Asymptomatic and Human-to-Human Transmission of SARS-CoV-2 in a 2-Family Cluster, Xuzhou, China

Chunyang Li, Fang Ji, Liang Wang, Liping Wang, Jungui Hao, Mingjia Dai, Yan Liu, Xiucheng Pan, Juanjuan Fu, Li Li, Guangde Yang, Jianye Yang, Xuebing Yan, Bing Gu, Chunyang Li, Fang Ji, Liang Wang, Liping Wang, Jungui Hao, Mingjia Dai, Yan Liu, Xiucheng Pan, Juanjuan Fu, Li Li, Guangde Yang, Jianye Yang, Xuebing Yan, Bing Gu

Abstract

We report epidemiologic, laboratory, and clinical findings for 7 patients with 2019 novel coronavirus disease in a 2-family cluster. Our study confirms asymptomatic and human-to-human transmission through close contacts in familial and hospital settings. These findings might also serve as a practical reference for clinical diagnosis and medical treatment.

Keywords: 2019 novel coronavirus disease; COVID-19; China; SARS-CoV-2; Xuzhou; asymptomatic transmission; close contact; familial cluster; nosocomial transmission; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.

Figures

Figure
Figure
Chronology of a 2-family cluster of severe acute respiratory syndrome coronavirus 2 infection, including travel and contact history, in familial and hospital settings, Xuzhou, China, January 13–February 17, 2020. Dates of case confirmation, hospitalization, and discharge are labeled. Real-time fluorescent reverse transcription PCR for severe acute respiratory syndrome coronavirus 2 infection and corresponding results are indicated, together with the dates of chest CT. CT, computed tomography.

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Source: PubMed

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