Acupuncture for the induction of labour: a double-blind randomised controlled study

J Modlock, B B Nielsen, N Uldbjerg, J Modlock, B B Nielsen, N Uldbjerg

Abstract

Objective: To investigate whether acupuncture is effective for the induction of labour in post-term pregnancies.

Design: A double-blind multicentre randomised controlled study.

Settings: Aarhus University Hospital and Herning Regional Hospital, Denmark.

Population: One hundred and twenty-five healthy women with uneventful pregnancies at gestational week 41(+6) were randomised into two groups.

Methods: The intervention group was given acupuncture twice on the same day at acupuncture point GV20 and bilaterally at points BL67, LI4 and SP6. The control group received sham acupuncture at the same points.

Main outcome measures: At effect evaluation, which was carried out 24 hours after randomisation, the primary endpoint was labour or delivery.

Results: The primary endpoint was achieved in seven women (12%) in the acupuncture group and eight women (14%) in the control group (P = 0.79). Stratification for parity and fetal gender did not alter the results.

Conclusion: Under the treatment regimen investigated in this study, acupuncture for the induction of labour in post-term women at gestational age 41(+6) weeks may not be effective.

Trial registration: ClinicalTrials.gov NCT00245752.

Figures

Figure 1
Figure 1
CONSORT flow diagram.

References

    1. Rabl M, Ahner R, Bitschnau M, Zeisler H, Husslein P. Acupuncture for cervical ripening and induction of labor at term—a randomized controlled trial. Wien Klin Wochenschr. 2001;113:942–6.
    1. Gaudernack LC, Forbord S, Hole E. Acupuncture administered after spontaneous rupture of membranes at term significantly reduces the length of birth and use of oxytocin. A randomized controlled trial. Acta Obstet Gynecol Scand. 2006;85:1348–53.
    1. Selmer-Olsen T, Lydersen S, Morkved S. Does acupuncture used in nulliparous women reduce time from prelabour rupture of membranes at term to active phase of labour? A randomised controlled trial. Acta Obstet Gynecol Scand. 2007;86:1447–52.
    1. Smith CA, Crowther CA, Collins CT, Coyle ME. Acupuncture to induce labor: a randomized controlled trial. Obstet Gynecol. 2008;112:1067–74.
    1. Lao L, Hamilton GR, Fu J, Berman BM. Is acupuncture safe? A systematic review of case reports. Altern Ther Health Med. 2003;9:72–83.
    1. MacPherson H, Thomas K, Walters S, Fitter M. The York Acupuncture Safety Study: prospective survey of 34 000 treatments by traditional acupuncturists. BMJ. 2001;323:486–7.
    1. State Standard of the People’s Republic of China . Location of Acupoints. 1st edn. Beijing, China: Foreign Languages Press; 1990.
    1. Deadman P, Baker K, Al-Khafaji M. A Manual of Acupuncture. 1st edn. Hove, UK: Journal of Chinese Medicine Publications; 1998.
    1. Park J, White A, Stevinson C, Ernst E, James M. Validating a new non-penetrating sham acupuncture device: two randomised controlled trials. Acupunct Med. 2002;20:168–74.
    1. Streitberger K, Kleinhenz J. Introducing a placebo needle into acupuncture research. Lancet. 1998;352:364–5.
    1. Altman DG, Schulz KF. Statistics notes: concealing treatment allocation in randomised trials. BMJ. 2001;323:446–7.
    1. Altman DG, Schulz KF, Moher D, Egger M, Davidoff F, Elbourne D, et al. The revised CONSORT statement for reporting randomized trials: explanation and elaboration. Ann Intern Med. 2001;134:663–94.
    1. Augensen K, Bergsjo P, Eikeland T, Askvik K, Carlsen J. Randomised comparison of early versus late induction of labour in post-term pregnancy. Br Med J (Clin Res Ed) 1987;294:1192–5.
    1. Kaptchuk TJ, Stason WB, Davis RB, Legedza AR, Schryer RN, Kerr CE, et al. Sham device vs inert pill: Randomised controlled trial of two placebo treatments. BMJ. 2006;332:391–7.

Source: PubMed

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