11.036
    1. Huleihel M, Lunenfeld E, Levy A, Potashnik G, Glezerman M. Distinct expression levels of cytokines and soluble cytokine receptors in seminal plasma of fertile and infertile men. Fertil Steril (1996) 66:135–9.10.1016/S0015-0282(16)58401-5

Source: PubMed

3
Suscribir