A Randomized Controlled Trial of a Behavioral Weight Loss Program for Human Immunodeficiency Virus-Infected Patients

Abstract

Obesity compounds the negative health effects of human immunodeficiency virus (HIV) infection. We conducted the first randomized trial of behavioral weight loss for HIV-infected patients (n = 40). Participants randomized to an Internet behavioral weight loss program had greater 12-week weight loss (mean, 4.4 ± 5.4 kg vs 1.0 ± 3.3 kg; P = .02) and improvements in quality of life than controls. Clinical Trials Registration NCT02421406.

Keywords: HIV; adherence; quality of life; weight loss.

© The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Figures

Figure 1.

Percentage of body weight loss over the 12-week trial in the Internet-delivered behavioral weight loss (WTLOSS; blue) and Internet-delivered education (CONTROL; red) groups using intent-to-treat analysis. A, Group means (standard error [SE]). B, Individual participants.