Imaging the upper gastrointestinal tract in unsedated patients using tethered capsule endomicroscopy

Michalina J Gora, Jenny S Sauk, Robert W Carruth, Weina Lu, Drew T Carlton, Amna Soomro, Mireille Rosenberg, Norman S Nishioka, Guillermo J Tearney, Michalina J Gora, Jenny S Sauk, Robert W Carruth, Weina Lu, Drew T Carlton, Amna Soomro, Mireille Rosenberg, Norman S Nishioka, Guillermo J Tearney

No abstract available

Keywords: BE; Barrett's esophagus; GI; NPO; OFDI; gastrointestinal; non per os; optical frequency domain imaging.

Conflict of interest statement

Competing financial interests

G.J.T. receives sponsored research funding from Ninepoint Medical. G.J.T. and N.S.N. are consultants for Ninepoint Medical. G.J.T. and N.S.N. have the rights to receive royalties under a licensing arrangement between Massachusetts General Hospital and Ninepoint Medical. The remaining authors disclose no conflicts.

Figures

Figure 1

Photograph of the whole tethered capsule endomicroscopy catheter with the capsule adjacent to a penny for scale.

Figure 2

Tethered capsule endomicroscopy images obtained from a healthy volunteer in vivo showing (a) the architectural morphology of the normal esophageal wall, including the squamous epithelium (E), muscularis mucosa (MM), lamina propria (L), submucosa (S), inner muscularis (IM), outer muscularis (OM) and myenteric plexus (MP) and (b) the stomach with characteristic glandular ‘pits’ (arrowheads). The blue asterisk indicates a multiple reflection artifact. Tick marks 1 mm; scale bars 0.5 mm.