Adapting a Motivational Interviewing Intervention to Improve HIV Prevention Among Young, Black, Sexual Minority Men in Alabama: Protocol for the Development of the Kings Digital Health Intervention

Henna Budhwani, B Matthew Kiszla, Angulique Y Outlaw, Robert A Oster, Michael J Mugavero, Mallory O Johnson, Lisa B Hightow-Weidman, Sylvie Naar, Janet M Turan, Henna Budhwani, B Matthew Kiszla, Angulique Y Outlaw, Robert A Oster, Michael J Mugavero, Mallory O Johnson, Lisa B Hightow-Weidman, Sylvie Naar, Janet M Turan

Abstract

Background: African American or Black young men who have sex with men (BYMSM) are at a disproportionate risk for contracting HIV and have high rates of undiagnosed, and therefore untreated, HIV infection. In the southern United States, BYMSM face region-specific hurdles to HIV prevention, such as limited access to care and high levels of racism and intersectional stigma, necessitating HIV testing and pre-exposure prophylaxis interventions that address sociocultural and structural barriers while motivating BYMSM to engage in prevention. Brothers Saving Brothers (BSB) is a motivational interviewing behavioral intervention that successfully and simultaneously increased community-based HIV testing and prevention counseling and education among BYMSM in the midwestern United States.

Objective: The aim of this protocol is to detail the process for the adaption of the BSB intervention for midwestern BYMSM to the Kings intervention for southern BYMSM. During the adaptation process, the intervention will be modernized to include rapid HIV testing, as opposed to HIV testing that requires BYMSM to return for test results, pre-exposure prophylaxis, and the provision of structural supports, and for relevance in the southern United States.

Methods: Aim 1 is to gather qualitative data through focus groups and in-depth interviews with BYMSM aged 18 to 29 years in Alabama and in-depth interviews with prevention and outreach workers who routinely work with BYMSM in Alabama. NVivo qualitative software (QSR International) will be used for the coding and analysis of the transcripts via a thematic analysis approach. For aim 2, intervention mapping will guide the adaptation process, intervention content, components, and design. Both aims 1 and 2 will leverage the Exploration, Preparation, Implementation, Sustainment implementation science framework, with emphasis on the exploration and preparation phases of this model. By applying these frameworks, the original midwestern BSB intervention will be scientifically adapted to the southern BYMSM Kings intervention.

Results: This study is ongoing as of 2022 and is expected to conclude in 2024, with aims 1 and 2 being completed in 2023. Qualitative data will offer insight into the current real-world experiences and preferences of BYMSM in Alabama. Feedback will be collected through the adaptation process to inform intervention refinement. Institutional review board approvals have been received.

Conclusions: The findings will inform next steps, that is, testing the Kings intervention for feasibility, acceptability, and preliminary effectiveness in a pilot hybrid type 1 effective-implementation randomized controlled trial. The study results will provide insights about important considerations for HIV prevention among BYMSM in the southern United States.

Trial registration: ClinicalTrials.gov NCT03680729; https://ichgcp.net/clinical-trials-registry/NCT03680729.

International registered report identifier (irrid): PRR1-10.2196/36655.

Keywords: African American; Alabama; HIV; implementation science; intervention; men who have sex with men; pre-exposure prophylaxis; sociocultural; structural barriers; youth.

Conflict of interest statement

Conflicts of Interest: None declared.

©Henna Budhwani, B Matthew Kiszla, Angulique Y Outlaw, Robert A Oster, Michael J Mugavero, Mallory O Johnson, Lisa B Hightow-Weidman, Sylvie Naar, Janet M Turan. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 13.07.2022.

Figures

Figure 1
Figure 1
Intervention mapping framework for adapting the Brothers Saving Brothers intervention to the Kings intervention. PrEP: pre-exposure prophylaxis.

References

    1. CDC fact sheet: HIV among gay and bisexual men. Centers for Disease Control and Prevention. [2019-03-01]. .
    1. Aghaizu A, Nardone A, Copas A, Mercey D, Wayal S, Parsons V, Hart G, Gilson R, Johnson A. O5 Understanding continuing high hiv incidence: sexual behavioural trends among msm in london, 2000–2013. Sex Transm Infect. 2015 May 18;91(Suppl 1):A2. doi: 10.1136/sextrans-2015-052126.5.
    1. Centers for Disease Control and Prevention (CDC) Vital signs: HIV infection, testing, and risk behaviors among youths - United States. MMWR Morb Mortal Wkly Rep. 2012 Nov 30;61(47):971–976. mm6147a5
    1. Hall HI, An Q, Tang T, Song R, Chen M, Green T, Kang J, Centers for Disease Control and Prevention (CDC) Prevalence of diagnosed and undiagnosed HIV infection--United States, 2008-2012. MMWR Morb Mortal Wkly Rep. 2015 Jun 26;64(24):657–662. mm6424a2
    1. State of Alabama HIV surveillance 2014 annual report. Alabama Department of Public Health. 2016. [2019-03-01]. .
    1. Johnson AS, Hall HI, Hu X, Lansky A, Holtgrave DR, Mermin J. Trends in diagnoses of HIV infection in the United States, 2002-2011. JAMA. 2014 Jul;312(4):432–434. doi: 10.1001/jama.2014.8534. 1889120
    1. Han CS, Ayala G, Paul JP, Boylan R, Gregorich SE, Choi KH. Stress and coping with racism and their role in sexual risk for HIV among African American, Asian/Pacific Islander, and Latino men who have sex with men. Arch Sex Behav. 2015 Feb;44(2):411–420. doi: 10.1007/s10508-014-0331-1.
    1. Konkle-Parker DJ, Erlen JA, Dubbert PM. Lessons learned from an HIV adherence pilot study in the Deep South. Patient Educ Couns. 2010 Jan;78(1):91–96. doi: 10.1016/j.pec.2009.04.010. S0738-3991(09)00238-9
    1. Prejean J, Tang T, Hall HI. HIV diagnoses and prevalence in the southern region of the United States, 2007-2010. J Community Health. 2013 Jun;38(3):414–426. doi: 10.1007/s10900-012-9633-1.
    1. LGBT data and demographics. The Williams Institute. [2019-04-17]. .
    1. Alabama 2012-2016 statewide jurisdictional HIV prevention plan. Alabama Department of Public Health. [2019-04-17]. .
    1. Peirce NR. The Deep South States of America: People, Politics, and Power in the Seven Deep South States. New York, NY: W.W. Norton & Company; 1974.
    1. Amico KR, Konkle-Parker DJ, Cornman DH, Barta WD, Ferrer R, Norton WE, Trayling C, Shuper P, Fisher JD, Fisher WA. Reasons for ART non-adherence in the Deep South: adherence needs of a sample of HIV-positive patients in Mississippi. AIDS Care. 2007 Nov;19(10):1210–1218. doi: 10.1080/09540120701426516. 788286015
    1. Garofalo R, Mustanski B, Johnson A, Emerson E. Exploring factors that underlie racial/ethnic disparities in HIV risk among young men who have sex with men. J Urban Health. 2010 Mar;87(2):318–323. doi: 10.1007/s11524-009-9430-z. 10.1007/s11524-009-9430-z
    1. Reif S, Mugavero M, Raper J, Thielman N, Leserman J, Whetten K, Pence BW. Highly stressed: stressful and traumatic experiences among individuals with HIV/AIDS in the Deep South. AIDS Care. 2011 Feb;23(2):152–162. doi: 10.1080/09540121.2010.498872. 932648837
    1. Doshi RK, Malebranche D, Bowleg L, Sangaramoorthy T. Health care and HIV testing experiences among Black men in the South: implications for "Seek, Test, Treat, and Retain" HIV prevention strategies. AIDS Patient Care STDS. 2013 Feb;27(2):123–133. doi: 10.1089/apc.2012.0269.
    1. Eaton LA, Driffin DD, Kegler C, Smith H, Conway-Washington C, White D, Cherry C. The role of stigma and medical mistrust in the routine health care engagement of black men who have sex with men. Am J Public Health. 2015 Feb;105(2):e75–e82. doi: 10.2105/AJPH.2014.302322.
    1. Irvin R, Wilton L, Scott H, Beauchamp G, Wang L, Betancourt J, Lubensky M, Wallace J, Buchbinder S. A study of perceived racial discrimination in Black men who have sex with men (MSM) and its association with healthcare utilization and HIV testing. AIDS Behav. 2014 Jul;18(7):1272–1278. doi: 10.1007/s10461-014-0734-y.
    1. Santos GM, Beck J, Wilson PA, Hebert P, Makofane K, Pyun T, Do T, Arreola S, Ayala G. Homophobia as a barrier to HIV prevention service access for young men who have sex with men. J Acquir Immune Defic Syndr. 2013 Aug 15;63(5):e167–e170. doi: 10.1097/QAI.0b013e318294de80.00126334-201308150-00024
    1. Skarbinski J, Rosenberg E, Paz-Bailey G, Hall HI, Rose CE, Viall AH, Fagan JL, Lansky A, Mermin JH. Human immunodeficiency virus transmission at each step of the care continuum in the United States. JAMA Intern Med. 2015 Apr;175(4):588–596. doi: 10.1001/jamainternmed.2014.8180.2130723
    1. Levy ME, Wilton L, Phillips G 2nd, Glick SN, Kuo I, Brewer RA, Elliott A, Watson C, Magnus M. Understanding structural barriers to accessing HIV testing and prevention services among black men who have sex with men (BMSM) in the United States. AIDS Behav. 2014 May;18(5):972–996. doi: 10.1007/s10461-014-0719-x.
    1. Budhwani H, De P, Sun R. Perceived stigma in health care settings mediates the relationships between depression, diabetes, and hypertension. Popul Health Manag. 2022 Apr;25(2):164–171. doi: 10.1089/pop.2021.0268.
    1. Budhwani H, Yigit I, Ofotokun I, Konkle-Parker DJ, Cohen MH, Wingood GM, Metsch LR, Adimora AA, Taylor TN, Wilson TE, Weiser SD, Kempf MC, Sosanya O, Gange S, Kassaye S, Turan B, Turan JM. Examining the relationships between experienced and anticipated stigma in health care settings, patient-provider race concordance, and trust in providers among women living with HIV. AIDS Patient Care STDS. 2021 Nov;35(11):441–448. doi: 10.1089/apc.2021.0096.
    1. Outlaw AY, Naar-King S, Parsons JT, Green-Jones M, Janisse H, Secord E. Using motivational interviewing in HIV field outreach with young African American men who have sex with men: a randomized clinical trial. Am J Public Health. 2010 Apr 01;100 Suppl 1(Suppl 1):S146–S151. doi: 10.2105/AJPH.2009.166991.AJPH.2009.166991
    1. Konkle-Parker DJ, Erlen JA, Dubbert PM. Barriers and facilitators to medication adherence in a southern minority population with HIV disease. J Assoc Nurses AIDS Care. 2008;19(2):98–104. doi: 10.1016/j.jana.2007.09.005. S1055-3290(08)00007-1
    1. Amico KR. Developing an “HIV Prevention Cascade”: Current approach and future directions. International Association of Providers of AIDS Care; 10th International Conference on HIV Treatment and Prevention Adherence (IAPAC); June 28-30, 2015; Miami, FL. 2015. Jun 30,
    1. Fisher WA, Fisher JD. A general social psychological model for changing AIDS risk behavior. In: Pryor JB, Reeder GD, editors. The Social Psychology of HIV Infection. London, England: Psychology Press; 2017. pp. 27–53.
    1. Fisher WA, Fisher JD. Understanding and promoting sexual and reproductive health behavior: theory and method. Annu Rev Sex Res. 1998;9:39–76.
    1. Fisher WA, Fisher JD, Harman J. The Information–Motivation–Behavioral Skills Model: A general social psychological approach to understanding and promoting health behavior. In: Suls J, Wallston KA, editors. Social Psychological Foundations of Health and Illness. Hoboken, NJ: Blackwell Publishing Ltd; 2003. pp. 82–106.
    1. Hochbaum GM. Public Participation in Medical Screening Programs: A Sociopsychological Study. Washington, DC: US Government Printing Office; 1958.
    1. Bandura A. Perceived self-efficacy in the exercise of control over AIDS infection. Eval Program Plann. 1990;13(1):9–17. doi: 10.1016/0149-7189(90)90004-g.
    1. Aarons GA, Hurlburt M, Horwitz SM. Advancing a conceptual model of evidence-based practice implementation in public service sectors. Adm Policy Ment Health. 2011 Jan;38(1):4–23. doi: 10.1007/s10488-010-0327-7.
    1. Brownson RC, Colditz GA, Proctor EK. Dissemination and Implementation Research in Health: Translating Science to Practice. New York, NY: Oxford University Press; 2012.
    1. Glisson C, Landsverk J, Schoenwald S, Kelleher K, Hoagwood KE, Mayberg S, Green P, Research Network on Youth Mental Health Assessing the organizational social context (OSC) of mental health services: implications for research and practice. Adm Policy Ment Health. 2008 Mar;35(1-2):98–113. doi: 10.1007/s10488-007-0148-5.
    1. Curran GM, Bauer M, Mittman B, Pyne JM, Stetler C. Effectiveness-implementation hybrid designs: combining elements of clinical effectiveness and implementation research to enhance public health impact. Med Care. 2012 Mar;50(3):217–226. doi: 10.1097/MLR.0b013e3182408812.
    1. Sullivan P, Goldmann D. The promise of comparative effectiveness research. JAMA. 2011 Jan 26;305(4):400–401. doi: 10.1001/jama.2011.12.305/4/400
    1. Rollnick S, Miller WR, Butler CC. Motivational Interviewing in Health Care: Helping Patients Change Behavior. New York, NY: Guilford Press; 2008.
    1. Miller WR, Rollnick S. Meeting in the middle: motivational interviewing and self-determination theory. Int J Behav Nutr Phys Act. 2012 Mar 02;9:25. doi: 10.1186/1479-5868-9-25. 1479-5868-9-25
    1. Budhwani H, Robles G, Starks TJ, MacDonell KK, Dinaj V, Naar S. Healthy Choices intervention is associated with reductions in stigma among youth living with HIV in the United States (ATN 129) AIDS Behav. 2021 Apr;25(4):1094–1102. doi: 10.1007/s10461-020-03071-1. 10.1007/s10461-020-03071-1
    1. Budhwani H, Naar S. Training providers in Motivational Interviewing to promote behavior change. Pediatr Clin North Am (forthcoming) 2022
    1. Miller WR, Rollnick S. Motivational Interviewing: Helping People Change, 3rd Edition. New York, NY: Guilford Press; 2013.
    1. Ashman JJ, Conviser R, Pounds MB. Associations between HIV-positive individuals' receipt of ancillary services and medical care receipt and retention. AIDS Care. 2002 Aug;14 Suppl 1:S109–S118. doi: 10.1080/09540120220149993a.
    1. Parsons JT, Lelutiu-Weinberger C, Botsko M, Golub SA. A randomized controlled trial utilizing motivational interviewing to reduce HIV risk and drug use in young gay and bisexual men. J Consult Clin Psychol. 2014 Feb;82(1):9–18. doi: 10.1037/a0035311. 2013-44753-001
    1. Burke BL, Arkowitz H, Menchola M. The efficacy of motivational interviewing: a meta-analysis of controlled clinical trials. J Consult Clin Psychol. 2003 Oct;71(5):843–861. doi: 10.1037/0022-006X.71.5.843.2003-07816-001
    1. Naar S, Suarez M. Motivational Interviewing with Adolescents and Young Adults. New York, NY: Guilford Press; 2021.
    1. Fundamentals of motivational interviewing for HIV. Centers for Disease Control and Prevention. [2021-12-23]. .
    1. Magic City Wellness Center. Magic City Wellness Center. [2022-01-12].
    1. Medical advocacy and outreach. Medical Advocacy and Outreach. [2022-01-12].
    1. Arnett JJ. Emerging Adulthood: The Winding Road from the Late Teens through the Twenties. New York, NY: Oxford University Press, Inc; 2004.
    1. Arnett JJ. Afterword: Aging out of care--toward realizing the possibilities of emerging adulthood. New Dir Youth Dev. 2007;(113):151–161. doi: 10.1002/yd.207.
    1. Fixsen DL, Naoom SF, Blase KA, Friedman RM, Wallace F. Implementation research: A synthesis of the literature. National Implementation Research Network. 2005. Jan, [2022-06-28]. .
    1. Parsons ML, Cornett PA. Leading change for sustainability. Nurse Lead. 2011 Aug 01;9(4):36–40. doi: 10.1016/j.mnl.2011.05.005.
    1. Meyers DC, Durlak JA, Wandersman A. The quality implementation framework: a synthesis of critical steps in the implementation process. Am J Community Psychol. 2012 Dec;50(3-4):462–480. doi: 10.1007/s10464-012-9522-x.
    1. Glisson C. Assessing and changing organizational culture and climate for effective services. Res Soc Work Pract. 2007 Nov 01;17(6):736–747. doi: 10.1177/1049731507301659.
    1. Attride-Stirling J. Thematic networks: an analytic tool for qualitative research. Qual Res. 2001 Dec 01;1(3):385–405. doi: 10.1177/146879410100100307.
    1. Strauss A, Corbin J. Basics of Qualitative Research: Techniques and Procedures for Developing Grounded Theory, Second Edition. Thousand Oaks, CA: Sage Publications; 1998.
    1. Merlin JS, Young SR, Johnson MO, Saag M, Demonte W, Kerns R, Bair MJ, Kertesz S, Turan JM, Kilgore M, Clay OJ, Pekmezi D, Davies S. Intervention mapping to develop a Social Cognitive Theory-based intervention for chronic pain tailored to individuals with HIV. Contemp Clin Trials Commun. 2018 Feb 19;10:9–16. doi: 10.1016/j.conctc.2018.02.004.S2451-8654(17)30183-7
    1. Budhwani H, Kiszla BM, Hightow-Weidman LB. Adapting digital health interventions for the evolving HIV landscape: examples to support prevention and treatment research. Curr Opin HIV AIDS. 2022 Mar 01;17(2):112–118. doi: 10.1097/COH.0000000000000721.01222929-202203000-00011
    1. Shingleton RM, Palfai TP. Technology-delivered adaptations of motivational interviewing for health-related behaviors: A systematic review of the current research. Patient Educ Couns. 2016 Jan;99(1):17–35. doi: 10.1016/j.pec.2015.08.005. S0738-3991(15)30043-4

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