Intussusception Cases Among Children Admitted to Referral Hospitals in Kenya, 2002-2013: Implications for Monitoring Postlicensure Safety of Rotavirus Vaccines in Africa
Richard Omore, Francis Osawa, Janet Musia, Brian Rha, Amina Ismail, Nicholas Mukaria Kiulia, Fenny Moke, John Vulule, Anthony Mungai Wainaina, John Tole, Stanley Mugambi Machoki, J Pekka Nuorti, Robert F Breiman, Umesh D Parashar, Joel M Montgomery, Jacqueline E Tate, Richard Omore, Francis Osawa, Janet Musia, Brian Rha, Amina Ismail, Nicholas Mukaria Kiulia, Fenny Moke, John Vulule, Anthony Mungai Wainaina, John Tole, Stanley Mugambi Machoki, J Pekka Nuorti, Robert F Breiman, Umesh D Parashar, Joel M Montgomery, Jacqueline E Tate
Abstract
To describe the epidemiology of intussusception before introduction of the rotavirus vaccine, we reviewed the records of 280 patients younger than 5 years who were hospitalized in Kenya between 2002 and 2013. The patients who died (18 [6.4%]) had sought care later after symptom onset than the patients who survived (median, 5 vs 3 days, respectively; P = .04). Seeking prompt care may improve therapeutic outcomes.
Keywords: Kenya; childhood mortality; intussusception; risk factors.
Conflict of interest statement
Potential conflicts of interest. All authors: No reported conflicts.
All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.
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Source: PubMed