Guidance for identification and treatment of individuals with attention deficit/hyperactivity disorder and autism spectrum disorder based upon expert consensus

Susan Young, Jack Hollingdale, Michael Absoud, Patrick Bolton, Polly Branney, William Colley, Emily Craze, Mayuri Dave, Quinton Deeley, Emad Farrag, Gisli Gudjonsson, Peter Hill, Ho-Lan Liang, Clodagh Murphy, Peri Mackintosh, Marianna Murin, Fintan O'Regan, Dennis Ougrin, Patricia Rios, Nancy Stover, Eric Taylor, Emma Woodhouse, Susan Young, Jack Hollingdale, Michael Absoud, Patrick Bolton, Polly Branney, William Colley, Emily Craze, Mayuri Dave, Quinton Deeley, Emad Farrag, Gisli Gudjonsson, Peter Hill, Ho-Lan Liang, Clodagh Murphy, Peri Mackintosh, Marianna Murin, Fintan O'Regan, Dennis Ougrin, Patricia Rios, Nancy Stover, Eric Taylor, Emma Woodhouse

Abstract

Background: Individuals with co-occurring hyperactivity disorder/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) can have complex presentations that may complicate diagnosis and treatment. There are established guidelines with regard to the identification and treatment of ADHD and ASD as independent conditions. However, ADHD and ASD were not formally recognised diagnostically as co-occurring conditions until the Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5) was published in 2013. Hence, awareness and understanding of both conditions when they co-occur is less established and there is little guidance in the clinical literature. This has led to uncertainty among healthcare practitioners when working with children, young people and adults who present with co-existing ADHD and ASD. The United Kingdom ADHD Partnership (UKAP) therefore convened a meeting of professional experts that aimed to address this gap and reach expert consensus on the topic that will aid healthcare practitioners and allied professionals when working with this complex and vulnerable population.

Method: UK experts from multiple disciplines in the fields of ADHD and ASD convened in London in December 2017. The meeting provided the opportunity to address the complexities of ADHD and ASD as a co-occurring presentation from different perspectives and included presentations, discussion and group work. The authors considered the clinical challenges of working with this complex group of individuals, producing a consensus for a unified approach when working with male and female, children, adolescents and adults with co-occurring ADHD and ASD. This was written up, circulated and endorsed by all authors.

Results: The authors reached a consensus of practical recommendations for working across the lifespan with males and females with ADHD and ASD. Consensus was reached on topics of (1) identification and assessment using rating scales, clinical diagnostic interviews and objective supporting assessments; outcomes of assessment, including standards of clinical reporting; (2) non-pharmacological interventions and care management, including psychoeducation, carer interventions/carer training, behavioural/environmental and Cognitive Behavioural Therapy (CBT) approaches; and multi-agency liaison, including educational interventions, career advice, occupational skills and training, and (3) pharmacological treatments.

Conclusions: The guidance and practice recommendations (Tables 1, 4, 5, 7, 8 and 10) will support healthcare practitioners and allied professionals to meet the needs of this complex group from a multidisciplinary perspective. Further research is needed to enhance our understanding of the diagnosis, treatment and management of individuals presenting with comorbid ADHD and ASD.

Keywords: Assessment; Autism spectrum disorder (ASD); Comorbidity; Consensus; Education; Guidance; Interventions; Occupation; Psychiatry; Psychology; School; Treatment; hyperactivity disorder/hyperactivity disorder (ADHD).

Conflict of interest statement

In the last 5 years, SY has received honoraria for consultancy and educational talks years from Janssen, HB Pharma and/or Shire. She is an author of the RATE Scales [70]; the Diagnostic Autism Spectrum Interview (DASI) [78]; the ADHD Child Evaluation (ACE) [82] and ACE+ for adults [83]; Helping Children with ADHD CBT programme [101]; The Star Programme for children with cognitive, behavioural, emotional and social problems [102, 103]; and R&R2 for ADHD Youths and Adults [113]. PH has received honoraria for consultancy and educational talks in the last 5 years from Shire, Janssen and Flynn. He has acted as an expert witness for Lilly. PB has received honoraria for educational talks from Shire and research grants from Action Medical Research and the UK Tuberous Sclerosis Association for research on ASD and ADHD. In addition, SY, PB, WC, PH, FOR, PR, NS and EW are affiliated on a full-time basis with consultancy firms/private practices. The remaining authors have no disclosures.

References

    1. Polanczyk G, De Lima MS, Horta BL, Biederman J, Rohde LA. The worldwide prevalence of ADHD: a systematic review and metaregression analysis. Am J Psychiatry. 2007;164(6):942–948.
    1. Thapar A, Cooper M. Attention deficit hyperactivity disorder. Lancet. 2016;387(10024):1240–1250. doi: 10.1016/S0140-6736(15)00238-X.
    1. Hollingdale J, Woodhouse E, Young S, Fridman A, Mandy W. Autistic spectrum disorder symptoms in children and adolescents with attention deficit/hyperactivity disorder: a meta-analytical review. Psychol Med, BMC Psychiatry. 19:404. 10.1186/s12888-019-2284-3.
    1. Diagnostic and statistical manual of mental disorders. 5th ed (DSM-5). Arlington, VA: American Psychiatric Association. 2013.
    1. Spencer TJ, Biederman J, Mick E. Attention-deficit/hyperactivity disorder: diagnosis, lifespan, comorbidities, and neurobiology. J Pediatr Psychol. 2007;32(6):631–642.
    1. Thomas R., Sanders S., Doust J., Beller E., Glasziou P. Prevalence of Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-analysis. PEDIATRICS. 2015;135(4):e994–e1001.
    1. Simon V, Czobor P, Bálint S, Mészáros A, Bitter I. Prevalence and correlates of adult attention-deficit hyperactivity disorder: meta-analysis. Br J Psychiatry. 2009;194(3):204–211. doi: 10.1192/bjp.bp.107.048827.
    1. Michielsen M, Semeijn E, Comijs HC, Van de Ven P, Beekman TF, Deeq DJH, et al. Prevalence of attention-deficit hyperactivity disorder in older adults in the Netherlands. Br J Psychiatry. 2012;201(4):298–305.
    1. Faraone SV, Biederman J, Mick E. The age-dependent decline of attention deficit hyperactivity disorder: a meta-analysis of follow-up studies. Psychol Med. 2006;36(2):159–165.
    1. Weiss G, Hechtman LT. Hyperactive children grown up: ADHD in children, adolescents, and adults. 2nd ed. New York: Guilford Press; 1993.
    1. World Health Organization. (2016). International classification of diseases 11th ed (ICD-11).. Accessed 21 Apr 2019.
    1. Diagnostic and statistical manual of mental disorders, text revision. 4th ed (DSM-IV). Washington, DC: American Psychiatric Association. 2000.
    1. World Health Organization. (2018). International classification of diseases 11th ed (ICD-11). Update. . Accessed 21 Apr 2019.
    1. Kooij JJS, Bijlenga D, Salerno L, Jaeschke R, Bitter I, Balázs J, et al. Updated European consensus statement on diagnosis and treatment of adult ADHD. Eur Psychiatry. 2019;56:14–34.
    1. Jensen CM, Steinhausen HC. Comorbid mental disorders in children and adolescents with attention-deficit/hyperactivity disorder in a large nationwide study. Atten Defic Hyperact Disord. 2015;7(1):27–38.
    1. Spencer T, Biederman J, Wilens T. Attention-deficit/hyperactivity disorder and comorbidity. Pediatr Clin N Am. 1999;46(5):915–927.
    1. Pliszka SR, Carlson CL, Swanson JM. ADHD with comorbid disorders: clinical assessment and management. New York: Guilford Press; 1999.
    1. Mancini C, Van Ameringen M, Oakman JM, Figueiredo D. Childhood attention deficit/hyperactivity disorder in adults with anxiety disorders. Psychol Med. 1999;29(3):515–525.
    1. Kessler RC, Adler L, Barkley R, Biederman J, Conners CK, Demler O, et al. The prevalence and correlates of adult ADHD in the United States: results from the National Comorbidity Survey Replication. Am J Psychiatry. 2006;163(4):716–723.
    1. Fayyad J, Sampson NA, Hwang I, Adamowski T, Aquilar-Gaxiola S, Al-Hamzawi A, et al. The descriptive epidemiology of DSM-IV adult ADHD in the World Health Organization World Mental Health Surveys. Atten Defic Hyperact Disord. 2017;9(1):47–65. doi: 10.1007/s12402-016-0208-3.
    1. Young S, Moss D, Sedgwick O, Fridman M, Hodgkins P. A meta-analysis of the prevalence of attention deficit hyperactivity disorder in incarcerated populations. Psychol Med. 2015;45(2):247–258.
    1. Young S, Sedgwick O, Fridman M, Gudjonsson G, Hodgkins P, Lantigua M, et al. Co-morbid psychiatric disorders among incarcerated ADHD populations: a meta-analysis. Psychol Med. 2015;45(12):2499–2510.
    1. Elsabbagh M, Divan G, Koh Y-J, Kim YS, Kauchali S, Marcín C, et al. Global prevalence of ASD and other pervasive developmental disorders. Autism Res. 2012;5(3):160–179.
    1. Christensen DL, Maenner MJ, Bilder D, Constantino JN, Daniels J, Durkin MS, et al. Prevalence and characteristics of autism spectrum disorder among children aged 4 years – early autism and developmental disabilities monitoring network, seven sites, United States, 2010, 2012, and 2014. MMWR Surveill Summ. 2019;68(2):1–19. doi: 10.15585/mmwr.ss6802a1.
    1. Murphy CM, Wilson CE, Robertson DM, Ecker C, Daly EM, Hammond N, et al. Autism spectrum disorder in adults: diagnosis, management, and health services development. Neuropsychiatr Dis Treat. 2016;12:1669–1686.
    1. Pourcain BS, Mandy WP, Heron J, Golding J, Smith GD, Skuse DH. Links between co-occurring social-communication and hyperactive-inattentive trait trajectories. J Am Acad Child Adolesc Psychiatry. 2011;50(9–6):892–902.
    1. Robinson EB, Munir K, Munafò MR, Hughes M, McCormick MC, Koenen KC. Stability of autistic traits in the general population: further evidence for a continuum of impairment. J Am Acad Child Adolesc Psychiatr. 2011;50(4):376–384.
    1. World Health Organization. (2018). WHO releases new International Classification of Diseases (ICD 11). June 18, 2018. . Accessed 23 June 2019.
    1. Levy SE, Giarelli E, Lee LC, Schieve LA, Kirby RS, Cunniff C, et al. Autism spectrum disorder and co-occurring developmental, psychiatric, and medical conditions among children in multiple populations of the United States. J Dev Behav Pediatr. 2010;31(4):267–275.
    1. Simonoff E, Pickles A, Charman T, Chandler S, Loucas T, Baird G. Psychiatric disorders in children with autism spectrum disorders: prevalence, comorbidity, and associated factors in a population-derived sample. J Am Acad Child Adolesc Psychiatry. 2008;47(8):921–929.
    1. Hofvander B, Delorme R, Chaste P, Nydén A, Wentz E, Ståhlberg O, et al. Psychiatric and psychosocial problems in adults with normal-intelligence autism spectrum disorders. BMC Psychiatry. 2009;9(1):35.
    1. Howlin P, Magiati I. Autism spectrum disorder: outcomes in adulthood. Curr Opin Psychiatry. 2017;30(2):69–76.
    1. Rommelse NN, Franke B, Geurts HM, Hartman CA, Buitelaar JK. Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder. Eur Child Adolescent Psychiatry. 2010;19(3):281–295.
    1. Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet. 2013;45(9):984–994.
    1. Ronald A, Simonoff E, Kuntsi J, Asherson P, Plomin R. Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample. J Child Psychol Psychiatry. 2008;49(5):535–542.
    1. Antshel KM, Zhang-James Y, Faraone SV. The comorbidity of ADHD and autism spectrum disorder. Expert Review Neurother. 2013;13(10):1117–1128.
    1. Jung M, Tu Y, Park J, Jorgenson K, Lang C, Song W, et al. Surface-based shared and distinct resting functional connectivity in attention deficit hyperactivity disorder and autism spectrum disorder. Br J Psychiatry. 2019;214(6):339–344.
    1. Christakou A, Murphy CM, Chantiluke K, Cubillo AI, Smith AB, Giampietro V, et al. Disorder-specific functional abnormalities during sustained attention in youth with attention deficit hyperactivity disorder (ADHD) and with autism. Mol Psychiatry. 2013;18(2):236–244. doi: 10.1038/mp.2011.185.
    1. Chantiluke K, Christakou A, Murphy CM, Giampietro V, Daly EM, Ecker C, et al. Disorder-specific functional abnormalities during temporal discounting in youth with attention deficit hyperactivity disorder (ADHD), autism and comorbid ADHD and autism. Psychiatry Res. 2014;223(2):113–120.
    1. Boedhoe PSW, van Rooij D, Hoogman M, Twisk JWR, Schmaal L, Abe Y, et al. Subcortical brain volume, regional cortical thickness and surface area variations across attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and obsessive-compulsive disorder (OCD). In submission. Am J Psychiatry Preprint available doi. 10.1101/673012.
    1. Kern JK, Geier DA, Sykes LK, Geier MR, Deth RC. Are ASD and ADHD a continuum? A comparison of pathophysiological similarities between the disorders. J Atten Disord. 2015;19(9):805–827.
    1. Corbett BA, Constantine LJ, Hendren R, Rocke D, Ozonoff S. Examining executive functioning in children with autism spectrum disorder, attention deficit hyperactivity disorder and typical development. Psychiatry Res. 2009;166(2–3):210–222.
    1. Leitner Y. The co-occurrence of autism and attention deficit hyperactivity disorder in children – what do we know? Front Hum Neurosci. 2014;8(268):1–8. doi: 10.3389/fnhum.2014.00268.
    1. Sinzig J, Walter D, Doepfner M. Attention deficit/hyperactivity disorder in children and adolescents with autism spectrum disorder: symptom or syndrome? J Atten Disord. 2009;13(2):117–126.
    1. Lee DO, Ousley OY. Attention-deficit hyperactivity disorder symptoms in a clinic sample of children and adolescents with pervasive developmental disorders. J Child Adolescent Psychopharmacol. 2007;16(6):737–746.
    1. Leyfer OT, Folstein SE, Bacalman S, Davis NO, Dinh E, Morgan J, et al. Comorbid psychiatric disorders in children with autism: interview development and rates of disorders. J Autism Dev Disord. 2006;36(7):849–861.
    1. Young S, González R, Mullens H, Mutch L, Mallet-Lambert I, Gudjonsson GH. Neurodevelopmental disorders in prison inmates: comorbidity and combined associations with psychiatric symptoms and behavioural disturbance. Psychiatry Res. 2018;261:109–115.
    1. Culpin I, Mars B, Pearson RM, Golding J, Heron J, Bubak I, et al. Autistic traits and suicidal thoughts, plans, and self-harm in late adolescence: population-based cohort study. J Am Acad Child Adolesc Psychiatry. 2018;57(5):313–320.
    1. Hirvikoski T, Mittendorfer-Rutz E, Boman M, Larsson H, Lichtenstein P, Bölte S. Premature mortality in autism spectrum disorder. Br J Psychiatry. 2016;208(3):232–238.
    1. Skirrow C, McLoughlin G, Kuntsi J, Asherson P. Behavioral, neurocognitive and treatment overlap between attention-deficit/hyperactivity disorder and mood instability. Expert Rev Neurother. 2009;9(4):489–503. doi: 10.1586/ern.09.2.
    1. Karam RG, Breda V, Picon FA, Rovaris DL, Victor MM, Salgado CAI, et al. Persistence and remission of ADHD during adulthood: a 7-year clinical follow-up study. Psychol Med. 2015;45(10):2045–2056.
    1. Gershon J. A meta-analytic review of gender differences in ADHD. J Atten Disord. 2002;5(3):143–154.
    1. Lai MC, Lombardo MV, Auyeung B, Chakrabarti B, Baron-Cohen S. Sex/gender differences and autism: setting the scene for future research. J Am Acad Child Adolesc Psychiatry. 2015;54(1):11–24.
    1. Gaub M, Carlson CL. Gender differences in ADHD: a meta-analysis and critical review. J Am Acad Child Adolesc Psychiatry. 1997;36(8):1036–1045.
    1. Mandy W, Chilvers R, Chowdhury U, Salter G, Seigal A, Skuse D. Sex differences in autism spectrum disorder: evidence from a large sample of children and adolescents. J Autism Dev Disord. 2012;42(7):1304–1313.
    1. Sun X, Allison C, Auyeung B, Zhang Z, Matthews FE, Baron-Cohen S, et al. Validation of existing diagnosis of autism in mainland China using standardised diagnostic instruments. Autism. 2015;19(8):1010–1017.
    1. Becker MM, Wagner MB, Bosa CA, Schmidt C, Longo D, Papaleo C, et al. Translation and validation of Autism Diagnostic Interview-Revised (ADI-R) for autism diagnosis in Brazil. Arq Neuropsiquiatr. 2012;70(3):185–190.
    1. Matson JL, Worley JA, Fodstad JC, Chung KM, Suh D, Jhin HK, et al. A multinational study examining the cross-cultural differences in reported symptoms of autism spectrum disorders: Israel, South Korea, the United Kingdom, and the United States of America. Res Autism Spectr Disord. 2011;5(4):1598–1604.
    1. Sonuga-Barke EJS, Minocha K, Taylor EA, Sandberg S. Inter-ethnic bias in teachers’ ratings of childhood hyperactivity. Br J Dev Psychol. 1993;11(2):187–200.
    1. Larson K, Russ SA, Kahn RS, Halfon N. Patterns of comorbidity, functioning, and service use for US children with ADHD, 2007. Pediatrics. 2011;127(3):462–470.
    1. La Malfa G, Lassi S, Bertelli M, Salvini R, Placidi GF. Autism and intellectual disability: a study of prevalence on a sample of the Italian population. J Intellect Disabil Res. 2004;48(3):262–267.
    1. Wigham S, Rodgers J, Berney T, Le Couteur A, Ingham B, Parr JR. Psychometric properties of questionnaires and diagnostic measures for autism spectrum disorders in adults: a systematic review. Autism. 2019;23(2):287–305.
    1. Rutter M, Bailey A, Lord C. The Social Communication Questionnaire (SCQ). Manual. 2003. Los Angeles: Western Psychological Services.
    1. Constantino JN. Social Responsiveness Scale (SRS™-2), second edition. Manual. 2012.
    1. Skuse DH, Mandy WP, Scourfield J. Measuring autistic traits: heritability, reliability, and validity of the social communication disorders checklist. Br J Psychiatry. 2005;187:568–572.
    1. Conners KC. Comprehensive behavior rating scales. Manual. 2008.
    1. Conners KC, Erhardt D, Sparrow E. Conners’ Adult ADHD Rating Scales (CAARS). Manual. 1999.
    1. Swanson JM. The SNAP-IV Teacher and Parent Rating Scale. University of California, Irvine, CA 92715. . Accessed 24 Apr 2020.
    1. Ustun B, Adler LA, Rudin C, Faraone SV, Spencer TJ, Berglund P, et al. The World Health Organization adult attention-deficit/hyperactivity disorder self-report screening scale for DSM-5. JAMA Psychiatry. 2017;74(5):520–526.
    1. Young S. RATE and RATE-C Scales. 2007. . Accessed 24 Apr 2020.
    1. Wolraich M. The Vanderbilt ADHD diagnostic rating scale. . Assessed 23 June 2019.
    1. Scoring instructions for the NICHQ Vanderbilt Assessment Scales (pdf). American Academy of Pediatrics. . Assessed 23 June 2019.
    1. K-SADS-PL Screener (2016). . Accessed 21 Apr 2019.
    1. K-SADS-PL DSM-5 Supplement 4: Neurodevelopmental, disruptive and conduct disorders supplement (2016). . Accessed 21 Apr 2019.
    1. The Strengths and Difficulties Questionnaire. . Accessed 21 Apr 2019.
    1. Goodman R, Ford T, Richards H, Gatward R, Meltzer H. The development and well-being assessment: description and initial validation of an integrated assessment of child and adolescent psychopathology. J Child Psychol Psychiatry Allied Disciplines. 2000;41:645–655.
    1. McEwen Fiona S., Stewart Catherine S., Colvert Emma, Woodhouse Emma, Curran Sarah, Gillan Nicola, Hallett Victoria, Lietz Stephanie, Garnett Tracy, Ronald Angelica, Murphy Declan, Happé Francesca, Bolton Patrick. Diagnosing autism spectrum disorder in community settings using the Development and Well-Being Assessment: validation in a UK population-based twin sample. Journal of Child Psychology and Psychiatry. 2015;57(2):161–170.
    1. Young S. Diagnostic Autism Specftrum Interview. 2020. . Accessed 24 Apr 2020.
    1. Rutter M, Le Couteur A, Lord C. ADRI-R: Autism Diagnostic Interview-Revised (ADI-R). 2003. Western Psychological Services, Los Angeles. Accessed 21 Apr 2019.
    1. Wing L, Leekam S, Libby S, Gould J, Larcombe M. The diagnostic interview for social and communication disorders: background, inter-rater reliability and clinical use. J Child Psychol Psychiatry. 2002;43(3):307–325.
    1. Skuse D, Warrington R, Bishop D, Chowdhury U, Lau J, Mandy W, et al. The developmental, dimensional and diagnostic interview (3Di): a novel computerized assessment for autism spectrum disorders. J Am Acad Child Adolesc Psychiatry. 2004;43(5):548–558.
    1. Young S. ACE: ADHD Child Interview. 2015. . Accessed 24 Apr 2020.
    1. Young S. ACE+: ADHD Interview Adult. 2016. . Accessed 24 Apr 2020.
    1. Kooij JJ. Adult ADHD: diagnostic assessment and treatment. 3. London: Springer; 2013.
    1. Furczyk K, Thorne J. Adult ADHD and suicide. Atten Defic Hyperact Disord. 2014;6(3):153–158.
    1. Veenstra-VanderWeele J. Recognizing the problem of suicidality in autism spectrum disorder. J Am Acad Child Adolesc Psychiatry. 2018;57(5):302–303.
    1. Lord C, Luyster RJ, Gotham K, Guthrie W. Autism diagnostic observation schedule, second edition (ADOS-2) manual (part II): toddler module. Torrance: Western Psychological Services; 2012.
    1. Lord C, Rutter M, DiLavore PC, Risi S, Gotham K, Bishop S. Autism diagnostic observation schedule, second edition (ADOS-2) manual (part I): modules 1–4. Torrance: Western Psychological Services; 2012.
    1. Wechsler D. Wechsler intelligence scale for children-fifth edition. Bloomington: Pearson; 2014.
    1. Wechsler D. Wechsler adult intelligence scale - fourth edition. Bloomington: Pearson; 2008.
    1. Harrison P, Oakland T. Adaptive behavior assessment (ABAS-3) – third edition. Bloomington: Pearson; 2015.
    1. Sparrow SS, Cicchetti DV, Saulnier CA. Vineland adaptive behavior scales (Vineland-3) - third edition. Bloomington: Pearson; 2016.
    1. Kaufman AS, Kaufman NL. Kaufman assessment battery for children. Second edition. Normative update. Bloomington: Pearson; 2018.
    1. Conners CK. Conners’ continuous performance test - third edition. Bloomington: Pearson; 2014.
    1. Ulberstad F. QbTest technical manual. rev. ed. Stockholm: QbTech AB; 2012.
    1. Young S, Amarasinghe JA. Practitioner review: non-pharmacological treatments for ADHD: a lifespan approach. J Child Psychol Psychiatry. 2010;51(2):116–133.
    1. Pickles A, Le Couteur A, Leadbitter K, Salomone E, Cole-Fletcher R, Tobin H, et al. Parent-mediated social communication therapy for young children with autism (PACT): long-term follow-up of a randomized controlled trial. Lancet. 2016;388(10059):2501–2509.
    1. Green J, Charman T, McConachie H, Aldred C, Slonims V, Howlin P, et al. Parent-mediated communication-focused treatment in children with autism (PACT): a randomized controlled trial. Lancet. 2010;375(9732):2152–2160.
    1. Kasan C, Gulsrud A, Paparella T, Hellemann G, Berry K. Randomized comparative efficacy study of parent-mediated interventions for toddlers with autism. J Consult Clin Psychol. 2015;83(3):554–563.
    1. Smith T, Iadarola S. Evidence base update for autism spectrum disorder. J Clin Child Adolesc Psychol. 2015;44(5):897–922.
    1. Young Susan, Smith Jade. Helping Children with ADHD. Chichester, UK: John Wiley & Sons, Ltd; 2017.
    1. Young S. The STAR detective facilitator manual: a cognitive behavioral group intervention to develop skilled thinking and reasoning for children with cognitive, behavioral, emotional and social problems. London: Jessica Kingsley; 2017.
    1. Young S. Becoming a STAR detective!: your detective’s notebook for finding clues to how you feel. London: Jessica Kingsley; 2017.
    1. Marshall D, Thomas T. Polygraphs and sex offenders: the truth is out there. Probation J. 2015;62(2):128–139.
    1. Gudjonsson GH, Vrij A. A review of the current scientific status and fields of application of polygraphic deception of detection. Leicester: British Psychological Society; 2004. p. 1–31.
    1. Pfiffner LJ, Rooney M, Haack L, Villodas M, Delucchi K, McBurnett K. A randomized controlled trial of a school-implemented school-home intervention for attention-deficit/hyperactivity disorder symptoms and impairment. J Am Acad Child Adolesc Psychiatry. 2016;55(9):762–770.
    1. Pfiffner LJ, Rooney ME, Jiang Y, Haack LM, Beaulieu A, McBurnett K. Sustained effects of collaborative school-home intervention for attention-deficit/hyperactivity disorder symptoms and impairment. J Am Acad Child Adolesc Psychiatry. 2018;57(4):245–251.
    1. Shaw P, Eckstrand K, Sharp W, Blumenthal J, Lerch JP, Greenstein D, et al. Attention-deficit/hyperactivity disorder is characterized by a delay in cortical maturation. Proc Natl Acad Sci U S A. 2007;104(49):19649–19654.
    1. The Joint Council for Qualifications. . Accessed 28 Apr 2019.
    1. The Scottish Qualifications Authority. . Accessed 28 Apr 2019.
    1. Harpin VA. The effect of ADHD on the life of an individual, their family, and community from preschool to adult life. Arch Dis Child. 2005;90(suppl 1):i2–i7.
    1. Østergaard SD, Dalsgaard S, Faraone SV, Munk-Olsen T, Laursen TM. Teenage parenthood and birth rates for individuals with and without attention-deficit/hyperactivity disorder: a nationwide cohort study. J Am Acad Child Adolesc Psychiatry. 2017;56(7):578–584.
    1. Emilsson, Gudjonsson G, Sigurdsson JF, Einarsson E, Baldursson G, Olafsdottir H, et al. Cognitive behaviour therapy in medication-treated adults with ADHD and persistent symptoms: a randomized controlled trial. BMC Psychiatry. 2011;11:116.
    1. Young S, Khondoker M, Emilsson B, Sigurdsson JF, Philipp-Wiegmann F, Baldursson G, et al. A randomized controlled trial reporting functional outcomes of cognitive behavioural therapy in medication-treated adults with ADHD and comorbid psychopathology. Eur Arch Psychiatry Clin Neurosci. 2017;267(3):267–276. doi: 10.1007/s00406-016-0735-0.
    1. Young S, Khondoker M, Emilsson B, Sigurdsson JF, Philipp-Wiegmann F, Baldursson G, Olafsdottir H, Gudjonsson G. Cognitive behavioral therapy in medication-treated adults with ADHD and comorbid psychopathology: a randomized controlled trial using multi-level analysis. Psychol Med. 2015;45(13):2793–2804.
    1. Waugh A, Gudjonsson GH, Rees-Jones A, Young S (2014). A feasibility study of the Reasoning and Rehabilitation Mental Health Programme (R&R2MHP) in male offenders with intellectual disability. Criminal Behaviour Mental Health. 2014; (24)222–4.
    1. Bramham J, Young S, Bickerdike Spain D, McCartan D, Xenitidis K. Evaluation of group cognitive behavioral therapy for adults with ADHD. J Atten Disord. 2009;12(5):434–441.
    1. Knouse LE, Teller J, Brooks MA. Meta-analysis of cognitive–behavioral treatments for adult ADHD. J Consult Clin Psychol. 2017;85(7):737–750.
    1. Spain D, Sin J, Chalder T, Murphy D, Happe F. Cognitive behaviour therapy for adults with autism spectrum disorders and psychiatric co-morbidity: a review. Res Autism Spectr Disord. 2015;9:151–162.
    1. Solanto MV, Marks DJ, Wasserstein J, Mitchell K, Abikoff H, Alvir JM, et al. Efficacy of meta-cognitive therapy for adult ADHD. Am J Psychiatry. 2010;167(8):958–968.
    1. Russell AJ, Jassi A, Fullana MA, Mack H, Johnston K, Heyman I, et al. Cognitive behavior therapy for comorbid obsessive-compulsive disorder in high-functioning autism spectrum disorders: a randomized controlled trial. Depress Anxiety. 2013;30(8):697–708.
    1. Russell AJ, Mataix-Cols D, Anson MA, Murphy DG. Psychological treatment for obsessive-compulsive disorder in people with autism spectrum disorders – a pilot study. Psychother Psychosom. 2009;78(1):59–61.
    1. Young S, Adamou M, Asherson P, Coghill D, Colley B, Gudjonsson G, et al. Recommendations for the transition of patients with ADHD from child to adult healthcare services: a consensus statement from the UK Adult ADHD Network. BMC Psychiatry. 2016;16:301. doi: 10.1186/s12888-016-1013-4.
    1. Young S, Murphy C, Coghill D. Avoiding the ‘twilight zone’: guidance and recommendations on ADHD and the transition between child and adult services. BMC Psychiatry. 2011;11:174.
    1. Civil Service Judgement Test: A guide for candidates. Accessed 07 May 2019. .
    1. Sturman N, Deckx L, van Driel ML. Methylphenidate for children and adolescents with autism spectrum disorder. Cochrane Database Syst Rev. 2017; 10.1002/14651858.CD011144.pub2.
    1. Reichow B, Volkmar FR, Bloch MH. Systematic review and meta-analysis of pharmacological treatment of the symptoms of attention-deficit/hyperactivity disorder in children with pervasive developmental disorders. J Autism Dev Disord. 2013;43(10):2435–2441.
    1. Howes OD, Rogdaki M, Findon JL, Wichers RH, Charman T, King BH, et al. Autism spectrum disorder: consensus guidelines on assessment, treatment and research from the British Association for Psychopharmacology. J Psychopharmacol. 2018;32(1):3–29.
    1. Taylor DM, Barnes TR, Young AH. The Maudsley prescribing guidelines in psychiatry, 13th edition. Chichester: Wiley; 2018.
    1. Reiersen AM, Handen B. Commentary on ‘selective serotonin reuptake inhibitors (SSRIs) for autism spectrum disorders (ASD)’. Evid Based Child Health. 2011;6(4):1082–1085.
    1. Santosh PJ, Baird G, Pityaratstian N, Tavare E, Gringras P. Impact of comorbid autism spectrum disorders on stimulant response in children with attention deficit hyperactivity disorder: a retrospective and prospective effectiveness study. Child Care Health Dev. 2006;32(5):575–583.
    1. Politte LC, Scahill L, Figuera J, McCracken JT, King B, McDougle CJ. A randomized, placebo-controlled trial of extended-release guanfacine in childrenwith autism spectrum disorder and ADHD symptoms: an analysis of secondary outcome measures. Neuropsychopharmacol. 2018;43:1772–1778.
    1. Handen BL, Aman MG, Arnold LE, Hyman SL, Tumuluru RV, Lecavalier L, et al. Atomoxetine, parent training, and their combination in children with autism spectrum disorder and attention-deficit/hyperactivity disorder. J Am Acad ChildAdolesc Psychiatry. 2015;54:905–915.
    1. Friedland S, Walkup JT. Meta-assurance: no tic exacerbation caused by stimulants. J Am Acad Child Adolesc Psychiatry. 2015;54(9):706–708.

Source: PubMed

3
Suscribir