Expert consensus-based clinical practice guidelines management of intravascular catheters in the intensive care unit

Jean-François Timsit, Julien Baleine, Louis Bernard, Silvia Calvino-Gunther, Michael Darmon, Jean Dellamonica, Eric Desruennes, Marc Leone, Alain Lepape, Olivier Leroy, Jean-Christophe Lucet, Zied Merchaoui, Olivier Mimoz, Benoit Misset, Jean-Jacques Parienti, Jean-Pierre Quenot, Antoine Roch, Matthieu Schmidt, Michel Slama, Bertrand Souweine, Jean-Ralph Zahar, Walter Zingg, Laetitia Bodet-Contentin, Virginie Maxime, Jean-François Timsit, Julien Baleine, Louis Bernard, Silvia Calvino-Gunther, Michael Darmon, Jean Dellamonica, Eric Desruennes, Marc Leone, Alain Lepape, Olivier Leroy, Jean-Christophe Lucet, Zied Merchaoui, Olivier Mimoz, Benoit Misset, Jean-Jacques Parienti, Jean-Pierre Quenot, Antoine Roch, Matthieu Schmidt, Michel Slama, Bertrand Souweine, Jean-Ralph Zahar, Walter Zingg, Laetitia Bodet-Contentin, Virginie Maxime

Abstract

The French Society of Intensive Care Medicine (SRLF), jointly with the French-Speaking Group of Paediatric Emergency Rooms and Intensive Care Units (GFRUP) and the French-Speaking Association of Paediatric Surgical Intensivists (ADARPEF), worked out guidelines for the management of central venous catheters (CVC), arterial catheters and dialysis catheters in intensive care unit. For adult patients: Using GRADE methodology, 36 recommendations for an improved catheter management were produced by the 22 experts. Recommendations regarding catheter-related infections' prevention included the preferential use of subclavian central vein (GRADE 1), a one-step skin disinfection(GRADE 1) using 2% chlorhexidine (CHG)-alcohol (GRADE 1), and the implementation of a quality of care improvement program. Antiseptic- or antibiotic-impregnated CVC should likely not be used (GRADE 2, for children and adults). Catheter dressings should likely not be changed before the 7th day, except when the dressing gets detached, soiled or impregnated with blood (GRADE 2- adults). CHG dressings should likely be used (GRADE 2+). For adults and children, ultrasound guidance should be used to reduce mechanical complications in case of internal jugular access (GRADE 1), subclavian access (Grade 2) and femoral venous, arterial radial and femoral access (Expert opinion). For children, an ultrasound-guided supraclavicular approach of the brachiocephalic vein was recommended to reduce the number of attempts for cannulation and mechanical complications. Based on scarce publications on diagnostic and therapeutic strategies and on their experience (expert opinion), the panel proposed definitions, and therapeutic strategies.

Keywords: Bacteremia; Catheter; Critically ill; Infection; Prevention; Sepsis.

Conflict of interest statement

JFT: Research Grant from 3M, Astelas, Merck, Pfizer, Biomerieux to my university. Lectures in symposium:3M, Merck, Biomerieux, Novartis, Pfizer, Gilead. Participation to scientific board: Merck, 3M, Pfizer, Nabriva, Bayer Pharma, Gilead.

MD: Grant from MSD, lecture for MSD, Astellas, Gilead and participation to meeting from Gilead.

ML: Lectures for 3M, Aspen, BioMerieux, MSD, Octopharma, Orion, Pfizer; Consulting for Amomed, Aguettant; Travel expense: LFB.

AL: consulting for Fresenius. Lecture in symposium: Pfizer.

OM: Grant and lecture for BD, 3M.

MSc: lecture for Getinge, 3M, Drager.

BS: lecture for MSD. Participation to medical meeting for Gilead, Bard; IDSA meeting for Sanofi.

JRZ: Grant from MDS, lecture for MSD, EUMEDICA, Pfizer, Correvio.

The remaining authors declare no conflict of interest.

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