Sleep-wake disturbances in sedentary community-dwelling elderly adults with functional limitations
Carlos A Vaz Fragoso, Michael E Miller, Roger A Fielding, Abby C King, Stephen B Kritchevsky, Mary M McDermott, Valerie Myers, Anne B Newman, Marco Pahor, Thomas M Gill, Lifestyle Interventions and Independence in Elder Study Group, Marco Pahor, Jack M Guralnik, Christiaan Leeuwenburgh, Connie Caudle, Lauren Crump, Latonia Holmes, Jocelyn Lee, Ronald Lester, Ching-ju Lu, Ryan O'Mara, Michael E Miller, Mark A Espeland, Walter T Ambrosius, William Applegate, Don Babcock, Daniel P Beavers, Robert P Byington, Delilah Cook, Curt D Furberg, Jason Griffin, Lea N Harvin, Leora Henkin, John Hepler, Fang-Chi Hsu, Laura Lovato, Wesley Roberson, Julia Rushing, Scott Rushing, Cynthia L Stowe, Michael P Walkup, Don Hire, W Jack Rejeski, Jeffrey A Katula, Peter H Brubaker, Shannon L Mihalko, Janine M Jennings, Evan C Hadley, Sergei Romashkan, Denise E Bonds, Kushang V Patel, Mary M McDermott, Bonnie Spring, Joshua Hauser, Diana Kerwin, Kathryn Domanchuk, Rex Graff, Alvito Rego, Timothy S Church, Steven N Blair, Valerie H Myers, Ron Monce, Nathan E Britt, Melissa Nauta Harris, Ami Parks McGucken, Ruben Rodarte, Heidi K Millet, Catrine Tudor-Locke, Ben P Butitta, Sheletta G Donatto, Shannon H Cocreham, Abby C King, Cynthia M Castro, William L Haskell, Randall S Stafford, Leslie A Pruitt, Kathy Berra, Veronica Yank, Roger A Fielding, Miriam E Nelson, Sara C Folta, Edward M Phillips, Christine K Liu, Erica C McDavitt, Kieran F Reid, Won S Kim, Vince E Beard, Todd M Manini, Stephen D Anton, Susan Nayfield, Thomas W Buford, Michael Marsiske, Bhanuprasad D Sandesara, Jeffrey D Knaggs, Megan S Lorow, William C Marena, Irina Korytov, Holly L Morris, Margo Fitch, Floris F Singletary, Jackie Causer, Katie A Radcliff, Anne B Newman, Stephanie A Studenski, Bret H Goodpaster, Nancy W Glynn, Oscar Lopez, Neelesh K Nadkarni, Kathy Williams, Mark A Newman, George Grove, Janet T Bonk, Jennifer Rush, Piera Kost, Diane G Ives, Stephen B Kritchevsky, Anthony P Marsh, Tina E Brinkley, Jamehl S Demons, Kaycee M Sink, Kimberly Kennedy, Rachel Shertzer-Skinner, Abbie Wrights, Rose Fries, Deborah Barr, Thomas M Gill, Robert S Axtell, Susan S Kashaf, Nathalie de Rekeneire, Joanne M McGloin, Karen C Wu, Lynne P Iannone, Raeleen Mautner, Denise M Shepard, Barbara Fennelly, Theresa Sweeney Barnett, Sean N Halpin, Matthew J Brennan, Julie A Bugaj, Maria A Zenoni, Bridget M Mignosa, Jeff Williamson, Kaycee M Sink, Hugh C Hendrie, Stephen R Rapp, Joe Verghese, Nancy Woolard, Mark Espeland, Janine Jennings, Carl J Pepine, Mario Ariet, Eileen Handberg, Daniel Deluca, James Hill, Anita Szady, Geoffrey L Chupp, Gail M Flynn, Thomas M Gill, John L Hankinson, Carlos A VazFragoso, Erik J Groessl, Robert M Kaplan, Carlos A Vaz Fragoso, Michael E Miller, Roger A Fielding, Abby C King, Stephen B Kritchevsky, Mary M McDermott, Valerie Myers, Anne B Newman, Marco Pahor, Thomas M Gill, Lifestyle Interventions and Independence in Elder Study Group, Marco Pahor, Jack M Guralnik, Christiaan Leeuwenburgh, Connie Caudle, Lauren Crump, Latonia Holmes, Jocelyn Lee, Ronald Lester, Ching-ju Lu, Ryan O'Mara, Michael E Miller, Mark A Espeland, Walter T Ambrosius, William Applegate, Don Babcock, Daniel P Beavers, Robert P Byington, Delilah Cook, Curt D Furberg, Jason Griffin, Lea N Harvin, Leora Henkin, John Hepler, Fang-Chi Hsu, Laura Lovato, Wesley Roberson, Julia Rushing, Scott Rushing, Cynthia L Stowe, Michael P Walkup, Don Hire, W Jack Rejeski, Jeffrey A Katula, Peter H Brubaker, Shannon L Mihalko, Janine M Jennings, Evan C Hadley, Sergei Romashkan, Denise E Bonds, Kushang V Patel, Mary M McDermott, Bonnie Spring, Joshua Hauser, Diana Kerwin, Kathryn Domanchuk, Rex Graff, Alvito Rego, Timothy S Church, Steven N Blair, Valerie H Myers, Ron Monce, Nathan E Britt, Melissa Nauta Harris, Ami Parks McGucken, Ruben Rodarte, Heidi K Millet, Catrine Tudor-Locke, Ben P Butitta, Sheletta G Donatto, Shannon H Cocreham, Abby C King, Cynthia M Castro, William L Haskell, Randall S Stafford, Leslie A Pruitt, Kathy Berra, Veronica Yank, Roger A Fielding, Miriam E Nelson, Sara C Folta, Edward M Phillips, Christine K Liu, Erica C McDavitt, Kieran F Reid, Won S Kim, Vince E Beard, Todd M Manini, Stephen D Anton, Susan Nayfield, Thomas W Buford, Michael Marsiske, Bhanuprasad D Sandesara, Jeffrey D Knaggs, Megan S Lorow, William C Marena, Irina Korytov, Holly L Morris, Margo Fitch, Floris F Singletary, Jackie Causer, Katie A Radcliff, Anne B Newman, Stephanie A Studenski, Bret H Goodpaster, Nancy W Glynn, Oscar Lopez, Neelesh K Nadkarni, Kathy Williams, Mark A Newman, George Grove, Janet T Bonk, Jennifer Rush, Piera Kost, Diane G Ives, Stephen B Kritchevsky, Anthony P Marsh, Tina E Brinkley, Jamehl S Demons, Kaycee M Sink, Kimberly Kennedy, Rachel Shertzer-Skinner, Abbie Wrights, Rose Fries, Deborah Barr, Thomas M Gill, Robert S Axtell, Susan S Kashaf, Nathalie de Rekeneire, Joanne M McGloin, Karen C Wu, Lynne P Iannone, Raeleen Mautner, Denise M Shepard, Barbara Fennelly, Theresa Sweeney Barnett, Sean N Halpin, Matthew J Brennan, Julie A Bugaj, Maria A Zenoni, Bridget M Mignosa, Jeff Williamson, Kaycee M Sink, Hugh C Hendrie, Stephen R Rapp, Joe Verghese, Nancy Woolard, Mark Espeland, Janine Jennings, Carl J Pepine, Mario Ariet, Eileen Handberg, Daniel Deluca, James Hill, Anita Szady, Geoffrey L Chupp, Gail M Flynn, Thomas M Gill, John L Hankinson, Carlos A VazFragoso, Erik J Groessl, Robert M Kaplan
Abstract
Objectives: To evaluate sleep-wake disturbances in sedentary community-dwelling elderly adults with functional limitations.
Design: Cross-sectional.
Setting: Lifestyle Interventions and Independence in Elder (LIFE) Study.
Participants: Community-dwelling persons (mean age 78.9) who spent fewer than 20 min/wk in the previous month engaged in regular physical activity and fewer than 125 min/wk of moderate physical activity, and had a Short Physical Performance Battery (SPPB) score of <10 (N = 1,635).
Measurements: Mobility was evaluated according to 400-m walk time (slow gait speed defined as <0.8 m/s) and SPPB score (≤ 7 defined moderate to severe mobility impairment). Physical inactivity was defined according to sedentary time, as a percentage of accelerometry wear time with activity of <100 counts/min; participants in the top quartile of sedentary time were classified as having a high sedentary time. Sleep-wake disturbances were evaluated using the Insomnia Severity Index (ISI) (range 0-28; ≥ 8 defined insomnia), Epworth Sleepiness Scale (ESS) (range 0-24; ≥ 10 defined daytime drowsiness), Pittsburgh Sleep Quality Index (PSQI) (range 0-21; >5 defined poor sleep quality), and Berlin Questionnaire (high risk of sleep apnea).
Results: Prevalence rates were 43.5% for slow gait speed and 44.7% for moderate to severe mobility impairment, with 77.0% of accelerometry wear time spent as sedentary time. Prevalence rates were 33.0% for insomnia, 18.1% for daytime drowsiness, 47.8% for poor sleep quality, and 32.9% for high risk of sleep apnea. Participants with insomnia had a mean ISI score of 12.1, those with daytime drowsiness had a mean ESS score of 12.5, and those with poor sleep quality had a mean PSQI score of 9.2. In adjusted models, measures of mobility and physical inactivity were generally not associated with sleep-wake disturbances, using continuous or categorical variables.
Conclusion: In a large sample of sedentary community-dwelling elderly adults with functional limitations, sleep-wake disturbances were prevalent but only mildly severe and were generally not associated with mobility impairment or physical inactivity.
Trial registration: ClinicalTrials.gov NCT01072500.
Keywords: mobility impairment; physical inactivity; sleep-wake disturbances.
Conflict of interest statement
Conflict of Interest: The editor in chief has reviewed the conflict of interest checklist provided by the authors and has determined that the authors have no financial or any other kind of personal conflicts with this paper.
© 2014, Copyright the Authors Journal compilation © 2014, The American Geriatrics Society.
Source: PubMed