Blood Disorders in Patients Undergoing Transcatheter Aortic Valve Replacement: A Review
Hugo De Larochellière, Rishi Puri, John W Eikelboom, Josep Rodés-Cabau, Hugo De Larochellière, Rishi Puri, John W Eikelboom, Josep Rodés-Cabau
Abstract
Transcatheter aortic valve replacement (TAVR) is well established for treating patients with severe aortic stenosis considered at intermediate to high surgical risk. Blood disorders such as anemia, thrombocytopenia, and acquired type 2A von Willebrand disease are relatively frequent in TAVR candidates, and multiple studies to date have highlighted their potential clinical association with mortality and/or bleeding complications post-TAVR. The present review provides an overview of various blood disorders observed pre- and post-TAVR, with special focus on their incidence, etiology, clinical association, and management.
Keywords: anemia; aortic stenosis; hemostasis; thrombocytopenia.
Copyright © 2019 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.
Source: PubMed