Quality of Life in Caregivers of ADHD Children and Diabetes Patients

Elisa Meirelles Andrade, Laysa Minella Geha, Paula Duran, Raphael Suwwan, Felipe Machado, Maria Conceição do Rosário, Elisa Meirelles Andrade, Laysa Minella Geha, Paula Duran, Raphael Suwwan, Felipe Machado, Maria Conceição do Rosário

Abstract

Introduction: Studies have shown that the presence of attention-deficit hyperactivity disorder (ADHD) causes great impairment in academic, social, and professional activities as well as in the quality of life (QoL) of its patients. Similarly, the impact caused by other chronic disorders, such as diabetes, in the patient's QoL has been emphasized in many studies. Despite its relevance, no study has yet investigated whether ADHD caregivers and diabetic patients would have similar QoL impairment.

Objectives: This study was conducted in order to compare the QoL scores among ADHD caregivers and diabetic patients.

Methods: We evaluated 63 caregivers of ADHD children treated at the Child and Adolescent Psychiatric Unit at the Federal University of São Paulo (UPIA-UNIFESP) and 52 adult diabetic patients. Subjects were assessed with the World Health Organization quality of Life-Bref Version (WHOQOL-BREF), the Beck and Hamilton depression scales, and the Adult Self-Report Scale.

Results: When compared to the Brazilian normative data, ADHD caregivers had significantly lower scores in the social relations and environment WHOQOL domains. ADHD caregivers and diabetic patients had similar impairment in all WHOQOL domains except for the physical domain.

Conclusion: ADHD affects the QoL of the patient's caregiver, with similar impairment, when compared to the QoL of diabetic patients. These results emphasize the need for assessing QoL of the caregivers as part of the treatment strategies. They also emphasize the need for future studies with larger sample sizes comparing how the QOL is impacted in different chronic disorders.

Keywords: attention-deficit disorder and hyperactivity disorder; caregiver; children; diabetes; quality of life.

References

    1. Polanczyk G, de Lima MS, Horta BL, Biederman J, Rohde LA. The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry (2007) 164:942–8.10.1176/ajp.2007.164.6.942
    1. Willcutt EG. The prevalence of DSM-IV attention-deficit/hyperactivity disorder: a meta-analytic review. Neurotherapeutics (2012) 9:490–9.10.1007/s13311-012-0135-8
    1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders: DSM-5. Washington, DC: American Psychiatric Association; (2013).
    1. Harpin VA. The effect of ADHD on the life of an individual, their family, and community from preschool to adult life. Arch Dis Child (2005) 90(Suppl 1):i2–7.10.1136/adc.2004.059006
    1. Danckaerts M, Sonuga-Barke EJS, Banaschewski T, Buitelaar J, Döpfner M, Hollis C, et al. The quality of life of children with attention deficit/hyperactivity disorder: a systematic review. Eur Child Adolesc Psychiatry (2010) 19:83–105.10.1007/s00787-009-0046-3
    1. Johnston C, Mash EJ. Families of children with attention-deficit/hyperactivity disorder: review and recommendations for future research. Clin Child Fam Psychol Rev (2001) 4:183–207.10.1023/A:1017592030434
    1. Faraone SV, Biederman J, Chen WJ, Milberger S, Warburton R, Tsuang MT. Genetic heterogeneity in attention-deficit hyperactivity disorder (ADHD): gender, psychiatric comorbidity, and maternal ADHD. J Abnorm Psychol (1995) 104:334–45.10.1037/0021-843X.104.2.334
    1. Desidério RCS, Miyazaki MCOS. Transtorno de Déficit de Atenção/Hiperatividade (TDAH): orientações para a família. Psicol Esc e Educ (2007) 11:165–76.
    1. Göz F, Karaoz S, Goz M, Ekiz S, Cetin I. Effects of the diabetic patients’ perceived social support on their quality-of-life. J Clin Nurs (2007) 16:1353–60.10.1111/j.1365-2702.2007.01472.x
    1. Eiser C, Morse R. Quality-of-life measures in chronic diseases of childhood. Health Technol Assess (2001) 5:1–157.10.3310/hta5040
    1. Xiang Y-T, Luk ESL, Lai KYC. Quality of life in parents of children with attention-deficit-hyperactivity disorder in Hong Kong. Aust N Z J Psychiatry (2009) 43:731–8.10.1080/00048670903001968
    1. Coghill D. The impact of medications on quality of life in attention-deficit hyperactivity disorder: a systematic review. CNS Drugs (2010) 24:843–66.10.2165/11537450-000000000-00000
    1. Coghill D, Danckaerts M, Sonuga-Barke E, Sergeant J. Practitioner review: quality of life in child mental health – conceptual challenges and practical choices. J Child Psychol Psychiatry (2009) 50:544–61.10.1111/j.1469-7610.2009.02008.x
    1. Kim Y, Kim B, Chang J-S, Kim B-N, Cho S-C, Hwang J-W. Parental quality of life and depressive mood following methylphenidate treatment of children with attention-deficit hyperactivity disorder. Psychiatry Clin Neurosci (2014) 68(7):506–14.10.1111/pcn.12155
    1. Wändell PE. Quality of life of patients with diabetes mellitus. An overview of research in primary health care in the Nordic countries. Scand J Prim Health Care (2005) 23:68–74.10.1080/02813430510015296
    1. Miranzi SSC, Ferreira FS, Iwamoto HH, Pereira GA, Miranzi MAS. Qualidade de vida de indivíduos com Diabetes Mellitus e Hipertensão acompanhados por uma equipe de Saúde da Família. Texto Context Enferm (2008) 17:672–9.10.1590/S0104-07072008000400007
    1. Daniele TM, Bruin VM, Oliveira DS, Pompeu CM, Forti AC. Associations among physical activity, comorbidities, depressive symptoms and health-related quality of life in type 2 diabetes. Arq Bras Endocrinol Metabol (2013) 57:44–50.10.1590/S0004-27302013000100006
    1. Kiadaliri AA, Najafi B, Mirmalek-Sani M. Quality of life in people with diabetes: a systematic review of studies in Iran. J Diabetes Metab Disord (2013) 12:54.10.1186/2251-6581-12-54
    1. de Souza TT. Qualidade de vida da pessoa diabética. Rev Esc Enferm USP (1997) 31:150–64.
    1. Rubin RR, Peyrot M. Quality of life and diabetes. Diabetes Metab Res Rev (1999) 15:205–18.10.1002/(SICI)1520-7560(199905/06)15:3<205::AID-DMRR29>;2-O
    1. de Ornelas Maia AC, Braga Ade A, Paes F, Machado S, Carta MG, Nardi AE, et al. Comorbidity of depression and anxiety: association with poor quality of life in Type 1 and 2 diabetic patients. Clin Pract Epidemiol Ment Heal (2013) 9:136–41.10.2174/1745017901309010136
    1. Sawyer MG, Whaites L, Rey JM, Hazell PL, Graetz BW, Baghurst P. Health-related quality of life of children and adolescents with mental disorders. J Am Acad Child Adolesc Psychiatry (2002) 41:530–7.10.1097/00004583-200205000-00010
    1. Escobar R, Soutullo CA, Hervas A, Gastaminza X, Polavieja P, Gilaberte I. Worse quality of life for children with newly diagnosed attention-deficit/hyperactivity disorder, compared with asthmatic and healthy children. Pediatrics (2005) 116:e364–9.10.1542/peds.2005-0386
    1. Akvardar Y, Akdede BB, Ozerdem A, Eser E, Topkaya S, Alptekin K. Assessment of quality of life with the WHOQOL-BREF in a group of Turkish psychiatric patients compared with diabetic and healthy subjects. Psychiatry Clin Neurosci (2006) 60:693–9.10.1111/j.1440-1819.2006.01584.x
    1. Klassen AF, Miller A, Fine S. Agreement between parent and child report of quality of life in children with attention-deficit/hyperactivity disorder. Child Care Health Dev (2006) 32:397–406.10.1111/j.1365-2214.2006.00609.x
    1. Moreira H, Carona C, Silva N, Frontini R, Bullinger M, Canavarro MC. Psychological and quality of life outcomes in pediatric populations: a parent-child perspective. J Pediatr (2013) 163:1471–8.10.1016/j.jpeds.2013.06.028
    1. Cussen A, Sciberras E, Ukoumunne OC, Efron D. Relationship between symptoms of attention-deficit/hyperactivity disorder and family functioning: a community-based study. Eur J Pediatr (2012) 171:271–80.10.1007/s00431-011-1524-4
    1. Pongwilairat K, Louthrenoo O, Charnsil C, Witoonchart C. Quality of life of children with attention-deficit/hyper activity disorder. J Med Assoc Thai (2005) 88:1062–6.
    1. Coghill D, Spiel G, Baldursson G, Döpfner M, Lorenzo MJ, Ralston SJ, et al. Which factors impact on clinician-rated impairment in children with ADHD? Eur Child Adolesc Psychiatry (2006) 15(Suppl 1):I30–7.10.1007/s00787-006-1005-x
    1. Chen VC-H, Yeh C-J, Lee T-C, Chou J-Y, Shao W-C, Shih D-H, et al. Symptoms of attention deficit hyperactivity disorder and quality of life of mothers of school-aged children: the roles of child, mother, and family variables. Kaohsiung J Med Sci (2014) 30:631–8.10.1016/j.kjms.2014.09.001
    1. Gormez V, Forbes FCM. Self-image profile in children and adolescents with attention deficit/hyperactivity disorder and the quality of life in their parents. Int J Psychiatry Med (2015) 49:19–33.10.2190/PM.49.1.b
    1. van der Kolk A, Bouwmans CAM, Schawo SJ, Buitelaar JK, van Agthoven M, Hakkaart-van Roijen L. Association between quality of life and treatment response in children with attention deficit hyperactivity disorder and their parents. J Ment Health Policy Econ (2014) 17:111–21.
    1. Cruz LN, Polanczyk CA, Camey SA, Hoffmann JF, Fleck MP. Quality of life in Brazil: normative values for the Whoqol-bref in a southern general population sample. Qual Life Res (2011) 20:1123–9.10.1007/s11136-011-9845-3
    1. Fleck MP, Louzada S, Xavier M, Chachamovich E, Vieira G, Santos L, et al. [Application of the Portuguese version of the abbreviated instrument of quality life WHOQOL-bref]. Rev Saude Publica (2000) 34:178–83.10.1590/S0034-89102000000200012
    1. Mattos P, Segenreich D, Saboya E, Louzã M, Dias G, Romano M. Adaptação transcultural para o português da escala Adult Self-Report Scale para avaliação do transtorno de déficit de atenção/hiperatividade (TDAH) em adultos. Rev Psiquiatr Clin (2006) 33:188–94.10.1590/S0101-60832006000400004
    1. HAMILTON M. A rating scale for depression. J Neurol Neurosurg Psychiatry (1960) 23:56–62.10.1136/jnnp.23.1.56
    1. Gorenstein C, Andrade L, Vieira Filho AH, Tung TC, Artes R. Psychometric properties of the Portuguese version of the Beck Depression Inventory on Brazilian college students. J Clin Psychol (1999) 55:553–62.10.1002/(SICI)1097-4679(199905)55:5<553::AID-JCLP3>;2-D
    1. Wang Y-P, Andrade LH, Gorenstein C. Validation of the Beck Depression Inventory for a Portuguese-speaking Chinese community in Brazil. Braz J Med Biol Res (2005) 38:399–408.10.1590/S0100-879X2005000300011
    1. BECK AT, WARD CH, MENDELSON M, MOCK J, ERBAUGH J. An inventory for measuring depression. Arch Gen Psychiatry (1961) 4:561–71.10.1001/archpsyc.1961.01710120031004
    1. Goracci A, Fagiolini A, Martinucci M, Calossi S, Rossi S, Santomauro T, et al. Quality of life, anxiety and depression in Sarcoidosis. Anxiety (2008) 30:441–5.10.1016/j.genhosppsych.2008.04.010
    1. Dabelea D, Mayer-Davis EJ, Saydah S, Imperatore G, Linder B, Divers J, et al. Prevalence of Type 1 and Type 2 diabetes among children and adolescents from 2001 to 2009. JAMA (2014) 311:1778.10.1001/jama.2014.3201
    1. Biederman J, Faraone SV, Keenan K, Tsuang MT. Evidence of familial association between attention deficit disorder and major affective disorders. Arch Gen Psychiatry (1991) 48:633–42.10.1001/archpsyc.1991.01810310051009
    1. Gordon M, Antshel K, Faraone S, Barkley R, Lewandowski L, Hudziak JJ, et al. Symptoms versus impairment: the case for respecting DSM-IV’s Criterion D. J Atten Disord (2006) 9:465–75.10.1177/1087054705283881
    1. Latha KS, Nair RB, Bhat SM. Frequency of parental psychopathology in children with attention deficit hyperactivity disorder. Online J Heal Allied Sci (2012) 11(1):7.
    1. Lin Y-J, Lo K-W, Yang L-K, Gau SS-F. Validation of DSM-5 age-of-onset criterion of attention deficit/hyperactivity disorder (ADHD) in adults: comparison of life quality, functional impairment, and family function. Res Dev Disabil (2015) 47:48–60.10.1016/j.ridd.2015.07.026

Source: PubMed

3
Suscribir