Genital pain: algorithm for management

Nahomy Calixte, Jamin Brahmbhatt, Sijo Parekattil, Nahomy Calixte, Jamin Brahmbhatt, Sijo Parekattil

Abstract

Chronic testicular pain although becoming very common in our patient population poses a challenge to the physician, the patient and his family. The pathogenesis of chronic orchialgia (CO) is not well understood. The objective of this paper is to review the current literature on chronic testicular pain and its management and to propose an algorithm for its treatment. Abstracts, original papers and review articles were reviewed during a literature search using words such as testicular pain, CO, and microsurgical anatomy of spermatic cord. Chronic scrotal content pain (CSP) is a difficult condition to treat and could be idiopathic or secondary. Conservative therapy is the first line of treatment attempted to allow the patient to return to his routine activities. When conservative treatment fails, patients can now turn toward surgical options such as microsurgical denervation of the spermatic cord (MDSC) which has a success rate published in the 60-85% range and/or minimally invasive therapies such as microcryoablation of the spermatic cord, Botox or Amniofix injection. There is an increase in referrals for CO. The true pathogenesis is still unclear and the road to complete recovery is unsure for certain patients. This paper proposes an algorithm for the management of patients suffering with CO.

Keywords: Chronic orchialgia (CO); chronic scrotal content pain (CSP); microsurgical denervation of spermatic cord; testicular pain.

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Algorithm for management of chronic orchialgia.

References

    1. Cassidy DJ. Early experience with microsurgical spermatic cord denervation for chronic orchialgia at a Canadian centre. Can Urol Assoc J 2015;9:e72-4. 10.5489/cuaj.2383
    1. Tojuola B, Layman J, Kartal I, et al. Chronic orchialgia: Review of treatments old and new. Indian J Urol 2016;32:21-6. 10.4103/0970-1591.173110
    1. Tu XA, Yu JW. Updated diagnosis and management of chronic orchialgia. Zhonghua Nan Ke Xue 2016;22:195-9.
    1. Kumar P, Mehta V, Nargund VH. Clinical management of chronic testicular pain. Urol Int 2010;84:125-31. 10.1159/000277587
    1. Levine L. Chronic orchialgia: evaluation and discussion of treatment options. Ther Adv Urol 2010;2:209-14. 10.1177/1756287210390409
    1. Parekattil SJ, Gudeloglu A, Brahmbhatt JV, et al. Trifecta nerve complex: potential anatomical basis for microsurgical denervation of the spermatic cord for chronic orchialgia. J Urol 2013;190:265-70. 10.1016/j.juro.2013.01.045
    1. Singh V, Sinha RJ. Idiopathic chronic orchialgia - a frustrating issue for the clinician and the patient. Indian J Surg 2008;70:107-10. 10.1007/s12262-008-0032-x
    1. Kavoussi PK, Costabile RA. Orchialgia and the chronic pelvic pain syndrome. World J Urol 2013;31:773-8. 10.1007/s00345-013-1092-5
    1. Masarani M, Cox R. The aetiology, pathophysiology and management of chronic orchialgia. BJU Int 2003;91:435-7. 10.1046/j.1464-410X.2003.04094.x
    1. Gordhan CG, Sadeghi-Nejad H. Scrotal pain: evaluation and management. Korean J Urol 2015;56:3-11. 10.4111/kju.2015.56.1.3
    1. Narita M, Moriyoshi K, Hanada K, et al. Successful treatment for patients with chronic orchialgia following inguinal hernia repair by means of meshoma removal, orchiectomy and triple-neurectomy. Int J Surg Case Rep 2015;16:157-61. 10.1016/j.ijscr.2015.09.044
    1. Oka S, Shiraishi K, Matsuyama H. Microsurgical anatomy of the spermatic cord and spermatic fascia: distribution of lymphatics, and sensory and autonomic nerves. J Urol 2016;195:1841-7. 10.1016/j.juro.2015.11.041
    1. Cui T, Terlecki R. Prevalence of relative deficiencies in testosterone and vitamin B12 among patients referred for chronic orchialgia: implications for management. Am J Mens Health 2016. [Epub ahead of print].
    1. Levine LA, Matkov TG, Lubenow TR. Microsurgical denervation of the spermatic cord: a surgical alternative in the treatment of chronic orchialgia. J Urol 1996;155:1005-7. 10.1016/S0022-5347(01)66369-9
    1. Levine LA, Hoeh MP. Evaluation and management of chronic scrotal content pain. Curr Urol Rep 2015;16:36. 10.1007/s11934-015-0510-1
    1. Benson JS, Abern MR, Larsen S, et al. Does a positive response to spermatic cord block predict response to microdenervation of the spermatic cord for chronic scrotal content pain? J Sex Med 2013;10:876-82. 10.1111/j.1743-6109.2012.02937.x
    1. Marconi M, Palma C, Troncoso P, et al. Microsurgical spermatic cord denervation as a treatment for chronic scrotal content pain: a multicenter open label trial. J Urol 2015;194:1323-7. 10.1016/j.juro.2015.05.081
    1. Tojuola B, Kartal I, Brahmbhatt J, et al. Targeted Robotic assisted microsurgical denervation of the spermatic cord for the treatment of chronic scrotal content pain: single center, large series review. J Urol 2015;193:e836.
    1. Calixte N, Tojuola B, Kartal I, et al. Salvage Ultrasound Guided Targeted Microcryoablation of the peri-spermatic cord for persistent Chronic Scrotal Content Pain after microsurgical denervation of the spermatic cord. Available online:
    1. Tojuola B, Kartal I, Brahmbhatt J, et al. SCROTOX: Salvage Peri-spermatic cord Botulinum-A Toxin injections for patients with refractory chronic scrotal content pain after microsurgical denervation of the spermatic cord. J Urol 2015;193:e905 10.1016/j.juro.2015.02.2581

Source: PubMed

3
Suscribir