Scientist I - Upstream

Scientist I - Upstream Req ID #:  185434 Location: 

Rockville, MD, US, 20850 Rockville, MD, US, 20850 Rockville, MD, US, 20852 For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

IMPORTANT:   In order to be considered for this position, a resume/CV must be uploaded and submitted during the application process.  Please make sure work history and education are added correctly.  Job Summary  

The Scientist I, Upstream Process Development is responsible for studying properties of mammalian cell culture, developing new assays, and exploring new methods for viral vector production within the department of Process Development. 

Duties and Responsibilities 

•    Work with Process Development scientists and Director to design, plan, and conduct experiments to optimize and better characterize client/internal processes and projects. 

•    Lead execution of experiments from seed culture generation, data collection and final harvest of bioreactors. 

•    Sample of bioreactors, analysis, and data collection of current experiments for process development. 

•    Maintain an up-to-date inventory of all necessary laboratory and bioreactor consumables. 

•    Perform data analysis, prepare technical reports, write SOPs, and make internal and external presentations. 

•    Coordinate with Facilities and Engineering department and outside vendors for repair, maintenance, and/or calibration of laboratory equipment and systems. 

•    Preparation of reagents, media/buffer, and equipment as needed to support experiments. 

•    Responsible for documenting and organizing experiments according to Good Documentation Practices. 

•    Maintain good communication and collaboration with colleagues and junior members of team. 

•    Assistance with or support of manufacturing activities. 

•    Other responsibilities as needed.  Job Qualifications  

•    Bachelor of Science, Master’s Degree, or Ph.D. in Molecular Biology, Chemical Engineering, Biochemical Engineering, Microbiology, or related field 

•    0-2 years (Ph.D. level), 2-4 years (M.S. level) or 4-6 years (B.S. level) of relevant experience 

•    Experience with cell culture of various scales including shaking flasks, WAVE bags, and /or XDR bioreactor vessels

•    Must be a team player prepared to work in and embrace a team-based culture 

•    Proven troubleshooting, technical writing, problem solving and investigational skills 

•    Ability to think critically and creatively to identify and solve problems 

•    Proven ability to work independently and to work on multiple projects simultaneously 

•    Computer skills including Microsoft Office (Outlook and Excel) 

•    Well-organized and ability to pay attention to detail 

•    Excellent verbal and written communication skills 

IMPORTANT: A resume is required to be considered for this position. If you have not uploaded your resume in your candidate profile, please return to upload field and attach your resume/CV. 

Vaccine Mandate

Charles River is a U.S. Federal Contractor.  As a result, we must follow the Presidential Executive Order to mandate vaccinations, and ensure our employees are fully vaccinated against COVID-19.  Our main priority is the wellbeing, health, and safety of our people. We require proof of vaccination from all employees. 

Anyone with requests for disability-related and/or religious exemptions should contact Talent Acquisition (crrecruitment_US@crl.com) so that information can be provided about the accommodation process at Charles River.

About Biologics Testing Solutions

With more than 50 years of experience and proven regulatory expertise, the Charles River Biologics group can address challenging projects for biotechnology and pharmaceutical companies worldwide. Offering a variety of services such as contamination and impurity testing, protein characterization, bioassays, viral clearance studies and stability and lot release programs, we support clients throughout the biologic development cycle, from the establishment and characterization of cell banks through preclinical and clinical studies to marketed products. Whether clients need stand-alone services, a unique package of testing, or insourced support, our Biologics group can create a custom solution to suit their needs.  Each year more than 20,000 biologic testing reports are sent each and over 200 licenses products are supported by our biologics testing solutions team.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 18,000 employees within 100 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. 

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of >80% of the drugs approved by the FDA for the past 3 years.

Equal Employment Opportunity

Charles River Laboratories is an Equal Opportunity Employer - all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to crrecruitment_US@crl.com. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.

Nearest Major Market: Washington DC

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