Early Postoperative Effects of Cataract Surgery on Anterior Segment Parameters in Primary Open-Angle Glaucoma and Pseudoexfoliation Glaucoma

Ufuk Elgin, Emine Şen, Tülay Şimşek, Kemal Tekin, Pelin Yılmazbaş, Ufuk Elgin, Emine Şen, Tülay Şimşek, Kemal Tekin, Pelin Yılmazbaş

Abstract

Objectives: To compare the effect of cataract surgery on anterior segment parameters measured by optical biometry in primary open-angle glaucoma (POAG) and pseudoexfoliation glaucoma (PXG).

Materials and methods: Twenty-five eyes of 25 patients with POAG and 29 eyes of 29 patients with PXG who had uncomplicated phacoemulsification and posterior chamber intraocular lens implantation surgery were included to our prospective study. Central corneal thickness (CCT), anterior chamber depth (ACD) and axial length (AL) were measured with an optical biometer preoperatively and at 1 month postoperatively. The pre- and postoperative values of intraocular pressure (IOP) and the anterior segment parameters and the differences between POAG and PXG were compared statistically by paired t, independent t and chi-square tests.

Results: The mean values of preoperative CCT (p=0.042) and ACD (p=0.012) were significantly lower in the PXG than in the POAG group. In the PXG group, IOP decreased (p=0.001) but CCT (p=0.03) and ACD (p=0.001) increased significantly postoperatively; AL did not change significantly. In the POAG group, IOP decreased (p=0.01) and ACD (p=0.004) increased significantly postoperatively, while AL and CCT did not change significantly. There were no significant differences in the pre- to postoperative changes in IOP (p=0.76), AL (p=0.44) and CCT (p=0.52) values between the two groups. However, the postoperative increase in ACD was larger in the PXG group (p=0.03).

Conclusion: Cataract surgery may cause some changes in IOP and anterior segment parameters like ACD and CCT postoperatively in eyes with POAG and PXG, and these changes may differ between eyes with PXG and POAG.

Keywords: Cataract; anterior segment parameters; optical biometer; primary open-angle glaucoma; pseudoexfoliation glaucoma.

Conflict of interest statement

No conflict of interest was declared by the authors. Financial Disclosure: The authors declared that this study received no financial support.

References

    1. Shrivastava A, Singh K. The effect of cataract extraction on intraocular pressure. Curr Opin Ophthalmol. 2010;21:118–122.
    1. Kronberg BP, Rhee DJ. Anterior segment imaging and the intraocular pressure lowering effect of cataract surgery for open and narrow angle glaucoma. Semin Ophthalmol. 2012;27:149–154.
    1. Hayashi K, Hayashi H, Nakao F, Hayashi F. Effect of cataract surgery on intraocular pressure control in glaucoma patients. J Cataract Refract Surg. 2001;27:1779–1786.
    1. Poley BJ, Lindstrom RL, Samuelson TW, Schulze R., Jr Intraocular pressure reduction after phacoemulsification with intraocular lens implantation in glaucomatous and nonglaucomatous eyes: evaluation of a causal relationship between the natural lens and open-angle glaucoma. J Cataract Refract Surg. 2009;35:1946–1955.
    1. Mansberger SL, Gordon MO, Jampel H, Bhorade A, Brandt JD, Wilson B, Kass MA Ocular Hypertension Treatment Study Group. Reduction in intraocular pressure after cataract extraction: the Ocular Hypertension Treatment Study. Ophthalmology. 2012;119:1826–1831.
    1. Huang G, Gonzalez E, Lee R, Chen YC, He M, Lin SC. Association of biometric factors with anterior chamber angle widening and intraocular pressure reduction after uneventful phacoemulsification for cataract. J Cataract Refract Surg. 2012;38:108–116.
    1. Zhao Q, Li N, Zhong X. Determination of anterior segment changes with Pentacam after phacoemulsification in eyes with primary angle-closure glaucoma. Clin Experiment Ophthalmol. 2012;40:786–791.
    1. Uçakhan OO, Ozkan M, Kanpolat A. Anterior chamber parameters measured by the Pentacam CES after uneventful phacoemulsification in normotensive eyes. Acta Ophthalmol. 2009;87:544–548.
    1. Dooley I, Charalampidou S, Malik A, Loughman J, Molloy L, Beatty S. Changes in intraocular pressure and anterior segment morphometry after uneventful phacoemulsification cataract surgery. Eye (Lond) 2010;24:519–526.
    1. Yang HS, Lee J, Choi S. Ocular biometric parameters associated with intraocular pressure reduction after cataract surgery in normal eyes. Am J Ophthalmol. 2013;156:89–94.
    1. Doğan M, Polat O, Karadaş M, Küspeci T, Yavaş G, İnan S, İnan Ü. Kataraktı olan gözlerde göz içi lens gücü hesaplanmasında parsiyel kohorens interferometri ile optik düşük kohorens reflektometri yöntemlerinin karşılaştırılması. Turk J Ophthalmol. 2014;44:419–423.
    1. Çankaya C, Doğanay S. Göz içi lens gücü hesaplaması ve optik biometri. Glo-Kat. 2011;6:207–214.
    1. Shen P, Ding X, Congdon NG, Zheng Y, He M. Comparison of anterior ocular biometry between optical low-coherence reflectometry and anterior segment optical coherence tomography in an adult Chinese population. J Cataract Refract Surg. 2012;38:966–970.
    1. Huang G, Gonzalez E, Peng PH, Lee R, Leeungurasatien T, He M, Porco T, Lin SC. Anterior chamber depth, iridocorneal angle width, and intraocular pressure changes after phacoemulsification: narrow versus open iridocorneal angles. Arch Ophthalmol. 2011;129:1283–1290.
    1. Tarongoy P, Ho CL, Walton DS. Angle-closure glaucoma: the role of the lens in the pathogenesis, prevention and treatment. Surv Ophthalmol. 2009;54:211–225.
    1. Crichton AC, Oryschak AF, McWhae JA, Kirker AW, Chacon-Andrade H. Postmortem microscopic evaluation and clinical correlation of a pseudophakic eye with and loss of zonular support. J Cataract Refract Surg. 2007;33:162–165.
    1. Doganay S, Tasar A, Cankaya C, Firat PG, Yologlu S. Evaluation of Pentacam-Scheimpflug imaging of anterior segment parameters in patients with pseudoexfoliation syndrome and pseudoexfoliative glaucoma. Clin Exp Optom. 2012;95:218–222.
    1. Seok JY, Lee D, Kyung H, Kim JM. Axial length change after implantable collamer lens implantation. J Korean Ophthalmol Soc. 2013;54:1675–1679.
    1. Bilak S, Simsek A, Capkin M, Guler M, Bilgin B. Biometric and intraocular pressure change after cataract surgery. Optom Vis Sci. 2015;92:464–470.
    1. Brown SVL. To evaluate change in axial length measurement after successful glaucoma filtering surgery. Ophthalmology. 1999;106:2311.

Source: PubMed

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