Achievement of cardiometabolic goals among diabetic patients in Spain. A nationwide population-based study

Beatriz Navarro-Vidal, José R Banegas, Luz M León-Muñoz, Fernando Rodríguez-Artalejo, Auxiliadora Graciani, Beatriz Navarro-Vidal, José R Banegas, Luz M León-Muñoz, Fernando Rodríguez-Artalejo, Auxiliadora Graciani

Abstract

Background: No previous study has reported a comprehensive assessment of the attainment of cardiometabolic goals in the diabetic population of a European country. We examined the achievement of cardiometabolic goals among diabetics in Spain.

Methods and findings: A cross-sectional survey was performed in 2008-2010 among 12,077 individuals representative of the Spanish population aged ≥18 years. Information on cardiometabolic characteristics was collected at the participants' homes through structured questionnaires, physical examination, and fasting blood samples. Attainment of cardiometabolic goals was evaluated according to the most well-known guidelines. A total of 834 individuals had diabetes (fasting serum glucose ≥126 mg/dl, or glycosylated hemoglobin ≥6.5%,) or were being treated with oral antidiabetic drugs or insulin). Among diabetic patients, 661 (79.2%) were aware of their condition. Among the aware diabetic patients, only 11.4% had neither general (body mass index <25 kg/m(2)) nor abdominal obesity (waist circumference ≤102 cm in men and ≤88 cm in women), 8.6% consumed <7% of calories daily from saturated fats, and 41.1% achieved the recommendation on weekly physical activity. About 71% had glycosylated hemoglobin <7%, 22% had blood pressure <130/80 mmHg, and 36% reached the LDL-cholesterol goal of <100 mg/dl. Although a large proportion of aware diabetic individuals received lifestyle medical advice, only 38% of overweight individuals and 20% of daily smokers were offered a specific strategy for weight loss or quitting smoking, respectively.

Conclusions: In a European country with universal healthcare coverage, achievement of many cardiometabolic goals, in particular lifestyle, among aware diabetic individuals is poor. This suggests a need for improvement in both clinical guidelines' implementation and patients' adherence.

Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Figure 1. Percent distribution of the number…
Figure 1. Percent distribution of the number of cardiometabolic goals (lifestyles and biological factors) met among diabetic patients.
A.- Lifestyle: non-smoker; BMI <25 kg/m2 and waist circumference ≤102/88 cm in men and women, respectively; moderate or intense physical activity; energy intake from saturated fat <7%. B.- Biological factors: HbA1c<7%; blood pressure <130/80 mmHg; LDL cholesterol <100 mg/dl; urinary albumin:creatinine ratio <30 mg/g C.- Lifestyle and biological factors.

References

    1. Ekoé JM, Rewers M, Williams R, Zimmet P (2008) The epidemiology of diabetes mellitus. Second edition. Chichester: John Wiley & Sons Ltd.
    1. American Diabetes Association (2008) Standards of medical care in diabetes - 2008. Diabetes Care 31 (Suppl 1)S12–S54.
    1. Fourth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (Constituted by representatives of nine societies and by invited experts) (2007) European guidelines on cardiovascular disease prevention in clinical practice. Eur J Cardiovasc Prev Rehabil 14 (Suppl 2)S1–S113.
    1. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD) (2007) Guidelines on diabetes, pre-diabetes, and cardiovascular diseases. Eur Heart J 9 (Suppl C): C3–C74.
    1. Ford ES (2011) Trends in the control of risk factors for cardiovascular disease among adults with diagnosed diabetes: Findings from the National Health and Nutrition Examination Survey 1999–2008. J Diabetes 3: 337–47.
    1. Resnick HE, Foster GL, Bardsley J, Ratner RE (2006) Achievement of American Diabetes Association clinical practice recommendations among U.S. adults with diabetes, 1999–2002: the National Health and Nutrition Examination Survey. Diabetes Care 29: 531–7.
    1. Saydah SH, Fradkin J, Cowie CC (2004) Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes. JAMA 291: 335–42.
    1. Charpentier G, Genes N, Vaur L, Charpentier G, Genès N, et al. (2003) Control of diabetes and cardiovascular risk factors in patients with type 2 diabetes: a nationwide French survey. Diabetes Metab 29: 152–8.
    1. Coscelli C, Cucinotta D, Malini P, Manzato E, Nicolucci A, on behalf of the SFIDA Study Group e Italian Association of Diabetologists (AMD) (2005) Cardiovascular risk factors and metabolic control in type 2 diabetic subjects attending outpatient clinics in Italy: The SFIDA (survey of risk factors in Italian diabetic subjects by AMD) study Nutrition. Nutr Metab Cardiovasc Dis 15: 204–11.
    1. Rodríguez-Artalejo F, Graciani A, Guallar-Castillón P, León-Muñoz LM, Zuluaga MC, et al. (2011) Rationale and Methods of the Study on Nutrition and Cardiovascular Risk in Spain (ENRICA). Rev Esp Cardiol 64: 876–82.
    1. Pols MA, Peeters PH, Ocké MC, Slimani N, Bueno-de-Mesquita HB, et al. (1979) Estimation of reproducibility and relative validity of the questions included in the EPIC Physical Activity Questionnaire. Int J Epidemiol 26 (Suppl 1)S181–9.
    1. EPIC group of Spain (1997) Relative validity and reproducibility of a diet history questionnaire in Spain. II. Nutrients. EPIC Group of Spain. European Prospective Investigation into Cancer and Nutrition. Int J Epidemiol 26 (Suppl 1)S100–S9.
    1. Ortega-Anta RM, López-Sobaler AM, Carvajales PA, Requejo-Marcos AM, Molinero-Casares LM (2007) Programa DIAL. Available from: . Accessed on Dec 2, 2011.
    1. U.S. Department of Agriculture, ARS (2010) National Nutrient Database for Standard Reference. Available: . Accessed Dec 2, 2011.
    1. Gutiérrez-Fisac JL, Guallar-Castillón P, León-Muñoz LM, Graciani A, Banegas JR, et al. (2012) Prevalence of general and abdominal obesity in the adult population of Spain, 2008–2010. the ENRICA study. Obes Rev 13: 388–92.
    1. Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, et al. (2005) for the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research Recommendations for blood pressure measurement in humans and experimental animals: Part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on High Blood Pressure Research. Hypertension 45: 142–61.
    1. Lloyd-Jones DM, Hong Y, Labarthe D, Mozaffarian D, Appel LJ, et al. (2010) for the American Heart Association Strategic Planning Task Force and Statistics Committee Defining and Setting National Goals for Cardiovascular Health Promotion and Disease Reduction: The American Heart Association’s Strategic Impact Goal Through 2020 and Beyond. Circulation 121: 586–613.
    1. Bach-Faig A, Fuentes-Bol C, Ramos D, Carrasco JL, Roman B, et al. (2011) The Mediterranean diet in Spain: adherence trends during the past two decades using the Mediterranean Adequacy Index. Public Health Nutr 14: 622–8.
    1. Meyers CD, McCarren M, Wong ND, Abraira C, Duckworth WC, et al. (2006) for VADT Investigators Baseline achievement of lipid goals and usage of lipid medications in patients with diabetes mellitus (from the Veterans Affairs Diabetes Trial). Am J Cardiol 98: 63–5.
    1. Banegas JR, López-García E, Dallongeville J, Guallar E, Halcox JP, et al. (2011) Achievement of treatment goals for primary prevention of cardiovascular disease in clinical practice across Europe: the EURIKA study. Eur Heart J 32: 2143–52.
    1. Dorsey R, Songer T (2011) Lifestyle Behaviors and Physician Advice for Change Among Overweight and Obese Adults With Prediabetes and Diabetes in the United States, 2006. Prev Chronic Dis 8: A132.
    1. Schauer GL, Halperin AC, Mancl LA, Doescher MP (2011) Health professional advice for smoking and weight in adults with and without diabetes: findings from BRFSS. J Behav Med doi:10.1007/s10865-011-9386-9.
    1. Donker GA, Fleming DM, Schellevis FG, Spreeuwenberg P (2004) Differences in treatment regimes, consultation frequency and referral patterns of diabetes mellitus in general practice in five European countries. Fam Pract 21: 364–9.
    1. Rosen AB (2006) Indications for and utilization of ACE inhibitors in older individuals with diabetes. Findings from the National Health and Nutrition Examination Survey 1999 to 2002. J Gen Intern Med 21: 315–9.
    1. Prévost G, Phan TM, Mounier-Vehier C, Fontaine P (2005) Control of cardiovascular risk factors in patients with type 2 diabetes and hypertension in a French national study (Phenomen). Diabetes Metab 31: 479–85.
    1. Pignone M, Alberts MJ, Colwell JA, Cushman M, Inzucchi SE, et al. (2010) Aspirin for Primary Prevention of Cardiovascular Events in People with Diabetes: A Position Statement of the American Diabetes Association, a Scientific Statement of the American Heart Association, and an Expert Consensus Document of the American College of Cardiology Foundation. J Am Coll Cardiol 55: 2878–86.
    1. Nicolucci A, Standl E (2011) Antiplatelet therapy for every diabetic person? Diabetes Care 34 (Suppl 2)150–4.
    1. Centers of Disease Control and Prevention (2004) Influenza and pneumococcal vaccination coverage among persons aged ≥65 years and persons aged 18–64 years with diabetes or asthma- United States 2003. MMWR 53: 1007–12.
    1. Soriguer F, Goday A, Bosch-Comas A, Bordiú E, Calle-Pascual A, et al. (2012) Prevalence of diabetes mellitus and impaired glucose regulation in Spain: the Di@bet.es Study. Diabetologia. 55: 88–93.
    1. Galan I, Rodríguez-Artalejo F, Zorrilla B (2004) Telephone versus face-to-face household interviews in the assessment of health behaviors and preventive practices. Gac Sanit 18: 440–50.
    1. De León AC, Rodríguez JC, Coello SD, Pérez Mdel C, Díaz BB, et al... (2009) Lifestyle and treatment adherence of type 2 diabetes mellitus people in the Canary Islands. Rev Esp Salud Publica 83: 567–75. [Article in Spanish].

Source: PubMed

3
Suscribir