Associations of sedentary behavior, sedentary bouts and breaks in sedentary time with cardiometabolic risk in children with a family history of obesity

Travis John Saunders, Mark Stephen Tremblay, Marie-Ève Mathieu, Mélanie Henderson, Jennifer O'Loughlin, Angelo Tremblay, Jean-Philippe Chaput, QUALITY cohort research group, Mélanie Henderson, Gilles Paradis, Jennifer O'Loughlin, Angelo Tremblay, Tracie Barnett, Jennifer McGrath, Belinda Nicolau, Travis John Saunders, Mark Stephen Tremblay, Marie-Ève Mathieu, Mélanie Henderson, Jennifer O'Loughlin, Angelo Tremblay, Jean-Philippe Chaput, QUALITY cohort research group, Mélanie Henderson, Gilles Paradis, Jennifer O'Loughlin, Angelo Tremblay, Tracie Barnett, Jennifer McGrath, Belinda Nicolau

Abstract

Background: Although reports in adults suggest that breaks in sedentary time are associated with reduced cardiometabolic risk, these findings have yet to be replicated in children.

Purpose: To investigate whether objectively measured sedentary behavior, sedentary bouts or breaks in sedentary time are independently associated with cardiometabolic risk in a cohort of Canadian children aged 8-11 years with a family history of obesity.

Methods: Data from 286 boys and 236 girls living in Quebec, Canada, with at least one biological parent with obesity (QUALITY cohort) were collected from 2005-2008, and analyzed in 2013. Sedentary behavior, light and moderate-to-vigorous physical activity were measured over 7 days using accelerometry. Leisure time computer/video game use and TV viewing over the past 7 days were self-reported. Outcomes included waist circumference, body mass index Z-score, fasting insulin, fasting glucose, triglycerides, HDL-cholesterol, C-reactive protein and a continuous cardiometabolic risk score.

Results: After adjustment for confounders, breaks in sedentary time and the number of sedentary bouts lasting 1-4 minutes were associated with reduced cardiometabolic risk score and lower BMI Z-score in both sexes (all p<0.05). The number of sedentary bouts lasting 5-9 minutes was negatively associated with waist circumference in girls only, while the number of bouts lasting 10-14 minutes was positively associated with fasting glucose in girls, and with BMI Z-score in boys (all p<0.05). Leisure time computer/video game use was associated with increased cardiometabolic risk score and waist circumference in boys, while TV viewing was associated with increased cardiometabolic risk, waist circumference, and BMI Z-score in girls (all p<0.05).

Conclusions: These results suggest that frequent interruptions in sedentary time are associated with a favourable cardiometabolic risk profile and highlight the deleterious relationship between screen time and cardiometabolic risk among children with a family history of obesity.

Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

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Source: PubMed

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