Socket preservation by beta-tri-calcium phosphate with collagen compared to platelet-rich fibrin: A clinico-radiographic study

Swati Das, Rajesh Jhingran, Vivek Kumar Bains, Rohit Madan, Ruchi Srivastava, Iram Rizvi, Swati Das, Rajesh Jhingran, Vivek Kumar Bains, Rohit Madan, Ruchi Srivastava, Iram Rizvi

Abstract

Objectives: This study was primarily designed to determine the clinico-radiographic efficacy of platelet-rich fibrin (PRF) and beta-tri-calcium phosphate with collagen (β-TCP-Cl) in preserving extraction sockets.

Materials and methods: For Group I (PRF), residual sockets (n = 15) were filled with autologous PRF obtained from patients' blood; and for Group II (β-TCP-Cl), residual sockets (n = 15) were filled with β-TCP-Cl. For the sockets randomly selected for Group II (β-TCP-Cl), the reshaped Resorbable Tissue Replacement cone was inserted into the socket.

Results: Clinically, there was a significantly greater decrease in relative socket depth, but apposition in midcrestal height in Group II (β-TCP-Cl) as compared to Group I (PRF), whereas more decrease in buccolingual width of Group I (PRF) than Group II (β-TCP-Cl) after 6 months. Radiographically, the mean difference in socket height, residual ridge, and width (coronal, middle, and apical third of socket) after 6 months was higher in Group I (PRF) as compared to Group II (β-TCP-Cl). The mean density (in Hounsfield Units) at coronal, middle, and apical third of socket was higher in Group I (PRF) as compared to Group II (β-TCP-Cl). There were statistically significant apposition and resorption for Group I (PRF) whereas nonsignificant resorption and significant apposition for Group II (β-TCP-Cl) in buccal and lingual/palatal cortical plate, respectively, at 6 months on computerized tomography scan.

Conclusion: The use of either autologous PRF or β-TCP-Cl was effective in socket preservation. Results obtained from PRF were almost similar to β-TCP-Cl; therefore being autologous, nonimmune, cost-effective, easily procurable regenerative biomaterial, PRF proves to be an insight into the future biofuel for regeneration.

Keywords: Beta-tricalcium phosphate; extraction socket; platelet-rich fibrin; type I collagen.

Figures

Figure 1
Figure 1
Flow chart: Study design
Figure 2
Figure 2
Root stump indicated for extraction
Figure 3
Figure 3
Platelet-rich fibrin obtained
Figure 4
Figure 4
Periotome in position (on mesial side) for extraction
Figure 5
Figure 5
Periotome in position (on distal side) for extraction
Figure 6
Figure 6
Platelet-rich fibrin in extraction socket
Figure 7
Figure 7
Beta-tricalcium phosphate with collagen (β- TCP-Cl) in extraction socket
Figure 8
Figure 8
Crisscross suture on socket
Figure 9
Figure 9
Clinical parameter recording
Figure 10
Figure 10
Cast model and line l and k for clinical measurement
Figure 11
Figure 11
(a) Computerized tomography scan image analysis, (b) preoperative computerized tomography scan image
Figure 12
Figure 12
Radiographic landmarks
Figure 13
Figure 13
Six months histologic images at ×10 for Group I (platelet-rich fibrin)
Figure 14
Figure 14
Six months histologic images at ×10 for Group II (β-tri-calcium phosphate with collagen)

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