Ultrashort flare GnRH agonist combined with flexible multidose GnRH antagonist for patients with repeated IVF failures and poor embryo quality
Raoul Orvieto, Ravit Nahum, Jacob Rabinson, Ofer Gemer, Eyal Y Anteby, Simion Meltcer, Raoul Orvieto, Ravit Nahum, Jacob Rabinson, Ofer Gemer, Eyal Y Anteby, Simion Meltcer
Abstract
To evaluate the appropriate controlled ovarian hyperstimulation (COH) protocol in patients with repeated IVF failures and poor embryo quality we compared the stimulation characteristics of ten cycles which included ultrashort flare GnRH agonist combined with flexible multidose GnRH antagonist with the patients' earlier failed IVF attempts. The use of ultrashort GnRH agonist/GnRH antagonist COH protocol resulted in a significantly higher number and proportion of top-quality embryos, with a consequent improvement in clinical pregnancy rate (50%).
Source: PubMed