Fluoropolymer-coated dacron versus PTFE grafts for femorofemoral crossover bypass: randomised trial
J P Eiberg, O Røder, M Stahl-Madsen, N Eldrup, P Qvarfordt, A Laursen, M Greve, T Flörenes, O M Nielsen, C Seidelin, T Vestergaard-Andersen, T V Schroeder, J P Eiberg, O Røder, M Stahl-Madsen, N Eldrup, P Qvarfordt, A Laursen, M Greve, T Flörenes, O M Nielsen, C Seidelin, T Vestergaard-Andersen, T V Schroeder
Abstract
Objectives: To investigate whether patency of a thin walled 8 mm fluoropassivated Dacron graft was similar to that of a standard 8mm PTFE graft for femorofemoral crossover bypass surgery.
Design: A randomised multicentre clinical trial comparing two vascular grafts with participation of 10 departments of vascular surgery in Denmark, Sweden and Norway.
Patients and methods: 198 patients were randomised to PTFE (n=107) or fluoropolymer-coated Dacron grafts (n=91), 63% underwent surgery for claudication, 27% for ischaemic rest pain and 10% for tissue loss. The median follow-up time was 24 months (IQR 19-26 months).
Results: The primary patency rate of the two grafts was similar (log rank test: p=0.35). The primary patency rates (95% CI) for coated Dacron and PTFE grafts were 92% (86-98) and 94% (89-99) at 12 months and 87% (74-95) and 93% (87-99) at 24 months, respectively.
Conclusion: In patients with unilateral iliac artery disease not amenable to angioplasty, the femoral-femoral bypass is durable and effective. No difference in patency was found between the two graft materials (fluoropolymer coated Dacron and PTFE).
Source: PubMed