Is female genital mutilation/cutting associated with adverse mental health consequences? A systematic review of the evidence

Salma M Abdalla, Sandro Galea, Salma M Abdalla, Sandro Galea

Abstract

Introduction: The adverse physical consequences of female genital mutilation/cutting (FGM/C) have been thoroughly investigated and documented. Yet, we know little about the adverse mental health consequences of the practice. To fill this research gap, we systematically reviewed studies that assessed any adverse mental health consequences related to FGM/C.

Methods: We searched four databases from inception to 21 December 2018. We then reviewed all titles and abstracts for relevant studies. We used the National Institutes of Health quality assessment tool to appraise the quality of each study and the Newcastle-Ottawa Scale to rate the risk of bias within studies.

Results: We included 16 studies in this review; only six studies examined the association between FGM/C and adverse mental health outcomes as the sole research question. Among the included studies, 10 were conducted at the participants' country of origin. The sample size of the populations studied ranged from 3 to 4800 participants. Only one study received a rating of 'good' methodological quality.Fourteen of the 16 studies reported an association between FGM/C and at least adverse mental health outcome. These included eight studies that reported a higher burden of adverse mental health outcomes among women who underwent FGM compared with women who did not undergo FGM/C. Four studies reported a correlation between the severity of FGM/C and the severity of adverse mental health outcomes.

Conclusion: This systematic review documents an association between FGM/C and adverse mental health outcomes. Importantly, our review demonstrates the need for more rigorous research on the topic.

Keywords: FGM/C; PTSD; anxiety; depression; female genital mutilation/cutting; mental health.

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Flow chart describing the study selection process and number of articles retrieved, included and excluded.
Figure 2
Figure 2
Reviewers' judgement about risk of bias for each item across included studies.
Figure 3
Figure 3
Overview of studies examining the association between FGM/C and adverse mental health outcomes. FGM/C, female genital mutilation/cutting; PTSD, post-traumatic stress disorder.

References

    1. UNICEF Female genital mutilation, 2018. Available: [Accessed 26 Feb 2019].
    1. Kandala N-B, Ezejimofor MC, Uthman OA, et al. . Secular trends in the prevalence of female genital mutilation/cutting among girls: a systematic analysis. BMJ Glob Health 2018;3:e000549 10.1136/bmjgh-2017-000549
    1. WHO Female genital mutilation, 2018. Available: [Accessed 26 Feb 2019].
    1. Simpson J, Robinson K, Creighton SM, et al. . Female genital mutilation: the role of health professionals in prevention, assessment, and management. BMJ 2012;344:e1361 10.1136/bmj.e1361
    1. WHO Eliminating female genital mutilation: An interagency statement - OHCHR, UNAIDS, UNDP, UNECA, UNESCO, UNFPA, UNHCR, UNICEF, UNIFEM, WHO. WHO. Geneva 2018.
    1. WHO Female Genital Mutilation - Integrating the Prevention and the Management of the Health Complications into the curricula of nursing and midwifery: A Student’s Manual [Internet]. Geneva, 2001. Available: [Accessed 4 Mar 2019].
    1. Behrendt A, Moritz S. Posttraumatic Stress Disorder and Memory Problems After Female Genital Mutilation. Am J Psychiatry 2005;162:1000–2. 10.1176/appi.ajp.162.5.1000
    1. WHO Classification of female genital mutilation. World Health Organization, 2007.
    1. Leye E, Deblonde J, García-Añón J, et al. . An analysis of the implementation of laws with regard to female genital mutilation in Europe. Crime Law Soc Change 2007;47:1–31. 10.1007/s10611-007-9055-7
    1. Berg RC, Odgaard-Jensen J, Fretheim A, et al. . An updated systematic review and meta-analysis of the obstetric consequences of female genital mutilation/cutting. Obstet Gynecol Int 2014;2014:1:1–8. 10.1155/2014/542859
    1. Banks E, Meirik O, Farley T, et al. . Female genital mutilation and obstetric outcome: WHO collaborative prospective study in six African countries. Lancet 2006;367:1835–41. 10.1016/S0140-6736(06)68805-3
    1. Serour GI. Medicalization of female genital mutilation/cutting. African Journal of Urology 2013;19:145–9. 10.1016/j.afju.2013.02.004
    1. Berg RC, Underland V, Odgaard-Jensen J, et al. . Effects of female genital cutting on physical health outcomes: a systematic review and meta-analysis. BMJ Open 2014;4:e006316 10.1136/bmjopen-2014-006316
    1. Berg RC, Denison E, Psychological FA. Social and Sexual Consequences of Female Genital Mutilation/Cutting (FGM/C): A Systematic Review of Quantitative Studies [Internet]. Norwegian Knowledge Centre for the Health Services. Knowledge Centre for the Health Services at The Norwegian Institute of Public Health 2010. (cited 2019 Feb 26).
    1. Mulongo P, McAndrew S, Hollins Martin C. Crossing borders: Discussing the evidence relating to the mental health needs of women exposed to female genital mutilation. Int J Ment Health Nurs 2014;23:296–305. 10.1111/inm.12060
    1. Reisel D, Creighton SM. Long term health consequences of Female Genital Mutilation (FGM). Maturitas 2015;80:48–51. 10.1016/j.maturitas.2014.10.009
    1. Home - PubMed [Internet]. NCBI, 2019. Available: [Accessed 19 Jan 2019].
    1. Embase Embase, 2019. Available: [Accessed 27 Feb 2019].
    1. Web of Science Web of Science. Available: [Accessed 19 Jan 2019].
    1. PsycINFO PsycINFO | EBSCO [Internet], 2019. Available: [Accessed 27 Feb 2019].
    1. NIH Study Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies [Internet], 2019. Available: [Accessed 25 Feb 2019].
    1. Allen LN, Pullar J, Wickramasinghe KK, et al. . Evaluation of research on interventions aligned to WHO 'Best Buys' for NCDs in low-income and lower-middle-income countries: a systematic review from 1990 to 2015. BMJ Glob Health 2018;3:e000535 10.1136/bmjgh-2017-000535
    1. Wells G, Shea B, O’Connell D, et al. . The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses [Internet] 2000.
    1. Ahmed MR, Shaaban MM, Meky HK, et al. . Psychological impact of female genital mutilation among adolescent Egyptian girls: a cross-sectional study. The European Journal of Contraception & Reproductive Health Care 2017;22:280–5. 10.1080/13625187.2017.1355454
    1. Applebaum J, Cohen H, Matar M, et al. . Symptoms of Posttraumatic Stress Disorder After Ritual Female Genital Surgery Among Bedouin in Israel. Prim. Care Companion J. Clin. Psychiatry 2008;10:453–6. 10.4088/PCC.v10n0605
    1. Kizilhan JI. Impact of psychological disorders after female genital mutilation among Kurdish girls in northern Iraq. Eur J Psychiatry 2011;25(2):92–100.
    1. Köbach A, Ruf-Leuschner M, Elbert T. Psychopathological sequelae of female genital mutilation and their neuroendocrinological associations. BMC Psychiatry 2018;18:187 10.1186/s12888-018-1757-0
    1. Lever H, Ottenheimer D, Atkinson HG, et al. . Depression, Anxiety, Post-traumatic Stress Disorder and a History of Pervasive Gender-Based Violence Among Women Asylum Seekers Who Have Undergone Female Genital Mutilation/Cutting: A Retrospective Case Review. J Immigr Minor Heal 2018.
    1. Akinsulure-Smith AM. Exploring female genital cutting among West African immigrants. J Immigrant Minority Health 2014;16:559–61. 10.1007/s10903-012-9763-7
    1. Chibber R, El-saleh E, El harmi J. Female circumcision: obstetrical and psychological sequelae continues unabated in the 21st century. The Journal of Maternal-Fetal & Neonatal Medicine 2011;24:833–6. 10.3109/14767058.2010.531318
    1. Daneshkhah F, Allahverdipour H, Jahangiri L, et al. . Mental Well-being and Quality of Life among Kurdish Circumcised Women in Iran. Iran J Public Health 2017;46:1265–74.
    1. Elnashar A, Abdelhady R. The impact of female genital cutting on health of newly married women. International Journal of Gynecology & Obstetrics 2007;97:238–44. 10.1016/j.ijgo.2007.03.008
    1. Knipscheer J, Vloeberghs E, van der Kwaak A, et al. . Mental health problems associated with female genital mutilation. BJPsych Bulletin 2015;39:273–7. 10.1192/pb.bp.114.047944
    1. Koolaee AK, Pourebrahim T, Mohammadmoradi B, et al. . The comparison of marital satisfaction and mental health in genital mutilated females and non-genital mutilated females. Int J high risk Behav Addict [Internet] 2012;1:115–20.
    1. Mahmoudi O, Hosseini E. Psychosexual complications of female genital mutilation for couples: A comparative study. J Kermanshah Univ Med Sci 2017;20:135–40.
    1. Pereda N, Arch M, Pérez-González A. A case study perspective on psychological outcomes after female genital mutilation. J Obstet Gynaecol 2012;32:560–5. 10.3109/01443615.2012.689893
    1. Vloeberghs E, van der Kwaak A, Knipscheer J, et al. . Coping and chronic psychosocial consequences of female genital mutilation in the Netherlands. Ethn Health 2012;17:677–95. 10.1080/13557858.2013.771148
    1. Vrachnis N, Salakos N, Iavazzo C, et al. . Female genital mutilation in Greece. Clin Exp Obstet Gynecol 2012;39:346–50.
    1. Turner RJ, Lloyd DA. Lifetime traumas and mental health: the significance of cumulative adversity. J Health Soc Behav 1995;36:360–76. 10.2307/2137325
    1. Fink DS, Galea S. Life course epidemiology of trauma and related psychopathology in civilian populations. Curr Psychiatry Rep 2015;17:31 10.1007/s11920-015-0566-0

Source: PubMed

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