Multilocus sequence types of carbapenem-resistant Pseudomonas aeruginosa in Singapore carrying metallo-beta-lactamase genes, including the novel bla(IMP-26) gene
Tse Hsien Koh, Cheng Teng Khoo, Thuan Tong Tan, Mohamed Amir Bin Mohamed Arshad, Li Ping Ang, Lee Jin Lau, Li-Yang Hsu, Eng Eong Ooi, Tse Hsien Koh, Cheng Teng Khoo, Thuan Tong Tan, Mohamed Amir Bin Mohamed Arshad, Li Ping Ang, Lee Jin Lau, Li-Yang Hsu, Eng Eong Ooi
Abstract
Nine imipenem-resistant Pseudomonas aeruginosa isolates were found to contain a variety of metallo-beta-lactamase genes, including bla(IMP-1), bla(IMP-7), bla(VIM-2), bla(VIM-6), and the novel bla(IMP-26). Multilocus sequence typing showed a diversity of sequence types. Comparison with isolates from an earlier study showed that the epidemic clones from 2000 have not become established.
Figures
Dendrogram of PFGE patterns of P. aeruginosa isolates with metallo-β-lactamase genes, showing the year of isolation, MLST sequence type, and BURST group.
Source: PubMed