Coagulation dynamics of a blood sample by multiple scattering analysis
Magalie Faivre, Philippe Peltié, Anne Planat-Chrétien, Marie-Line Cosnier, Myriam Cubizolles, Christophe Nougier, Claude Négrier, Patrick Pouteau, Magalie Faivre, Philippe Peltié, Anne Planat-Chrétien, Marie-Line Cosnier, Myriam Cubizolles, Christophe Nougier, Claude Négrier, Patrick Pouteau
Abstract
We report a new technique to measure coagulation dynamics on whole-blood samples. The method relies on the analysis of the speckle figure resulting from a whole-blood sample mixed with coagulation reagent and introduced in a thin chamber illuminated with a coherent light. A dynamic study of the speckle reveals a typical behavior due to coagulation. We compare our measured coagulation times to a reference method obtained in a medical laboratory.
Source: PubMed